Detalhe da pesquisa
1.
Identification and targeting of novel CDK9 complexes in acute myeloid leukemia.
Blood
; 133(11): 1171-1185, 2019 03 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-30587525
2.
Merestinib blocks Mnk kinase activity in acute myeloid leukemia progenitors and exhibits antileukemic effects in vitro and in vivo.
Blood
; 128(3): 410-4, 2016 07 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-27307295
3.
BH3 mimetics and multi-kinase inhibition in AML.
Blood
; 119(25): 5947-8, 2012 Jun 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-22730522
4.
Targeting CHAF1B Enhances IFN Activity against Myeloproliferative Neoplasm Cells.
Cancer Res Commun
; 3(5): 943-951, 2023 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37377894
5.
SLFN11 negatively regulates non-canonical NFkB signaling to promote glioblastoma progression.
Cancer Res Commun
; 2(9): 966-978, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-36382088
6.
Discovery of a signaling feedback circuit that defines interferon responses in myeloproliferative neoplasms.
Nat Commun
; 13(1): 1750, 2022 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35365653
7.
Inhibitory effects of Tomivosertib in acute myeloid leukemia.
Oncotarget
; 12(10): 955-966, 2021 May 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34012509
8.
OTS167 blocks FLT3 translation and synergizes with FLT3 inhibitors in FLT3 mutant acute myeloid leukemia.
Blood Cancer J
; 11(3): 48, 2021 03 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33658483
9.
Schlafen 5 as a novel therapeutic target in pancreatic ductal adenocarcinoma.
Oncogene
; 40(18): 3273-3286, 2021 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33846574
10.
Pharmacological mTOR targeting enhances the antineoplastic effects of selective PI3Kα inhibition in medulloblastoma.
Sci Rep
; 9(1): 12822, 2019 09 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-31492956
11.
Discovery of novel Mnk inhibitors using mutation-based induced-fit virtual high-throughput screening.
Chem Biol Drug Des
; 94(4): 1813-1823, 2019 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31260185
12.
Inhibitory effects of SEL201 in acute myeloid leukemia.
Oncotarget
; 10(67): 7112-7121, 2019 Dec 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-31903169
13.
Potent Antineoplastic Effects of Combined PI3Kα-MNK Inhibition in Medulloblastoma.
Mol Cancer Res
; 17(6): 1305-1315, 2019 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-30842251
14.
Differential Response of Glioma Stem Cells to Arsenic Trioxide Therapy Is Regulated by MNK1 and mRNA Translation.
Mol Cancer Res
; 16(1): 32-46, 2018 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29042487
15.
Pre-clinical evidence of PIM kinase inhibitor activity in BCR-ABL1 unmutated and mutated Philadelphia chromosome-positive (Ph+) leukemias.
Oncotarget
; 6(32): 33206-16, 2015 Oct 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-26375673
16.
Direct binding of arsenic trioxide to AMPK and generation of inhibitory effects on acute myeloid leukemia precursors.
Mol Cancer Ther
; 14(1): 202-12, 2015 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-25344585
17.
Dual targeting of acute myeloid leukemia progenitors by catalytic mTOR inhibition and blockade of the p110α subunit of PI3 kinase.
Oncotarget
; 6(10): 8062-70, 2015 Apr 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-25823922
18.
Human Schlafen 5 (SLFN5) Is a Regulator of Motility and Invasiveness of Renal Cell Carcinoma Cells.
Mol Cell Biol
; 35(15): 2684-98, 2015 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-26012550
19.
Central role of ULK1 in type I interferon signaling.
Cell Rep
; 11(4): 605-17, 2015 Apr 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-25892232
20.
Autophagy is a survival mechanism of acute myelogenous leukemia precursors during dual mTORC2/mTORC1 targeting.
Clin Cancer Res
; 20(9): 2400-9, 2014 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24610825