Pesquisa | BVS IEC

1.

A regulatory circuit controlled by extranuclear and nuclear retinoic acid receptor α determines T cell activation and function.

Larange, Alexandre; Takazawa, Ikuo; Kakugawa, Kiyokazu; Thiault, Nicolas; Ngoi, SooMun; Olive, Meagan E; Iwaya, Hitoshi; Seguin, Laetitia; Vicente-Suarez, Ildefonso; Becart, Stephane; Verstichel, Greet; Balancio, Ann; Altman, Amnon; Chang, John T; Taniuchi, Ichiro; Lillemeier, Bjorn; Kronenberg, Mitchell; Myers, Samuel A; Cheroutre, Hilde.

Immunity ; 56(9): 2054-2069.e10, 2023 09 12.

Artigo em Inglês | MEDLINE | ID: mdl-37597518

2.

Protein kinase C-Î· controls CTLA-4-mediated regulatory T cell function.

Kong, Kok-Fai; Fu, Guo; Zhang, Yaoyang; Yokosuka, Tadashi; Casas, Javier; Canonigo-Balancio, Ann J; Becart, Stephane; Kim, Gisen; Yates, John R; Kronenberg, Mitchell; Saito, Takashi; Gascoigne, Nicholas R J; Altman, Amnon.

Nat Immunol ; 15(5): 465-72, 2014 May.

Artigo em Inglês | MEDLINE | ID: mdl-24705298

3.

Accelerating Lead Identification by High Throughput Virtual Screening: Prospective Case Studies from the Pharmaceutical Industry.

Damm-Ganamet, Kelly L; Arora, Nidhi; Becart, Stephane; Edwards, James P; Lebsack, Alec D; McAllister, Heather M; Nelen, Marina I; Rao, Navin L; Westover, Lori; Wiener, John J M; Mirzadegan, Taraneh.

J Chem Inf Model ; 59(5): 2046-2062, 2019 05 28.

Artigo em Inglês | MEDLINE | ID: mdl-30817167

4.

SLAT promotes TCR-mediated, Rap1-dependent LFA-1 activation and adhesion through interaction of its PH domain with Rap1.

Côte, Marjorie; Fos, Camille; Canonigo-Balancio, Ann J; Ley, Klaus; Bécart, Stéphane; Altman, Amnon.

J Cell Sci ; 128(23): 4341-52, 2015 Dec 01.

Artigo em Inglês | MEDLINE | ID: mdl-26483383

5.

Tyrosine-phosphorylation-dependent translocation of the SLAT protein to the immunological synapse is required for NFAT transcription factor activation.

Bécart, Stéphane; Balancio, Ann J Canonigo; Charvet, Céline; Feau, Sonia; Sedwick, Caitlin E; Altman, Amnon.

Immunity ; 29(5): 704-19, 2008 Nov 14.

Artigo em Inglês | MEDLINE | ID: mdl-18976935

6.

SLAT regulates CD8+ T cell clonal expansion in a Cdc42- and NFAT1-dependent manner.

Feau, Sonia; Schoenberger, Stephen P; Altman, Amnon; Bécart, Stéphane.

J Immunol ; 190(1): 174-83, 2013 Jan 01.

Artigo em Inglês | MEDLINE | ID: mdl-23197258

7.

Does Def6 deficiency cause autoimmunity?

Altman, Amnon; Bécart, Stephane.

Immunity ; 31(1): 1-2; author reply 2-3, 2009 Jul 17.

Artigo em Inglês | MEDLINE | ID: mdl-19604483

8.

SWAP-70-like adapter of T cells: a novel Lck-regulated guanine nucleotide exchange factor coordinating actin cytoskeleton reorganization and Ca2+ signaling in T cells.

Bécart, Stéphane; Altman, Amnon.

Immunol Rev ; 232(1): 319-33, 2009 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-19909373

9.

Cytotoxic CD8⁺ T cells target citrullinated antigens in rheumatoid arthritis.

Moon, Jae-Seung; Younis, Shady; Ramadoss, Nitya S; Iyer, Radhika; Sheth, Khushboo; Sharpe, Orr; Rao, Navin L; Becart, Stephane; Carman, Julie A; James, Eddie A; Buckner, Jane H; Deane, Kevin D; Holers, V Michael; Goodman, Susan M; Donlin, Laura T; Davis, Mark M; Robinson, William H.

Nat Commun ; 14(1): 319, 2023 01 19.

Artigo em Inglês | MEDLINE | ID: mdl-36658110

10.

Randomized phase I trial of antigen-specific tolerizing immunotherapy with peptide/calcitriol liposomes in ACPA+ rheumatoid arthritis.

Sonigra, Amee; Nel, Hendrik J; Wehr, Pascale; Ramnoruth, Nishta; Patel, Swati; van Schie, Karin A; Bladen, Maxwell W; Mehdi, Ahmed M; Tesiram, Joanne; Talekar, Meghna; Rossjohn, Jamie; Reid, Hugh H; Stuurman, Frederik E; Roberts, Helen; Vecchio, Phillip; Gourley, Ian; Rigby, Mark; Becart, Stephane; Toes, Rene Em; Scherer, Hans Ulrich; Lê Cao, Kim-Anh; Campbell, Kim; Thomas, Ranjeny.

JCI Insight ; 7(20)2022 10 24.

Artigo em Inglês | MEDLINE | ID: mdl-36278483

11.

SLAT/Def6 plays a critical role in the development of Th17 cell-mediated experimental autoimmune encephalomyelitis.

Canonigo-Balancio, Ann J; Fos, Camille; Prod'homme, Thomas; Bécart, Stéphane; Altman, Amnon.

J Immunol ; 183(11): 7259-67, 2009 Dec 01.

Artigo em Inglês | MEDLINE | ID: mdl-19915062

12.

The role of posttranslational modifications in generating neo-epitopes that bind to rheumatoid arthritis-associated HLA-DR alleles and promote autoimmune T cell responses.

Becart, Stephane; Whittington, Karen B; Prislovsky, Amanda; Rao, Navin L; Rosloniec, Edward F.

PLoS One ; 16(1): e0245541, 2021.

Artigo em Inglês | MEDLINE | ID: mdl-33465118

13.

SLAT regulates Th1 and Th2 inflammatory responses by controlling Ca2+/NFAT signaling.

Bécart, Stéphane; Charvet, Céline; Canonigo Balancio, Ann J; De Trez, Carl; Tanaka, Yoshihiko; Duan, Wei; Ware, Carl; Croft, Michael; Altman, Amnon.

J Clin Invest ; 117(8): 2164-75, 2007 Aug.

Artigo em Inglês | MEDLINE | ID: mdl-17657315

14.

Citrullination only infrequently impacts peptide binding to HLA class II MHC.

Sidney, John; Becart, Stephane; Zhou, Mimi; Duffy, Karen; Lindvall, Mikaela; Moore, Erin C; Moore, Eugene L; Rao, Tadimeti; Rao, Navin; Nielsen, Morten; Peters, Bjoern; Sette, Alessandro.

PLoS One ; 12(5): e0177140, 2017.

Artigo em Inglês | MEDLINE | ID: mdl-28481943

15.

Cognate MHC-TCR interaction leads to apoptosis of antigen-presenting cells.

Setterblad, Niclas; Blancheteau, Vincent; Delaguillaumie, Alix; Michel, Frédérique; Bécart, Stéphane; Lombardi, Giovanna; Acuto, Oreste; Charron, Dominique; Mooney, Nuala.

J Leukoc Biol ; 75(6): 1036-44, 2004 Jun.

Artigo em Inglês | MEDLINE | ID: mdl-14982950

16.

Forefront news in immunology from France: annual meeting of the French Society of Immunologists.

Bécart, Stéphane; Boniface, Katia; Cherrier, Marie; Lanvin, Olivia; Soulard, Valérie; Toulza, Frédéric.

Eur Cytokine Netw ; 14(2): 115-9, 2003.

Artigo em Inglês | MEDLINE | ID: mdl-12957793

17.

Association of the EF-hand and PH domains of the guanine nucleotide exchange factor SLAT with IP3 receptor 1 promotes Ca²âº signaling in T cells.

Fos, Camille; Becart, Stephane; Canonigo Balancio, Ann J; Boehning, Darren; Altman, Amnon.

Sci Signal ; 7(345): ra93, 2014 Sep 30.

Artigo em Inglês | MEDLINE | ID: mdl-25270259

18.

Adaptor protein SLAT modulates Fcgamma receptor-mediated phagocytosis in murine macrophages.

Mehta, Harshini; Glogauer, Michael; Bécart, Stephane; Altman, Amnon; Coggeshall, K Mark.

J Biol Chem ; 284(18): 11882-91, 2009 May 01.

Artigo em Inglês | MEDLINE | ID: mdl-19251698

19.

Cell-mediated immunity and vaccines.

Kumari, Jaya; Selvan, Senthamil R; Becart, Stephane; Chattopadhyay, Subhasis; Dalmo, Roy Ambli.

J Immunol Res ; 2014: 632632, 2014.

Artigo em Inglês | MEDLINE | ID: mdl-24741611

20.

Vav1 promotes T cell cycle progression by linking TCR/CD28 costimulation to FOXO1 and p27kip1 expression.

Charvet, Céline; Canonigo, Ann Janette; Bécart, Stéphane; Maurer, Ulrich; Miletic, Ana V; Swat, Wojciech; Deckert, Marcel; Altman, Amnon.

J Immunol ; 177(8): 5024-31, 2006 Oct 15.

Artigo em Inglês | MEDLINE | ID: mdl-17015685

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Instituto Evandro Chagas

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