Detalhe da pesquisa
1.
HDAC6 inhibition restores TDP-43 pathology and axonal transport defects in human motor neurons with TARDBP mutations.
EMBO J
; 40(7): e106177, 2021 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33694180
2.
HNRNPK alleviates RNA toxicity by counteracting DNA damage in C9orf72 ALS.
Acta Neuropathol
; 144(3): 465-488, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35895140
3.
Recent Insights on Alzheimer's Disease Originating from Yeast Models.
Int J Mol Sci
; 19(7)2018 07 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29970827
4.
Toxic gain-of-function mechanisms in C9orf72 ALS-FTD neurons drive autophagy and lysosome dysfunction.
Autophagy
; : 1-3, 2024 Apr 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-38615685
5.
A toxic gain-of-function mechanism in C9orf72 ALS impairs the autophagy-lysosome pathway in neurons.
Acta Neuropathol Commun
; 11(1): 151, 2023 09 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-37723585
6.
The role of inflammation in neurodegeneration: novel insights into the role of the immune system in C9orf72 HRE-mediated ALS/FTD.
Mol Neurodegener
; 17(1): 22, 2022 03 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-35303907
7.
C9orf72 ALS-FTD: recent evidence for dysregulation of the autophagy-lysosome pathway at multiple levels.
Autophagy
; 17(11): 3306-3322, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-33632058
8.
Human motor units in microfluidic devices are impaired by FUS mutations and improved by HDAC6 inhibition.
Stem Cell Reports
; 16(9): 2213-2227, 2021 09 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-33891869
9.
Generation of Human Motor Units with Functional Neuromuscular Junctions in Microfluidic Devices.
J Vis Exp
; (175)2021 09 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34570099
10.
C9orf72-derived arginine-containing dipeptide repeats associate with axonal transport machinery and impede microtubule-based motility.
Sci Adv
; 7(15)2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33837088