RESUMO
Radiation therapy is one of the cornerstones for the treatment of thoracic malignancies. Although advances in radiation therapy technology have improved the delivery of radiation considerably, adverse effects are still common. Postirradiation changes affect the organ or tissue treated and the neighboring structures. Advances in external-beam radiation delivery techniques and how these techniques affect the expected thoracic radiation-induced changes are described. In addition, how to distinguish these expected changes from complications such as infection and radiation-induced malignancy, and identify treatment failure, that is, local tumor recurrence, is reviewed. ©RSNA, 2019.
Assuntos
Mama/efeitos da radiação , Coração/efeitos da radiação , Pulmão/efeitos dos fármacos , Neoplasias Induzidas por Radiação/diagnóstico por imagem , Lesões por Radiação/diagnóstico por imagem , Radiografia/métodos , Radioterapia/efeitos adversos , Osso e Ossos/diagnóstico por imagem , Osso e Ossos/efeitos da radiação , Mama/diagnóstico por imagem , Feminino , Coração/diagnóstico por imagem , Humanos , Pulmão/diagnóstico por imagem , Linfonodos/diagnóstico por imagem , Linfonodos/efeitos da radiação , Masculino , Doses de Radiação , Lesões por Radiação/etiologia , Radioterapia/métodos , Tomografia Computadorizada por Raios XRESUMO
Radiotherapy is one of the cornerstones for the treatment of thoracic malignancies. The goal of radiotherapy is to deliver maximal dose to the tumor while minimizing damage to surrounding normal anatomical structures. Although advances in radiotherapy technology have considerably improved radiation delivery, potential adverse effects are still common. Post radiation changes to the chest may include different structures such as the lung, heart, great vessels, and esophagus. The purpose of this manuscript is to illustrate the post radiotherapy changes to these anatomical structures resulting from external beam radiotherapy, as well as discuss imaging pitfalls to prevent radiologist's interpretation errors.
Assuntos
Neoplasias , Tórax , Humanos , Pulmão/diagnóstico por imagem , Tórax/diagnóstico por imagem , Tomografia Computadorizada por Raios XRESUMO
Radiation therapy is an important modality in the treatment of patients with lung cancer. Recent advances in delivering radiotherapy were designed to improve loco-regional tumor control by focusing higher doses on the tumor. More sophisticated techniques in treatment planning include 3-dimensional conformal radiation therapy, intensity-modulated radiotherapy, stereotactic body radiotherapy, and proton therapy. These methods may result in nontraditional patterns of radiation injury and various radiologic appearances that can be mistaken for recurrence, infection and other lung diseases. Knowledge of radiological manifestations, awareness of new radiation delivery techniques and correlation with radiation treatment plans are essential in order to correctly interpret imaging in these patients.
Assuntos
Neoplasias Pulmonares/diagnóstico por imagem , Neoplasias Pulmonares/radioterapia , Humanos , Pulmão/diagnóstico por imagemRESUMO
Malignant pleural mesothelioma is the most common primary neoplasm of the pleura. Imaging evaluation is essential in diagnosis, staging, and assessment of treatment response in malignant pleural mesothelioma. Computed tomography is the most commonly used modality for tumor staging. Assessment of tumor extension and lymph node involvement is essential in imaging evaluation as locally advanced tumors are amenable to resection. Knowledge of the full imaging spectrum of this rare disease, differential diagnosis, staging classification, and the current guidelines for diagnostic evaluation and follow-up are essential in accurate interpretation to optimize patient management.