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Am J Cardiol ; 111(3): 445-7, 2013 Feb 01.
Artigo em Inglês | MEDLINE | ID: mdl-23186600

RESUMO

The investigators describe the clinical course of a 26-year-old-man who was brought to the emergency department in a comatose state with status epilepticus after smoking a large amount of crack cocaine. In the emergency department, he was intubated because of depressed mental status and respiratory acidosis. His troponin I remained negative, and electrocardiography showed wide-complex tachycardia with a prolonged corrected QT interval. Because of the corrected QT interval prolongation and wide-complex tachycardia, the patient was started on intravenous magnesium sulfate and sodium bicarbonate. Despite these interventions, no improvement in cardiac rhythm was observed, and electrocardiography continued to show wide-complex tachycardia. The patient became more unstable from a cardiovascular standpoint, with a decrease in blood pressure to 85/60 mm Hg. He was then given 100 ml of 20% lipid emulsion (Intralipid). Within 10 minutes of starting the infusion of 20% lipid emulsion, wide-complex tachycardia disappeared, with an improvement in systemic blood pressure to 120/70 mm Hg. Repeat electrocardiography after the infusion of intravenous lipid emulsion showed regular sinus rhythm with normal QRS and corrected QT intervals. The patient was successfully extubated on day 8 of hospitalization and discharged home on day 10. His cardiac rhythm and blood pressure remained stable throughout his further stay in the hospital.


Assuntos
Transtornos Relacionados ao Uso de Cocaína/complicações , Cocaína Crack/intoxicação , Overdose de Drogas/tratamento farmacológico , Eletrocardiografia/efeitos dos fármacos , Emulsões Gordurosas Intravenosas/uso terapêutico , Coração/efeitos dos fármacos , Taquicardia/tratamento farmacológico , Adulto , Overdose de Drogas/complicações , Seguimentos , Coração/fisiopatologia , Humanos , Masculino , Taquicardia/induzido quimicamente
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