Black individuals' suspicion of Whites' motives negatively predicts expected efficacy with White social partners.

OBJECTIVES: Interracial efficacy is critical to intergroup interactions. However, the antecedents of interracial efficacy are unclear and rarely studied from the perspectives of Black individuals. The current work addresses these empirical gaps by testing whether individual differences in suspicion of Whites' motives negatively relate to expected efficacy in interracial interactions. Suspicion was operationalized as beliefs that Whites' positivity toward people of color (POC) is primarily motivated by concerns with appearing prejudiced. METHOD: Four studies employing correlational and experimental vignette designs with Black adult participants (Ntotal = 2,295; ∼60% female) tested suspicion's hypothesized negative relation with three conceptions of interracial efficacy (general efficacy, liking-based efficacy, and respect-based efficacy). RESULTS: Four studies provided consistent evidence that suspicion of Whites' motives negatively related to expected efficacy in interactions with White social partners. Moreover, this relationship was unique to contexts with White partners and did not extend to imagined interactions with Black partners or members of other outgroup members (e.g., Latine partners). CONCLUSIONS: Results further suggest suspicion increases expected threat (i.e., anticipated uncertainty/anxiety), which undermines Black individuals' confidence in interactions with White partners. (PsycInfo Database Record (c) 2023 APA, all rights reserved).

Facing social exclusion: a facial EMG examination of the reaffiliative function of smiling.

Social exclusion influences how expressions are perceived and the tendency of the perceiver to mimic them. However, less is known about social exclusion's effect on one's own facial expressions. The aim of the present study was to identify the effects of social exclusion on Duchenne smiling behaviour, defined as activity of both zygomaticus major and the orbicularis oculi muscles. Utilising a within-subject's design, participants took part in the Cyberball Task in which they were both included and excluded while facial electromyography was measured. We found that during the active experience of social exclusion, participants showed greater orbicularis oculi activation when compared to the social inclusion condition. Further, we found that across both conditions, participants showed greater zygomaticus major muscle activation the longer they engaged in the Cyberball Task. Order of condition also mattered, with those who experienced social exclusion before social inclusion showing the greatest overall muscle activation. These results are consistent with an affiliative function of smiling, particularly as social exclusion engaged activation of muscles associated with a Duchenne smile.

Motives matter: White instructors' external race-based motives undermine trust and belonging for Black college students.

OBJECTIVE: Trust is fundamental to successful educational relationships. Yet, numerous barriers inhibit the development of trust between students of color (SOC) and White instructors. The current research examined a metacognitive obstacle to the development of cross-race classroom trust: Primarily External Race Motives (PERM). PERM was defined as the experience that instructors were more concerned with avoiding the appearance of prejudice than having self-directed egalitarian motives. METHOD: Using within-subjects vignettes (n = 313; 74.8% female), between-subjects cross-sectional designs (n = 386; 70.5% female), and longitudinal methods (n = 135; 45.2% female), the current work tested the primary hypothesis that PERM would undermine instructor trust and classroom belonging. Hypotheses were tested with Black adults (Study 1) and college students (Studies 2 and 3). RESULTS AND CONCLUSIONS: Whether with hypothetical, past, or present White educators, feeling that instructors have primarily external race-based motives undermined instructor trust and classroom belonging. In all studies, the relationship between PERM and classroom belonging was mediated by instructor (mis)trust. The results provide evidence that motives viewed to be primarily external undermine instructional relationships for SOC. (PsycInfo Database Record (c) 2022 APA, all rights reserved).

The Societal Readiness Thinking Tool: A Practical Resource for Maturing the Societal Readiness of Research Projects.

In this paper, we introduce the Societal Readiness (SR) Thinking Tool to aid researchers and innovators in developing research projects with greater responsiveness to societal values, needs, and expectations. The need for societally-focused approaches to research and innovation-complementary to Technology Readiness (TR) frameworks-is presented. Insights from responsible research and innovation (RRI) concepts and practice, organized across critical stages of project-life cycles are discussed with reference to the development of the SR Thinking Tool. The tool is designed to complement not only shortfalls in TR approaches, but also improve upon other efforts to integrate RRI, sustainability, and design thinking in research and innovation cycles. Operationalization and early-stage user tests of the Tool are reported, along with discussion of potential future iterations and applications.

Chronic dietary creatine enhances hippocampal-dependent spatial memory, bioenergetics, and levels of plasticity-related proteins associated with NF-κB.

The brain has a high demand for energy, of which creatine (Cr) is an important regulator. Studies document neurocognitive benefits of oral Cr in mammals, yet little is known regarding their physiological basis. This study investigated the effects of Cr supplementation (3%, w/w) on hippocampal function in male C57BL/6 mice, including spatial learning and memory in the Morris water maze and oxygen consumption rates from isolated mitochondria in real time. Levels of transcription factors and related proteins (CREB, Egr1, and IκB to indicate NF-κB activity), proteins implicated in cognition (CaMKII, PSD-95, and Egr2), and mitochondrial proteins (electron transport chain Complex I, mitochondrial fission protein Drp1) were probed with Western blotting. Dietary Cr decreased escape latency/time to locate the platform (P < 0.05) and increased the time spent in the target quadrant (P < 0.01) in the Morris water maze. This was accompanied by increased coupled respiration (P < 0.05) in isolated hippocampal mitochondria. Protein levels of CaMKII, PSD-95, and Complex 1 were increased in Cr-fed mice, whereas IκB was decreased. These data demonstrate that dietary supplementation with Cr can improve learning, memory, and mitochondrial function and have important implications for the treatment of diseases affecting memory and energy homeostasis.

Science Outside the Lab: Helping Graduate Students in Science and Engineering Understand the Complexities of Science Policy.

Helping scientists and engineers challenge received assumptions about how science, engineering, and society relate is a critical cornerstone for macroethics education. Scientific and engineering research are frequently framed as first steps of a value-free linear model that inexorably leads to societal benefit. Social studies of science and assessments of scientific and engineering research speak to the need for a more critical approach to the noble intentions underlying these assumptions. "Science Outside the Lab" is a program designed to help early-career scientists and engineers understand the complexities of science and engineering policy. Assessment of the program entailed a pre-, post-, and 1 year follow up survey to gauge student perspectives on relationships between science and society, as well as a pre-post concept map exercise to elicit student conceptualizations of science policy. Students leave Science Outside the Lab with greater humility about the role of scientific expertise in science and engineering policy; greater skepticism toward linear notions of scientific advances benefiting society; a deeper, more nuanced understanding of the actors involved in shaping science policy; and a continued appreciation of the contributions of science and engineering to society. The study presents an efficacious program that helps scientists and engineers make inroads into macroethical debates, reframe the ways in which they think about values of science and engineering in society, and more thoughtfully engage with critical mediators of science and society relationships: policy makers and policy processes.

Nonlinear relationships between eye gaze and recognition accuracy for ethnic ingroup and outgroup faces.

Researchers have used eye-tracking measures to explore the relationship between face encoding and recognition, including the impact of ethnicity on this relationship. Previous studies offer a variety of conflicting conclusions. This confusion may stem from misestimation of the relationship between encoding and recognition. First, most previous models fail to account for the structure of eye-tracking data, potentially falling prey to Simpson's paradox. Second, previous models assume a linear relationship between attention (e.g., the number of fixations to a to-be-remembered face) and recognition accuracy. Two eye-tracking studies (Ns = 41, 59), one online experiment that manipulates exposure (N = 150), and a mega-analysis examine the effects of ethnicity using what we believe to be more appropriate analytical models. Across studies and measures, we document a novel, critical pattern: The relationship between attention and recognition is nonlinear and negatively accelerating. At low levels of baseline attention, a small increment in attention improves recognition. However, as attention increases further, increments yield smaller and smaller benefits. This finding parallels work in learning and memory. In models that allow for nonlinearity, we find evidence that central features (eyes, nose, and mouth) generally contribute to recognition accuracy, potentially resolving disagreements in the field. We also find that the effects of attention on recognition are similar for ingroup and outgroup faces, which have important implications for theories of perceptual expertise. (PsycInfo Database Record (c) 2024 APA, all rights reserved).

Governing beyond the project: Refocusing innovation governance in emerging science and technology funding.

This article analyses how a recent idiom of innovation governance, 'responsible innovation', is enacted in practice, how this shapes innovation processes, and what aspects of innovation are left untouched. Within this idiom, funders typically focus on one point in an innovation system: researchers in projects. However, the more transformational aspirations of responsible innovation are circumscribed by this context. Adopting a mode of critique that assembles, this article considers some alternative approaches to governing the shared trajectories of science, technology, and society. Using the idea of institutional invention to focus innovation governance on four inflection points-agendas, calls, spaces, evaluation-would allow funding organizations and researchers to look 'beyond the project', developing new methods to unpack and reflect on assumed purposes of science, technology, and innovation, and to potentially reconfigure the institutions that condition scientific practice.

The European Commission's Green Deal is an opportunity to rethink harmful practices of research and innovation policy.

The European Union's Green Deal and associated policies, aspiring to long-term environmental sustainability, now require economic activities to 'do no significant harm' to EU environmental objectives. The way the European Commission is enacting the do no significant harm principle relies on quantitative tools that try to identify harm and adjudicate its significance. A reliance on established technical approaches to assessing such questions ignores the high levels of imprecision, ambiguity, and uncertainty-levels often in flux-characterizing the social contexts in which harms emerge. Indeed, harm, and its significance, are relational, not absolute. A better approach would thus be to acknowledge the relational nature of harm and develop broad capabilities to engage and 'stay with' the harm. We use the case of European research and innovation activities to expose the relational nature of harm, and explore an alternative and potentially more productive approach that departs from attempts to unilaterally or uniformly claim to know or adjudicate what is or is not significantly harmful. In closing, we outline three ways research and innovation policy-makers might experiment with reconfiguring scientific and technological systems and practices to better address the significant harms borne by people, other-than-human beings, and ecosystems.

Race-based biases in psychological distress and treatment judgments.

Racism creates and sustains mental health disparities between Black and White Americans and the COVID-19 pandemic and ongoing harassment directed at Black Americans has exacerbated these inequities. Yet, as the mental health needs of Black Americans rise, there is reason to believe the public paradoxically believes that psychopathology hurts Black individuals less than White individuals and these biased distress judgments affect beliefs about treatment needs. Four studies (two pre-registered) with participants from the American public and the field of mental health support this hypothesis. When presented with identical mental illnesses (e.g., depression, anxiety, schizophrenia), both laypeople and clinicians believed that psychopathology would be less distressing to Black relative to White individuals. These distress biases mediate downstream treatment judgments. Across numerous contexts, racially-biased judgments of psychological distress may negatively affect mental healthcare and social support for Black Americans.

NF-κB p50 subunit knockout impairs late LTP and alters long term memory in the mouse hippocampus.

BACKGROUND: Nuclear factor kappa B (NF-κB) is a transcription factor typically expressed with two specific subunits (p50, p65). Investigators have reported that NF-κB is activated during the induction of in vitro long term potentiation (LTP), a paradigm of synaptic plasticity and correlate of memory, suggesting that NF-κB may be necessary for some aspects of memory encoding. Furthermore, NF-κB has been implicated as a potential requirement in behavioral tests of memory. Unfortunately, very little work has been done to explore the effects of deleting specific NF-κB subunits on memory. Studies have shown that NF-κB p50 subunit deletion (p50-/-) leads to memory deficits, however some recent studies suggest the contrary where p50-/- mice show enhanced memory in the Morris water maze (MWM). To more critically explore the role of the NF-κB p50 subunit in synaptic plasticity and memory, we assessed long term spatial memory in vivo using the MWM, and synaptic plasticity in vitro utilizing high frequency stimuli capable of eliciting LTP in slices from the hippocampus of NF-κB p50-/- versus their controls (p50+/+). RESULTS: We found that the lack of the NF-κB p50 subunit led to significant decreases in late LTP and in selective but significant alterations in MWM tests (i.e., some improvements during acquisition, but deficits during retention). CONCLUSIONS: These results support the hypothesis that the NF-κ p50 subunit is required in long term spatial memory in the hippocampus.

Perception and motivation in face recognition: a critical review of theories of the Cross-Race Effect.

Although humans possess well-developed face processing expertise, face processing is nevertheless subject to a variety of biases. Perhaps the best known of these biases is the Cross-Race Effect--the tendency to have more accurate recognition for same-race than cross-race faces. The current work reviews the evidence for and provides a critical review of theories of the Cross-Race Effect, including perceptual expertise and social cognitive accounts of the bias. The authors conclude that recent hybrid models of the Cross-Race Effect, which combine elements of both perceptual expertise and social cognitive frameworks, provide an opportunity for theoretical synthesis and advancement not afforded by independent expertise or social cognitive models. Finally, the authors suggest future research directions intended to further develop a comprehensive and integrative understanding of biases in face recognition.

Narcissistic grandiosity and risky health behaviors in college students.

Objective This study explored associations between narcissistic grandiosity (including its component traits) and reported risky health behaviors in college students. Participants: College men and women (N = 122) participated between December 2015 and January 2016. Methods: Participants completed self-report measures of grandiosity, alcohol consumption, number of sex partners, and condom use. Results: Grandiosity was positively associated with alcohol consumption. Gender interacted with grandiose traits, driving associations with reported sexual behaviors. College men high in entitlement/exploitativeness reported more sex partners. Grandiose exhibitionism was associated with condom use among women but not men, such that college women higher in grandiose exhibitionism were more likely to report not using a condom with their most recent partner. Conclusions: Grandiosity (and grandiose traits) may influence health behavior and/or the reporting of health behavior in college students, but associations may differ for men and women.

Stress-responses to ostracism: Examining cortisol and affective reactivity to in-person and online exclusion.

Ostracism is associated with poor outcomes, but it is unclear if online versus in-person ostracism elicits divergent psychological and physiological responses. Participants (N = 54) were randomly assigned to online or in-person ostracism, and provided pre- and post-ostracism measures of affect, self-esteem, self-feelings, and salivary cortisol. No significant changes in negative affect, self-esteem, or self-feelings emerged, nor were there differences by ostracism condition. Both ostracism conditions decreased positive affect (stronger online) and lowered cortisol. Extending prior work, ostracism appears to reliably decrease positive affect (especially online) but may not be threatening to the self; moreover, ostracism may reliably elicit acute cortisol declines.

Social exclusion enhances affiliative signaling.

Reciprocating smiles is important for maintaining social bonds as it both signals affiliative intent and elicits affiliative responses. Feelings of social exclusion may increase mimicry as a means to regulate affiliative bonds with others. In this study, we examined whether feelings of exclusion lead people to selectively reciprocate the facial expressions of more affiliative-looking people. Participants first wrote about either a time they were excluded or a neutral event. They then classified 20 smiles-half spontaneous smiles and half posed. Facial electromyography recorded smile muscle activity. Excluded participants distinguished the two smile types better than controls. Excluded participants also showed greater zygomaticus major (mouth smiling) activity toward enjoyment smiles compared to posed smiles; control participants did not. Orbicularis oculi (eye crinkle) activity matched that of the smile type viewed, but did not vary by exclusion condition. Affiliative social regulation is discussed as a possible explanation for these effects.

Reconnecting to Internal Sensation and Experiences: A Pilot Feasibility Study of an Online Intervention to Improve Interoception and Reduce Suicidal Ideation.

Risk factors that are strongly associated with suicide and are amenable to intervention are in need of discovery. This three-study investigation demonstrates that an intervention designed to improve interoception-one potential suicide risk factor-may reduce suicide-related outcomes. Study 1 included 136 undergraduate participants and found that relative to a control condition, participating in a progressive muscle relaxation exercise was associated with reduced implicit identification with suicide through greater body trust, which is one domain of interoception that is consistently linked to suicide-related outcomes. Study 2 included 97 MTurk participants and found that relative to a control condition, participating in a body functionality writing exercise was associated with greater awareness of the body as a whole. Study 3 was a pilot study of a four-session online intervention designed to increase interoception. Study 3 included a sample of 22 clinical participants who completed pre- and postintervention assessments. Participants rated the intervention as highly acceptable and moderately effective. Moreover, the intervention was associated with improvements in interoception and reductions in suicidal ideation, general psychological symptoms, and disordered-eating symptoms. Overall, these findings indicate that our online interoceptive awareness training is acceptable and may be associated with improvements in clinical outcomes. Randomized controlled trials are needed to explore whether the intervention's purported mechanism-improved interoception-leads to changes in clinical outcomes.

Good Cop, Bad Cop: Race-Based Differences in Mental Representations of Police.

The current work investigates race-based biases in conceptualization of the facial appearance of police. We employ a reverse correlation procedure to demonstrate that Black Americans, relative to White Americans, conceptualize police officers' faces as more negative, less positive, and more dominant. We further find that these differential representations have implications for interactions with police. When naïve participants (of various races) viewed images of police officers generated by Black Americans (relative to those generated by White Americans), they responded with greater anticipated anxiety and reported more fight-or-flight behavioral intentions. Across four studies, findings suggest Black and White Americans conceptualize police and police-citizen interactions fundamentally differently. These findings have important theoretical (e.g., using reverse correlation to document the mental representations held by minority group members) and practical implications (e.g., identifying race-based differences in representations of police that may affect community-police relations).

Sex-Specific Effects of Chronic Creatine Supplementation on Hippocampal-Mediated Spatial Cognition in the 3xTg Mouse Model of Alzheimer's Disease.

The creatine (Cr) energy system has been implicated in Alzheimer's disease (AD), including reductions in brain phosphoCr and Cr kinase, yet no studies have examined the neurobehavioral effects of Cr supplementation in AD, including the 3xTg mouse model. This studied investigated the effects of Cr supplementation on spatial cognition, plasticity- and disease-related protein levels, and mitochondrial function in the 3xTg hippocampus. Here, 3xTg mice were fed a control or Cr-supplemented (3% Cr (w/w)) diet for 8-9 weeks and tested in the Morris water maze. Mitochondrial oxygen consumption (Seahorse) and protein levels (Western blots) were measured in the hippocampus in subsets of mice. Overall, 3xTg females exhibited impaired memory as compared to males. In females, Cr supplementation decreased escape latency and was associated with increased spatial search strategy use. In males, Cr supplementation decreased the use of spatial search strategies. Pilot data indicated mitochondrial enhancements with Cr supplementation in both sexes. In females, Cr supplementation increased CREB phosphorylation and levels of IκB (NF-κB suppressor), CaMKII, PSD-95, and high-molecular-weight amyloid ß (Aß) species, whereas Aß trimers were reduced. These data suggest a beneficial preventative effect of Cr supplementation in females and warrant caution against Cr supplementation in males in the AD-like brain.

The affiliative consequences of same-race and cross-race mimicry.

Few studies have replicated and extended the classic mimicry → liking effect. The present research sought to (a) replicate the affiliative consequences of mimicry; (b) test whether the affiliative consequences hold in a context where mimicry may not be normative (i.e., cross-race interactions); and (c) investigate how excluded individuals respond to same- versus cross-race mimicry and non-mimicry. Participants wrote about a control topic or social exclusion and then engaged in a brief laboratory interaction in which they were mimicked or not mimicked by a confederate who was either same-race or cross-race. Then they reported how much they liked the confederate. Within the control condition, the effect of mimicry on affiliation depended on the race of the confederate - but this pattern did not emerge for excluded individuals. The study was unable to conclusively replicate and extend previous findings. The authors make recommendations to promote a more cumulative science of behavioral mimicry.

Validating the state motivation to foster social connections scale.

Motivations to foster social connections drive much of human behavior. While these motivations vary across both situations and time, no scale exists assessing them at the state level. In the current work, we develop such a state measure, yielding a two-factor solution: motivation to foster social connections with existing and with new social targets. Across nine studies with almost 2000 participants, the scale shows good factor structure and reliability, as well as convergent and divergent validity. In two experimental studies, it also showed sensitivity to manipulations of regulatory focus and hunger. Implications for future research on social interactions and other uses of the scale are discussed.