Detalhe da pesquisa
1.
Monocytes and Macrophages, Targets of Severe Acute Respiratory Syndrome Coronavirus 2: The Clue for Coronavirus Disease 2019 Immunoparalysis.
J Infect Dis
; 224(3): 395-406, 2021 08 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33493287
2.
Ezurpimtrostat, A Palmitoyl-Protein Thioesterase-1 Inhibitor, Combined with PD-1 Inhibition Provides CD8+ Lymphocyte Repopulation in Hepatocellular Carcinoma.
Target Oncol
; 19(1): 95-106, 2024 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-38133710
3.
Update on Autophagy Inhibitors in Cancer: Opening up to a Therapeutic Combination with Immune Checkpoint Inhibitors.
Cells
; 12(13)2023 06 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-37443736
4.
Cell and Animal Models for SARS-CoV-2 Research.
Viruses
; 14(7)2022 07 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35891487
5.
GNS561 Exhibits Potent Antiviral Activity against SARS-CoV-2 through Autophagy Inhibition.
Viruses
; 14(1)2022 01 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-35062337
6.
First-In-Human Effects of PPT1 Inhibition Using the Oral Treatment with GNS561/Ezurpimtrostat in Patients with Primary and Secondary Liver Cancers.
Liver Cancer
; 11(3): 268-277, 2022 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-35949290
7.
GNS561, a clinical-stage PPT1 inhibitor, is efficient against hepatocellular carcinoma via modulation of lysosomal functions.
Autophagy
; 18(3): 678-694, 2022 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-34740311
8.
GNS561, a New Autophagy Inhibitor Active against Cancer Stem Cells in Hepatocellular Carcinoma and Hepatic Metastasis from Colorectal Cancer.
J Cancer
; 12(18): 5432-5438, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34405006
9.
Influence of Plant Fraction, Soil, and Plant Species on Microbiota: a Multikingdom Comparison.
mBio
; 11(1)2020 02 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32019791
10.
GNS561 exhibits potent in vitro antiviral activity against SARS-CoV-2 through autophagy inhibition.
bioRxiv
; 2020 Oct 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-33052342
11.
Agricultural Selection of Wheat Has Been Shaped by Plant-Microbe Interactions.
Front Microbiol
; 11: 132, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32117153
12.
GNS561 acts as a potent anti-fibrotic and pro-fibrolytic agent in liver fibrosis through TGF-ß1 inhibition.
Ther Adv Chronic Dis
; 11: 2040622320942042, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32728410