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1.
Eur Rev Med Pharmacol Sci ; 18(8): 1176-80, 2014.
Artigo em Inglês | MEDLINE | ID: mdl-24817292

RESUMO

BACKGROUND: There are two equivalent in efficacy methods of the treatment of carotid artery stenosis: endarterectomy (CEA) and stenting (CAS), in which the blood flow increases in most patients by 20-40% over baseline, in some exceeding 100% and being symptomatic and leading to cerebral hyperperfusion syndrome (CHS). AIM: The aim of this study is to analyze the structure of neurological symptoms associated with CHS in patients with carotid artery revascularization. PATIENTS AND METHODS: Retrospective analysis included 1386 consecutive patients treated in the Department of General and Vascular Surgery between 2005 and 2011, with 625 of them were subjected to CEA and 761 to CAS. If neurological symptoms occurred, patients were consulted by a neurologist and ultrasonography (USG) examination and CT were performed. Neurological symptoms in patients with new onset of headache ipsilateral to the carotid revascularization were extracted from medical records and nursing documentation. RESULTS: Neurological symptoms attributed to CHS were observed in 66 (10.6%) of CEA and 61 (8.0 %) of CAS group. The frequency was similar in both groups (p = 0.43). The occurrence of epileptic attacks was similar in both study groups. The only difference was the less frequent falling of the lip in CAS group. Transient bradycardia and/or hypotension were observed in CAS (8.8% vs. 10.4% and 1.3% vs. 1.3%, respectively). No difference in stroke appearance between groups were found. CONCLUSIONS: The occurrence of neurological symptoms attributable to cerebral hyperperfusion syndrome after carotid artery revascularization in short term observation is similar regardless of the method used.


Assuntos
Angioplastia/efeitos adversos , Angioplastia/instrumentação , Estenose das Carótidas/terapia , Sistema Nervoso Central/fisiopatologia , Circulação Cerebrovascular , Transtornos Cerebrovasculares/etiologia , Endarterectomia das Carótidas/efeitos adversos , Stents , Sistema Nervoso Simpático/fisiopatologia , Idoso , Idoso de 80 Anos ou mais , Velocidade do Fluxo Sanguíneo , Estenose das Carótidas/diagnóstico , Estenose das Carótidas/fisiopatologia , Estenose das Carótidas/cirurgia , Transtornos Cerebrovasculares/diagnóstico , Transtornos Cerebrovasculares/fisiopatologia , Humanos , Pessoa de Meia-Idade , Exame Neurológico , Fluxo Sanguíneo Regional , Estudos Retrospectivos , Síndrome , Fatores de Tempo , Tomografia Computadorizada por Raios X , Resultado do Tratamento , Ultrassonografia Doppler Transcraniana
2.
Dis Esophagus ; 20(4): 358-60, 2007.
Artigo em Inglês | MEDLINE | ID: mdl-17617887

RESUMO

Esophageus or gaster resection in patients with malignant disease is still a treatment of choice. It is obvious that each surgical procedure in these patients carries some possibility of complications. Esophageo-gastric or esophageo-jejuno anastomosis has a 4-27% frequency of fistula occurrence. All these result in 65% mortality in cases of poorer prognosis. The aim of this paper is not to present all types of complications but to objectively analyse the usefulness of the covered stent placement in the treatment of anastomotic fistulas. We present six patients who were treated for postoperative fistula of esophageo-gastric anastomosis (1 case) or esophageo-jejuno anastomosis (5 cases). All patients were treated with stapler suture for digestive tract reconstruction after malignancy removal during the primary surgical procedure. Signs and symptoms of suture leak between 5-8 days post-surgery were observed. Conservative therapy was not effective. Thus a new method of treatment was employed - covered stent placement. The procedure was performed under X-ray control. In all treated patients there was change for the better and quick reduction of secretion from the fistulas was observed. All patients were discharged from the department after several days and all had survived at 30 days follow-up. Covered esophageal stent placement seems to be a safe and promising method of treatment for patients with anastomotic fistula which significantly reduces mortality and improves quality of live. Our experiences confirms that of other investigators.


Assuntos
Fístula Esofágica/cirurgia , Esofagostomia/efeitos adversos , Fístula Gástrica/cirurgia , Gastrostomia/efeitos adversos , Fístula Intestinal/cirurgia , Doenças do Jejuno/cirurgia , Jejunostomia/efeitos adversos , Stents , Fístula Esofágica/etiologia , Feminino , Fístula Gástrica/etiologia , Humanos , Fístula Intestinal/etiologia , Doenças do Jejuno/etiologia , Masculino , Pessoa de Meia-Idade , Desenho de Prótese
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