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1.
Soft Matter ; 19(23): 4376-4384, 2023 Jun 14.
Artigo em Inglês | MEDLINE | ID: mdl-37272395

RESUMO

We investigate the escape dynamics of oligochaeta Lumbriculus variegatus by confining them to a quasi-2D circular chamber with a narrow exit passage. The worms move by performing undulatory and peristaltic strokes and use their head to actively probe their surroundings. We show that the worms follow the chamber boundary with occasional reversals in direction and with velocities determined by the orientation angle of the body with respect to the boundary. The average time needed to reach the passage decreases with its width before approaching a constant, consistent with a boundary-following search strategy. We model the search dynamics as a persistent random walk along the boundary and demonstrate that the head increasingly skips over the passage entrance for smaller passage widths due to body undulations. The simulations capture the observed exponential time-distributions taken to reach the exit and their mean as a function of width when starting from random locations. Even after the head penetrates the passage entrance, we find that the worm does not always escape because the head withdraws rhythmically back into the chamber over distances set by the dual stroke amplitudes. Our study highlights the importance of boundary following and body strokes in determining how active matter escapes from enclosed spaces.

2.
BMC Pediatr ; 21(1): 168, 2021 04 09.
Artigo em Inglês | MEDLINE | ID: mdl-33836717

RESUMO

BACKGROUND: Community misperception on newborn care and poor treatment of sick newborn attributes to neonatal death and illness severity. Misperceptions and malpractices regarding neonatal care and neonatal complications are the leading causes of neonatal deaths in Bangladesh. The study was conducted to explore neonatal care's perceptions and practices and manage complications among Bangladesh's rural communities. METHODS: A qualitative study was conducted in Netrakona district of Bangladesh from April to June 2015. Three sub-districts (Upazilas) including Purbadhala, Durgapur and Atpara of Netrakona district were selected purposively. Five focus group discussions (FGDs) and twenty in-depth interviews (IDIs) were conducted in the rural community. Themes were identified through reading and re-reading the qualitative data and thematic analysis was performed. RESULTS: Community people were far behind, regarding the knowledge of neonatal complications. Most of them felt that the complications occurred due to lack of care by the parents. Some believed that mothers did not follow the religious customs after delivery, which affected the newborns. Many of them followed the practice of bathing the newborns and cutting their hair immediately after birth. The community still preferred to receive traditional treatment from their community, usually from Kabiraj (traditional healer), village doctor, or traditional birth attendant. Families also refrained from seeking treatment from the health facilities during neonatal complications. Instead, they preferred to wait until the traditional healers or village doctors recommended transferring the newborn. CONCLUSIONS: Poor knowledge, beliefs and practices are the key barriers to ensure the quality of care for the newborns during complications. The communities still depend on traditional practices and the level of demand for facility care is low. Appropriate interventions focusing on these issues might improve the overall neonatal mortality in Bangladesh.


Assuntos
Percepção , População Rural , Bangladesh , Feminino , Grupos Focais , Humanos , Recém-Nascido , Aceitação pelo Paciente de Cuidados de Saúde , Gravidez , Pesquisa Qualitativa
3.
Chaos ; 31(10): 103104, 2021 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-34717315

RESUMO

We explore the behavior of two coupled oscillators, considering combinations of similar and dissimilar oscillators, with their intrinsic dynamics ranging from periodic to chaotic. We first investigate the coupling of two different real-world systems, namely, the chemical mercury beating heart oscillator and the electronic Chua oscillator, with the disparity in the timescales of the constituent oscillators. Here, we are considering a physical situation that is not commonly addressed: the coupling of sub-systems whose characteristic timescales are very different. Our findings indicate that the oscillations in coupled systems are quenched to oscillation death (OD) state, at sufficiently high coupling strength, when there is a large timescale mismatch. In contrast, phase synchronization occurs when their timescales are comparable. In order to further strengthen the concept, we demonstrate this timescale-induced oscillation suppression and phase synchrony through numerical simulations, with the disparity in the timescales serving as a tuning or control parameter. Importantly, oscillation suppression (OD) occurs for a significantly smaller timescale mismatch when the coupled oscillators are chaotic. This suggests that the inherent broad spectrum of timescales underlying chaos aids oscillation suppression, as the temporal complexity of chaotic dynamics lends a natural heterogeneity to the timescales. The diversity of the experimental systems and numerical models we have chosen as a test-bed for the proposed concept lends support to the broad generality of our findings. Last, these results indicate the potential prevention of system failure by small changes in the timescales of the constituent dynamics, suggesting a potent control strategy to stabilize coupled systems to steady states.


Assuntos
Dinâmica não Linear
4.
Appl Soft Comput ; 109: 107540, 2021 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-34093096

RESUMO

The outbreak of COVID-19 had already shown its harmful impact on mankind, especially on health sectors, global economy, education systems, cultures, politics, and other important fields. Like most of the affected countries in the globe, India is now facing serious crisis due to COVID-19 in the recent times. The evaluation of the present status of the provinces affected by COVID-19 is very much essential to the government authorities to impose preventive strategies in controlling the spread of COVID-19 and to take necessary measures. In this article, a computational methodology is developed to estimate the present status of states and provinces which are affected due to COVID-19 using a fuzzy inference system. The factors such as population density, number of COVID-19 tests, confirmed cases of COVID-19, recovery rate, and mortality rate are considered as the input parameters of the proposed methodology. Considering positive and negative factors of the input parameters, the rule base is developed using triangular fuzzy numbers to capture uncertainties associated with the model. The application potentiality is validated by evaluating Pearson's correlation coefficient. A sensitivity analysis is also performed to observe the changes of final output by varying the tolerance ranges of the inputs. The results of the proposed method show that some of the provinces have very poor performance in controlling the spread of COVID-19 in India. So, the government needs to take serious attention to deal with the pandemic situation of COVID-19 in those provinces.

5.
Angew Chem Int Ed Engl ; 60(36): 19631-19636, 2021 Sep 01.
Artigo em Inglês | MEDLINE | ID: mdl-34010504

RESUMO

We report the discovery that simple carboxylic acids, such as benzoic acid, boost the activity of N-heterocyclic carbene (NHC) catalysts in the oxidative esterification of aldehydes. A simple and efficient protocol for the transformation of a wide range of sterically hindered α- and ß-substituted aliphatic aldehydes/enals, catalyzed by a novel and readily accessible N-Mes-/N-2,4,6-trichlorophenyl 1,2,4-triazolium salt, and benzoic acid as co-catalyst, was developed. A whole series of α/ß-substituted aliphatic aldehydes/enals hitherto not amenable to NHC-catalyzed esterification could be reacted at typical catalyst loadings of 0.02-1.0 mol %. For benzaldehyde, even 0.005 mol % of NHC catalyst proved sufficient: the lowest value ever achieved in NHC catalysis. Preliminary studies point to carboxylic acid-induced acceleration of acyl transfer from azolium enolate intermediates as the mechanistic basis of the observed effect.

6.
Angew Chem Int Ed Engl ; 60(9): 4507-4511, 2021 Feb 23.
Artigo em Inglês | MEDLINE | ID: mdl-33140529

RESUMO

Azolium enolates and acyl azolium cations have been proposed as intermediates in numerous N-heterocyclic carbene (NHC) catalyzed transformations. Acetyl azolium enolates were generated from the reaction of 2-propenyl acetate with both saturated (SIPr) and aromatic (IPr) NHCs, isolated, and characterized (NMR, XRD). Protonation with triflic acid gave the corresponding acetyl azolium triflates which were isolated and characterized (NMR, XRD). Acyl azolium cations have been proposed as immediate precursors of the ester product, for example, in the redox esterification of α,ß-enals. Studies with d3 -acetyl azolium triflate suggest that ester formation originates instead from an azolium enolate intermediate. Furthermore, the acetyl azolium enolate selectively reacted with alcohol nucleophiles in the presence of amines. While the acetyl azolium cation did not react with alcohols, an ester-selective reaction was induced by addition of base, by intermediate formation of the acetyl azolium enolate.

7.
Soft Matter ; 16(26): 6138-6144, 2020 Jul 08.
Artigo em Inglês | MEDLINE | ID: mdl-32555827

RESUMO

We experimentally study the stochastic transport of a self-propelled camphor boat, driven by Marangoni forces, through a crowd of passive paper discs floating on water. We analyze the statistics of the first passage times of the active particle to travel from the center of a circular container to its boundary. While the mean times rise monotonically as a function of the covered area fraction φ of the passive paper discs, their fluctuations show a non-monotonic behavior - being higher at low and high value of φ compared to intermediate values. The reason is traced to an interplay of two distinct sources of fluctuations - one intrinsic to the dynamics, while the other due to the crowding.

8.
BMC Public Health ; 19(1): 600, 2019 May 17.
Artigo em Inglês | MEDLINE | ID: mdl-31101099

RESUMO

BACKGROUND: Kamrangirchar and Hazaribagh are the largest slum areas in Dhaka, Bangladesh. In 2013, Médecins Sans Frontières initiated an urban healthcare programme in these areas providing services for factory workers and responding to the sexual and reproductive health needs of young women. Little in-depth information is available on perceptions of health and health seeking behaviour in this population. We aimed to provide a better understanding of community perceptions toward health and health care in order to inform programme strategies. METHODS: In-depth interviews were conducted with women (n = 13); factory workers (n = 14); and key informants (n = 13). Participants were selected using purposive maximum variation sampling and voluntarily consented to take part. Topic guides steered participant-led interviews, which were audio-recorded, translated and transcribed from Bangla into English. By comparing cases, we identified emerging themes, patterns and relationships in the data. NVivo11© was used to sort and code the data. RESULTS: Emerging themes indicated that in Kamrangirchar and Hazaribagh, health is seen as an asset necessary for work and, thus, for survival. Residents navigate a highly fragmented health system looking for 'quick fixes' to avoid time off work, with the local pharmacy deemed 'good enough' for 'common' health issues. Health care seeking for 'serious' conditions is characterised by uncertainty, confusion, and unsatisfactory results. Decisions are made communally and shaped by collective perceptions of quality care. People with limited socio-economic capital have few options for care. 'Quality care' is perceived as comprehensive care 'under one roof,' including predictive biomedical diagnostics and effective medication, delivered through a trusting relationship with the care provider. CONCLUSIONS: Health seeking behaviour of slum dwellers of Kamrangirchar and Hazaribagh is based on competing priorities, where quick and effective care is key, focussed on the ability to work and generate income. This takes place in a fragmented healthcare system characterised by mistrust of providers, and where navigation is informed by word-of-mouth experiences of peers. Improving health in this context demands a comprehensive and integrated approach to health care delivery, with an emphasis on rapid diagnosis, effective treatment and referral, and improved trust in care providers. Health education must be developed in collaboration with the community to identify knowledge gaps, support decision-making, and be channelled through existing networks. Further research should consider the effectiveness of interventions aiming to improve the practice of pharmacists.


Assuntos
Atitude Frente a Saúde , Aceitação pelo Paciente de Cuidados de Saúde/psicologia , Pobreza/psicologia , Trabalho/psicologia , Adulto , Bangladesh , Tomada de Decisões , Atenção à Saúde , Feminino , Humanos , Pessoa de Meia-Idade , Áreas de Pobreza , Relações Profissional-Paciente , Pesquisa Qualitativa , Confiança
9.
BMC Pregnancy Childbirth ; 18(1): 224, 2018 Jun 13.
Artigo em Inglês | MEDLINE | ID: mdl-29914393

RESUMO

BACKGROUND: An estimated 2.6 million stillbirths occur every year, with the majority occurring in low- and middle-income countries. Understanding the cause of and factors associated with stillbirth is important to help inform the design and implementation of interventions aimed at reducing preventable stillbirths. METHODS: Population-based surveillance with identification of all stillbirths that occurred either at home or in a health facility was introduced in four districts in Bangladesh. Verbal autopsy was conducted for every fifth stillbirth using a structured questionnaire. A hierarchical model was used to assign likely cause of stillbirth. RESULTS: Six thousand three hundred thirty-three stillbirths were identified for which 1327 verbal autopsies were conducted. 63.9% were intrapartum stillbirths. The population-based stillbirth rate obtained was 20.4 per 1000 births; 53.9% of all stillbirths occurred at home. 69.6% of mothers had accessed health care in the period leading up to the stillbirth. 48.1% had received care from a highly trained healthcare provider. The three most frequent causes of stillbirth were maternal hypertension or eclampsia (15.2%), antepartum haemorrhage (13.7%) and maternal infections (8.9%). Up to 11.3% of intrapartum stillbirths were caused by hypoxia. However, it was not possible to identify a cause of death with reasonable certainty using information obtained via verbal autopsy in 51.9% of stillbirths. CONCLUSIONS: Introducing surveillance for stillbirths at community level is possible. However, verbal autopsy yields limited data, and the questionnaire used for this needs to be revised and/or combined with information obtained through case note review. Most women accessed and received care from a qualified healthcare provider. To reduce the number of preventable stillbirths, the quality of antenatal and intrapartum care needs to be improved.


Assuntos
Instalações de Saúde/estatística & dados numéricos , Parto Domiciliar/estatística & dados numéricos , Vigilância da População , População Rural/estatística & dados numéricos , Natimorto/epidemiologia , Adolescente , Adulto , Autopsia , Bangladesh/epidemiologia , Feminino , Humanos , Gravidez , Adulto Jovem
10.
BMC Health Serv Res ; 18(1): 467, 2018 06 18.
Artigo em Inglês | MEDLINE | ID: mdl-29914495

RESUMO

BACKGROUND: Burns can be the most devastating injuries in the world, they constitute a global public health problem and cause widespread public health concern. Every year in Bangladesh more than 365,000 people are injured by electrical, thermal and other causes of burn injuries. Among them 27,000 need hospital admission and over 5600 people die. Immediate treatment and medication has been found to be significant in the success of recovering from a burn. However, common practices used in the treatment of burn injuries in the community is not well documented in Bangladesh. This study was designed to explore the perception of local communities in Bangladesh the common practices used and health-seeking behaviors sought immediately after a burn injury has occurred. METHODS: A qualitative study was conducted using Focus Group Discussions (FGD) as the data collection method. Six unions of three districts in rural Bangladesh were randomly selected and FGDs were conducted in these districts with six burn survivors and their relatives and neighbours. Data were analyzed manually, codes were identified and the grouped into themes. RESULTS: The participants stated that burn injuries are common during the winter in Bangladesh. Inhabitants in the rural areas said that it was common practice, and correct, to apply the following to the injured area immediately after a burn: egg albumin, salty water, toothpaste, kerosene, coconut oil, cow dung or soil. Some also believed that applying water is harmful to a burn injury. Most participants did not know about any referral system for burn patients. They expressed their dissatisfaction about the lack of available health service facilities at the recommended health care centers at both the district level and above. CONCLUSIONS: In rural Bangladesh, the current first-aid practices for burn injuries are incorrect; there is a widely held belief that using water on burns is harmful.


Assuntos
Queimaduras/terapia , Primeiros Socorros , Adulto , Idoso , Bangladesh/epidemiologia , Queimaduras/epidemiologia , Feminino , Primeiros Socorros/métodos , Primeiros Socorros/normas , Grupos Focais , Comportamentos Relacionados com a Saúde , Conhecimentos, Atitudes e Prática em Saúde , Necessidades e Demandas de Serviços de Saúde , Humanos , Masculino , Pessoa de Meia-Idade , Percepção , Pesquisa Qualitativa , População Rural , Adulto Jovem
11.
BMC Health Serv Res ; 16(1): 659, 2016 11 15.
Artigo em Inglês | MEDLINE | ID: mdl-27846877

RESUMO

BACKGROUND: Social autopsy is an innovative approach to explore social barriers and factors associated to a death in the community. The process also sensitize the community people to avert future deaths. Social autopsy has been introduced in maternal deaths in Bangladesh first time in 2010. This study is to identify the social factors in the rural community associated to maternal deaths. It also looks at how the community responses in social autopsy intervention to prevent future maternal deaths. METHODS: The study was conducted in the Thakurgaon district of Bangladesh in 2010. We have purposively selected 28 social autopsy cases of which maternal deaths occurred due to either haemorrhage or due to convulsions. The autopsy was conducted by the Government health and family planning first line field supervisors in rural community. Family members and neighbours of the deceased participated in each autopsy and provided their comments and responses. RESULTS: A number of social factors including delivery conducted by the untrained birth attendant or family members, delays in understanding about maternal complications, delays in decision making to transfer the mother, lack of proper knowledge, education and traditional myth influences the maternal deaths. The community identified their own problems, shared within them and decide upon rectify themselves for future death prevention. CONCLUSIONS: Social autopsy is a useful tools to identify social community within the community by discussing the factors that took place during a maternal death. The process supports villagers to think and change their behavioural patterns and commit towards preventing such deaths in the future.


Assuntos
Hemorragia/mortalidade , Complicações na Gravidez/mortalidade , Convulsões/mortalidade , Adolescente , Adulto , Autopsia , Bangladesh/epidemiologia , Causas de Morte , Feminino , Humanos , Morte Materna , Mortalidade Materna , Pessoa de Meia-Idade , Hemorragia Pós-Parto/mortalidade , Gravidez , Saúde da População Rural , Adulto Jovem
12.
ScientificWorldJournal ; 2015: 136434, 2015.
Artigo em Inglês | MEDLINE | ID: mdl-25954767

RESUMO

A tragic disaster occurred on April 24, 2013, in Bangladesh, when a nine storied building in a suburban area collapsed and killed 1115 people and injured many more. The study describes the process of rescue operation and emergency management services provided in the event. Data were collected using qualitative methods including in-depth interviews and a focus group discussion with the involved medical students, doctors, volunteers, and local people. Immediately after the disaster, rescue teams came to the place from Bangladesh Armed Forces, Bangladesh Navy, Bangladesh Air Force, and Dhaka Metropolitan and local Police and doctors, medical students, and nurses from nearby medical college hospitals and private hospitals and students from colleges and universities including local civil people. Doctors and medical students provided 24-hour services at the disaster place and in hospitals. Minor injured patients were treated at health camps and major injured patients were immediately carried to nearby hospital. Despite the limitations of a low resource setting, Bangladesh faced a tremendous challenge to manage the man-made disaster and experienced enormous support from different sectors of society to manage the disaster carefully and saved thousands of lives. This effort could help to develop a standard emergency management system applicable to Bangladesh and other counties with similar settings.


Assuntos
Desastres , Serviços Médicos de Emergência , Trabalho de Resgate , Colapso Estrutural , Bangladesh , Emergências , Humanos
13.
Phys Rev E ; 109(2-2): 025003, 2024 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-38491703

RESUMO

We investigate the elastic energy stored in a filament pair as a function of applied twist by measuring torque under prescribed end-to-end separation conditions. We show that the torque increases rapidly to a peak with applied twist when the filaments are initially separate, then decreases to a minimum as the filaments cross and come into contact. The torque then increases again while the filaments form a double helix with increasing twist. A nonlinear elasto-geometric model that combines the effect of geometrical nonlinearities with large stretching and self-twist is shown to capture the evolution of the helical geometry, torque profile, and stored energy with twist. We find that a large fraction of the total energy is stored in stretching the filaments, which increases with separation distance and applied tension. We find that only a small fraction of energy is stored in the form of bending energy, and that the contribution due to contact energy is negligible. Further, we provide analytical formulas for the torque observed as a function of the applied twist and the inverse relation of the observed angle for a given applied torque in the Hookean limit. Our study highlights the consequences of stretchablility on filament twisting, which is a fundamental topological transformation relevant to making ropes, tying shoelaces, actuating robots, and the physical properties of entangled polymers.

14.
J Midwifery Womens Health ; 68(3): 371-375, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-37255220

RESUMO

Sexual and reproductive health and rights (SRHR) is often a neglected topic of intervention in humanitarian crises despite its wide-ranging impact on women and girls' well-being. Increasing frequency of climate-induced natural disasters calls for an urgent need to identify innovative practices for sustainable and effective humanitarian preparedness and response to ensure SRHR of affected populations. One such innovation is the empowerment of midwives in disaster response program planning and implementation. This article describes how midwives deployed to rural primary health centers provided quality SRHR services, particularly for labor and birth assistance and initial management of perinatal emergencies and referral in the aftermath of the 2022 flooding in northern and northeastern Bangladesh. Supportive supervision from physicians, adequate health care logistics and supplies, and administrative support from local health authorities created an enabling environment for the midwives. Community engagement through volunteers helped build rapport with residents and allowed patients to navigate health services. Deploying midwives as a response to climate-induced natural disaster was successful in establishing quality SRHR services. Future recommendations include systematically deploying midwives in health centers closest to the communities in locations vulnerable to climate change as part of routine health service delivery. This innovative approach clearly demonstrated that utilization of midwives during and after natural disasters could build community and health system resilience to climate change.


Assuntos
Desastres , Tocologia , Socorro em Desastres , Serviços de Saúde Rural , Gravidez , Humanos , Feminino , Bangladesh
15.
Biomed Pharmacother ; 161: 114507, 2023 May.
Artigo em Inglês | MEDLINE | ID: mdl-36958194

RESUMO

Gold complexes could be promising for tumor therapy because of their cytotoxic and cytostatic properties. We present novel gold(I) complexes and clarify whether they also show antitumor activity by studying apoptosis induction in different tumor cell lines in vitro, comparing the compounds on resistant cells and analyzing the mechanism of action. We particularly highlight one gold complex that shows cytostatic and cytotoxic effects on leukemia and lymphoma cells already in the nanomolar range, induces apoptosis via the intrinsic signaling pathway, and plays a role in the production of reactive oxygen species. Furthermore, not only did we demonstrate a large number of resistance overcomes on resistant cell lines, but some of these cell lines were significantly more sensitive to the new gold compound. Our results show promising properties for the gold compound as anti-tumor drug and suggest that it can subvert resistance mechanisms and thus targets resistant cells for killing.


Assuntos
Antineoplásicos , Citostáticos , Leucemia , Linfoma , Humanos , Antineoplásicos/farmacologia , Antineoplásicos/uso terapêutico , Apoptose , Linhagem Celular Tumoral , Citostáticos/farmacologia , Resistência a Múltiplos Medicamentos , Resistencia a Medicamentos Antineoplásicos , Ouro/farmacologia , Leucemia/patologia , Linfoma/tratamento farmacológico , Espécies Reativas de Oxigênio/metabolismo , Regulação para Cima , Proteínas Reguladoras de Apoptose/metabolismo
16.
PLOS Glob Public Health ; 3(5): e0000786, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-37163506

RESUMO

From 2020, COVID-19 spread rapidly around the globe and continues to have a major impact on health system functioning, with a disproportionate impact on low- and middle-income countries (LMIC). Reduced service utilisation and coverage of essential childbirth interventions is likely impacting maternal and newborn morbidity and mortality. Telehealth has been identified as an important tool in the continued provision of essential healthcare services. The aim of this study was to explore the experience and impact of implementing telehealth services for the provision of remote antenatal (ANC) and postnatal (PNC) contacts in regions of Bangladesh and Lao People's Democratic Republic through 100 semi-structured interviews with health service leaders and providers, and childbearing women who organised, provided, or were the recipients of ANC and PNC telehealth during the COVID-19 pandemic response. The findings showed that a sudden pivot from face-to-face to telehealth services posed both health system and provision of care challenges. Health systems lacked funding to support telehealth and the infrastructure needed for service changes; however, some were able to work with key maternal child health departments within Ministries of Health to find the resources to implement the services. Health providers found telehealth beneficial during the pandemic response but identified a lack of training, guidance, and support as a barrier to changing practice. Childbearing women reported being fearful of accessing care at health services due to COVID-19, and whilst they appreciated the telehealth contacts, many continued to prefer face-to-face delivery of ANC and PNC care. Telehealth, however, was a good alternative in a time when face-to-face care was not possible. Considerations for post-pandemic broader implementation or scale-up of telehealth for routine antenatal and postnatal maternity care provision include the need for further research on issues such as accessibility, acceptability, quality of care, and sustainability of service provision.

17.
Phys Rev E ; 105(3): L032201, 2022 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-35428135

RESUMO

In this work, we report a quenching of oscillations observed upon coupling two chemomechanical oscillators. Each one of these oscillators consists of a drop of liquid metal submerged in an oxidizing solution. These pseudoidentical oscillators have been shown to exhibit both periodic and aperiodic oscillatory behavior. In the experiments performed on these oscillators, we find that coupling two such oscillators via an attenuated resistive coupling leads the coupled system towards an oscillation quenched state. To further comprehend these experimental observations, we numerically explore and verify the presence of similar oscillation quenching in a model of coupled Hindmarsh-Rose (HR) systems. A linear stability analysis of this HR system reveals that attenuated coupling induces a change in eigenvalues of the relevant Jacobian, leading to stable quenched oscillation states. Additionally, the analysis yields a threshold of attenuation for oscillation quenching that is consistent with the value observed in numerics. So this phenomenon, demonstrated through experiments, as well as simulations and analysis of a model system, suggests a powerful natural mechanism that can potentially suppress periodic and aperiodic oscillations in coupled nonlinear systems.

18.
Heliyon ; 8(3): e09156, 2022 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-35846460

RESUMO

Background: The emergency management of severe burn (EMSB) course is one of the widely taken courses in over 15 courses worldwide. In Bangladesh, the course has been running since 2008. Over 600 doctors and only 72 nurses participated in the EMSB courses in Bangladesh. The study explored the experiences of the EMSB course for the nurse, including opportunity and way forward. Methodology: A multi-method study was conducted. Quantitative data were collected from 54 nurses using the telephone interviews. In addition, one focus group discussion was performed with the EMSB faculty members to obtain qualitative information. Results: Out of 54 participant nurses, 47(87.04%) were female, and 7 (12.96%) were male. Almost two-thirds of nurses (62.96%) were working at medical colleges and hospitals. About 52% of the respondents stated that they had the opportunity to use the knowledge and skill acquired from EMSB training in managing burn patients. Those who had a chance to use the EMSB course knowledge, among them a vast majority (92.8%) mentioned that it helped manage severe burn patients. However, every nurse struggled with the course language. As a result, they were not able to qualify for the written course examination. They were also not able to interact well during the lecture sessions. However, nurses did well in the moulage practical simulation session. Conclusions: Immediate management of burn at the facility level could reduce disease burden, including hospital stay and quality of life. Nurses EMSB course, therefore, is essential for burn management in Bangladesh. Furthermore, course content updating, including bilingual option, could improve the nurse's course completion rate and confidence to contribute to their job areas.

19.
Sci Rep ; 12(1): 562, 2022 01 12.
Artigo em Inglês | MEDLINE | ID: mdl-35022493

RESUMO

Diabetes Distress (DD)-an emotional or affective state arise from challenge of living with diabetes and the burden of self-care-negatively impact diabetes management and quality of life of T2DM patients. Early detection and management of DD is key to efficient T2DM management. The study aimed at developing a valid and reliable instrument for Bangladeshi patients as unavailability such a tool posing challenge in diabetes care. Linguistically adapted, widely used, 17-item Diabetes Distress Scale (DDS), developed through forward-backward translation from English to Bengali, was administered on 1184 T2DM patients, from four diabetes hospitals in Bangladesh. Psychometric assessment of the instrument included, construct validity using principal component factor analysis, internal consistency using Cronbach's α and discriminative validity through independent t-test and test-retest reliability using intraclass-correlation coefficient (ICC) and Kappa statistics. Factor analysis extracted 4 components similar to original DDS domains, confirms the construct validity. The scale demonstrated satisfactory internal consistency (α = 0.838), stability (test-retest ICC = 0.941) and good agreement across repeated measurements (Kappa = 0.584). Discriminative validity revealed that patients with complication (p < 0.001) and those are on insulin (p < 0.001) had significantly higher distress scores in all domains. Bengali version of DDS is a valid and reliable tool for assessing distress among Bangladeshi T2DM patients.


Assuntos
Diabetes Mellitus Tipo 2/psicologia , Angústia Psicológica , Psicometria/estatística & dados numéricos , Adulto , Bangladesh , Feminino , Humanos , Masculino , Pessoa de Meia-Idade
20.
BMJ Open ; 11(3): e043298, 2021 03 19.
Artigo em Inglês | MEDLINE | ID: mdl-33741665

RESUMO

OBJECTIVE: To determine the prevalence of non-communicable disease (NCD) risk factors among nurses and para-health professionals (PHPs) working at primary healthcare centres in Bangladesh. In addition to this, we also investigated the association of these risk factors with the categories of health professions. DESIGN: Cross-sectional study and the sampling technique was a census. SETTING: The study site was a medical university of Bangladesh where the study population was recruited by NCD Control Programme of Directorate General of Health Services to participate in a 3-day training session from November 2017 to May 2018. PARTICIPANTS: A total of 1942 government-employed senior staff nurses (SSNs) and PHPs working at Upazila Health Complexes. PRIMARY AND SECONDARY OUTCOME MEASURES: The data were collected using a modified STEPwise approach to NCD risk factors surveillance questionnaire of the World Health Organisation (V.3.2). The prevalence of NCD risk factors was presented descriptively and the χ² test was used to determine the association between NCD risk factors distribution and categories of health professions. RESULTS: The mean age of the participants was 37.6 years (SD 9.5) and most of them (87.6%) had a diploma in their respective fields. Physical inactivity (86.9%), inadequate fruits and/vegetable intake (56.3%) and added salt intake (35.6%) were the most prevalent behavioural risk factors. The prevalence of central obesity, overweight, raised blood glucose and raised BP were 83.5%, 42.6%, 19.2% and 12.8% respectively. Overall, the NCD risk factors prevalence was higher among PHPs compared with SSNs. A highly significant association (p<0.001) was found between risk factors and the categories of health professions for tobacco use, alcohol intake, added salt intake and physical inactivity. CONCLUSION: High NCD risk factors prevalence and its significant association with SSNs and PHPs demand an appropriate risk-reduction strategy to minimise the possibility of chronic illness among them.


Assuntos
Hipertensão , Doenças não Transmissíveis , Adulto , Bangladesh/epidemiologia , Estudos Transversais , Humanos , Doenças não Transmissíveis/epidemiologia , Prevalência , Atenção Primária à Saúde , Fatores de Risco
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