Detalhe da pesquisa
1.
α-synuclein buildup is alleviated via ESCRT-dependent endosomal degradation brought about by p38MAPK inhibition in cells expressing p25α.
J Biol Chem
; 298(11): 102531, 2022 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-36162505
2.
The Structural Combination of SIL and MODAG Scaffolds Fails to Enhance Binding to α-Synuclein but Reveals Promising Affinity to Amyloid ß.
Molecules
; 28(10)2023 May 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37241742
3.
Key role of a structural water molecule for the specificity of 14F7-An antitumor antibody targeting the NeuGc GM3 ganglioside.
Glycobiology
; 31(11): 1500-1509, 2021 12 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-34735569
4.
Multiple system atrophy-associated oligodendroglial protein p25α stimulates formation of novel α-synuclein strain with enhanced neurodegenerative potential.
Acta Neuropathol
; 142(1): 87-115, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-33978813
5.
A proton wire and water channel revealed in the crystal structure of isatin hydrolase.
J Biol Chem
; 289(31): 21351-9, 2014 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24917679
6.
Characterization of pSer129-αSyn Pathology and Neurofilament Light-Chain Release across In Vivo, Ex Vivo, and In Vitro Models of Pre-Formed-Fibril-Induced αSyn Aggregation.
Cells
; 13(3)2024 Jan 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-38334646
7.
Perdeuterated GbpA Enables Neutron Scattering Experiments of a Lytic Polysaccharide Monooxygenase.
ACS Omega
; 8(32): 29101-29112, 2023 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37599915
8.
A Fluorescent Probe as a Lead Compound for a Selective α-Synuclein PET Tracer: Development of a Library of 2-Styrylbenzothiazoles and Biological Evaluation of [18F]PFSB and [18F]MFSB.
ACS Omega
; 8(34): 31450-31467, 2023 Aug 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-37663501
9.
Virus-like Immune Defense Protein in Mushrooms.
Structure
; 26(3): 369-371, 2018 03 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29514076
10.
A fundamental catalytic difference between zinc and manganese dependent enzymes revealed in a bacterial isatin hydrolase.
Sci Rep
; 8(1): 13104, 2018 08 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-30166577
11.
Soluble T-cell receptor design influences functional yield in an E. coli chaperone-assisted expression system.
PLoS One
; 13(4): e0195868, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29649333
12.
Crystal structure of an L chain optimised 14F7 anti-ganglioside Fv suggests a unique tumour-specificity through an unusual H-chain CDR3 architecture.
Sci Rep
; 8(1): 10836, 2018 Jul 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-30022069
13.
The crystal structure of the regulatory domain of the human sodium-driven chloride/bicarbonate exchanger.
Sci Rep
; 7(1): 12131, 2017 09 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-28935959
14.
Malonate in the nucleotide-binding site traps human AKAP18γ/δ in a novel conformational state.
Acta Crystallogr F Struct Biol Commun
; 72(Pt 8): 591-7, 2016 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-27487922
15.
Enzymatic detection and quantification assay of isatin, a putative stress biomarker in blood.
ACS Chem Neurosci
; 6(8): 1353-60, 2015 Aug 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-25891478
16.
The N-terminal cytoplasmic region of NCBE displays features of an intrinsic disordered structure and represents a novel target for specific drug screening.
Front Physiol
; 4: 320, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-24223558