Detalhe da pesquisa
1.
Electrochemical Detection of Small Molecule Induced Pseudomonas aeruginosa Biofilm Dispersion.
Electrochim Acta
; 268: 276-282, 2018 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30504968
2.
The Discovery of 2-Aminobenzimidazoles That Sensitize Mycobacterium smegmatis and M.â tuberculosis to ß-Lactam Antibiotics in a Pattern Distinct from ß-Lactamase Inhibitors.
Angew Chem Int Ed Engl
; 56(14): 3940-3944, 2017 03 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-28247991
3.
Novel Anti-virulence Compounds Disrupt Exotoxin Expression in MRSA.
bioRxiv
; 2024 May 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-38798408
4.
Loratadine Combats Methicillin-Resistant Staphylococcus aureus by Modulating Virulence, Antibiotic Resistance, and Biofilm Genes.
ACS Infect Dis
; 10(1): 232-250, 2024 Jan 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-38153409
5.
Programmable DNA-binding small molecules.
Bioorg Med Chem
; 21(20): 6101-14, 2013 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23665141
6.
Small Molecule Attenuates Bacterial Virulence by Targeting Conserved Response Regulator.
mBio
; 14(3): e0013723, 2023 06 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-37074183
7.
Functionalized Self-Assembled Monolayers: Versatile Strategies to Combat Bacterial Biofilm Formation.
Pharmaceutics
; 14(8)2022 Aug 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36015238
8.
Brominated Carbazole with Antibiotic Adjuvant Activity Displays Pleiotropic Effects in MRSA's Transcriptome.
ACS Chem Biol
; 17(5): 1239-1248, 2022 05 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-35467845
9.
Identification and Evaluation of Brominated Carbazoles as a Novel Antibiotic Adjuvant Scaffold in MRSA.
ACS Med Chem Lett
; 13(3): 483-491, 2022 Mar 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35295086
10.
Evaluation of small molecule kinase inhibitors as novel antimicrobial and antibiofilm agents.
Chem Biol Drug Des
; 98(6): 1038-1064, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34581492
11.
From Antihistamine to Anti-infective: Loratadine Inhibition of Regulatory PASTA Kinases in Staphylococci Reduces Biofilm Formation and Potentiates ß-Lactam Antibiotics and Vancomycin in Resistant Strains of Staphylococcus aureus.
ACS Infect Dis
; 5(8): 1397-1410, 2019 08 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-31132246
12.
Tricyclic amine antidepressants suppress ß-lactam resistance in methicillin-resistant Staphylococcus aureus (MRSA) by repressing mRNA levels of key resistance genes.
Chem Biol Drug Des
; 92(5): 1822-1829, 2018 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-29953721
13.
Resensitization of methicillin-resistant Staphylococcus aureus by amoxapine, an FDA-approved antidepressant.
Heliyon
; 4(1): e00501, 2018 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-29349359
14.
2-aminoimidazoles potentiate ß-lactam antimicrobial activity against Mycobacterium tuberculosis by reducing ß-lactamase secretion and increasing cell envelope permeability.
PLoS One
; 12(7): e0180925, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-28749949
15.
Membrane-permeabilizing activity of reverse-amide 2-aminoimidazole antibiofilm agents against Acinetobacter baumannii.
Curr Drug Deliv
; 12(2): 223-30, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-25348099
16.
Small-molecule inhibition of bacterial two-component systems to combat antibiotic resistance and virulence.
Future Med Chem
; 5(11): 1265-84, 2013 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-23859207
17.
Biologically inspired strategies for combating bacterial biofilms.
Curr Opin Pharmacol
; 13(5): 699-706, 2013 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-23871261