Detalhe da pesquisa
1.
Cryptococcus neoformans ADS lyase is an enzyme essential for virulence whose crystal structure reveals features exploitable in antifungal drug design.
J Biol Chem
; 292(28): 11829-11839, 2017 07 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-28559277
2.
Antifungal benzo[b]thiophene 1,1-dioxide IMPDH inhibitors exhibit pan-assay interference (PAINS) profiles.
Bioorg Med Chem
; 26(20): 5408-5419, 2018 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30322754
3.
Toward the establishment of standardized in vitro tests for lipid-based formulations. 5. Lipolysis of representative formulations by gastric lipase.
Pharm Res
; 32(4): 1279-87, 2015 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-25288015
4.
Toward the establishment of standardized in vitro tests for lipid-based formulations, part 3: understanding supersaturation versus precipitation potential during the in vitro digestion of type I, II, IIIA, IIIB and IV lipid-based formulations.
Pharm Res
; 30(12): 3059-76, 2013 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-23661145
5.
Purification, crystallization and preliminary X-ray analysis of adenylosuccinate synthetase from the fungal pathogen Cryptococcus neoformans.
Acta Crystallogr Sect F Struct Biol Cryst Commun
; 69(Pt 9): 1033-6, 2013 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-23989157
6.
Toward the establishment of standardized in vitro tests for lipid-based formulations. 2. The effect of bile salt concentration and drug loading on the performance of type I, II, IIIA, IIIB, and IV formulations during in vitro digestion.
Mol Pharm
; 9(11): 3286-300, 2012 Nov 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-23030411
7.
The Role of Titanium Dioxide (E171) and the Requirements for Replacement Materials in Oral Solid Dosage Forms: An IQ Consortium Working Group Review.
J Pharm Sci
; 111(11): 2943-2954, 2022 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-35973604
8.
Convergent microevolution of Cryptococcus neoformans hypervirulence in the laboratory and the clinic.
Sci Rep
; 7(1): 17918, 2017 12 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-29263343
9.
Disruption of de Novo Adenosine Triphosphate (ATP) Biosynthesis Abolishes Virulence in Cryptococcus neoformans.
ACS Infect Dis
; 2(9): 651-663, 2016 09 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-27759389
10.
Toward the establishment of standardized in vitro tests for lipid-based formulations, part 4: proposing a new lipid formulation performance classification system.
J Pharm Sci
; 103(8): 2441-55, 2014 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-24985238
11.
Toward the establishment of standardized in vitro tests for lipid-based formulations, part 6: effects of varying pancreatin and calcium levels.
AAPS J
; 16(6): 1344-57, 2014 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-25274609
12.
Characterization of the complete uric acid degradation pathway in the fungal pathogen Cryptococcus neoformans.
PLoS One
; 8(5): e64292, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23667704
13.
Toward the establishment of standardized in vitro tests for lipid-based formulations, part 1: method parameterization and comparison of in vitro digestion profiles across a range of representative formulations.
J Pharm Sci
; 101(9): 3360-80, 2012 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-22644939