Detalhe da pesquisa
1.
Organoid models of human and mouse ductal pancreatic cancer.
Cell
; 160(1-2): 324-38, 2015 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25557080
2.
Diabetes risk gene and Wnt effector Tcf7l2/TCF4 controls hepatic response to perinatal and adult metabolic demand.
Cell
; 151(7): 1595-607, 2012 Dec 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-23260145
3.
RNF43 truncations trap CK1 to drive niche-independent self-renewal in cancer.
EMBO J
; 39(18): e103932, 2020 09 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-32965059
4.
Long-term expanding human airway organoids for disease modeling.
EMBO J
; 38(4)2019 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30643021
5.
Correction: The Leukemia-Associated Mllt10/Af10-Dot1l Are Tcf4/ß-Catenin Coactivators Essential for Intestinal Homeostasis.
PLoS Biol
; 15(2): e1002596, 2017 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-28170393
6.
In vitro expansion of single Lgr5+ liver stem cells induced by Wnt-driven regeneration.
Nature
; 494(7436): 247-50, 2013 Feb 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-23354049
7.
Unlimited in vitro expansion of adult bi-potent pancreas progenitors through the Lgr5/R-spondin axis.
EMBO J
; 32(20): 2708-21, 2013 Oct 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-24045232
8.
Preclinical models of pancreatic ductal adenocarcinoma.
J Pathol
; 238(2): 197-204, 2016 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-26419819
9.
Centralized intestinal organoid generation is a feasible and safe approach for personalized medicine as demonstrated in the HIT-CF Europe Organoid Study.
J Cyst Fibros
; 2024 May 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-38763840
10.
Organoids as a biomarker for personalized treatment in metastatic colorectal cancer: drug screen optimization and correlation with patient response.
J Exp Clin Cancer Res
; 43(1): 61, 2024 Feb 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-38414064
11.
Repeatability and reproducibility of the Forskolin-induced swelling (FIS) assay on intestinal organoids from people with Cystic Fibrosis.
J Cyst Fibros
; 2024 May 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-38749892
12.
The leukemia-associated Mllt10/Af10-Dot1l are Tcf4/ß-catenin coactivators essential for intestinal homeostasis.
PLoS Biol
; 8(11): e1000539, 2010 Nov 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-21103407
13.
Epistasis of transcriptomes reveals synergism between transcriptional activators Hnf1alpha and Hnf4alpha.
PLoS Genet
; 6(5): e1000970, 2010 May 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-20523905
14.
Molecular and Functional Characterization of Human Intestinal Organoids and Monolayers for Modeling Epithelial Barrier.
Inflamm Bowel Dis
; 29(2): 195-206, 2023 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36356046
15.
Drug-repurposing screen on patient-derived organoids identifies therapy-induced vulnerability in KRAS-mutant colon cancer.
Cell Rep
; 42(4): 112324, 2023 04 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-37000626
16.
Intestinal organoids as an in vitro platform to characterize disposition, metabolism, and safety profile of small molecules.
Eur J Pharm Sci
; 188: 106481, 2023 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37244450
17.
Modeling resistance of colorectal peritoneal metastases to immune checkpoint blockade in humanized mice.
J Immunother Cancer
; 10(12)2022 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-36543378
18.
Engineering multicellular living systems-a Keystone Symposia report.
Ann N Y Acad Sci
; 1518(1): 183-195, 2022 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-36177947
19.
Functional patient-derived organoid screenings identify MCLA-158 as a therapeutic EGFR × LGR5 bispecific antibody with efficacy in epithelial tumors.
Nat Cancer
; 3(4): 418-436, 2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35469014
20.
Medium-Throughput Drug- and Radiotherapy Screening Assay using Patient-Derived Organoids.
J Vis Exp
; (170)2021 04 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-33999032