Detalhe da pesquisa
1.
Chemogenetics defines receptor-mediated functions of short chain free fatty acids.
Nat Chem Biol
; 15(5): 489-498, 2019 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30992568
2.
Treatment of Active Crohn's Disease With an Ordinary Food-based Diet That Replicates Exclusive Enteral Nutrition.
Gastroenterology
; 156(5): 1354-1367.e6, 2019 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-30550821
3.
CB2 cannabinoid receptor agonist enantiomers HU-433 and HU-308: An inverse relationship between binding affinity and biological potency.
Proc Natl Acad Sci U S A
; 112(28): 8774-9, 2015 Jul 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-26124120
4.
A Novel Allosteric Activator of Free Fatty Acid 2 Receptor Displays Unique Gi-functional Bias.
J Biol Chem
; 291(36): 18915-31, 2016 09 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-27385588
5.
Ligands at the Free Fatty Acid Receptors 2/3 (GPR43/GPR41).
Handb Exp Pharmacol
; 236: 17-32, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-27757758
6.
The Pharmacology and Function of Receptors for Short-Chain Fatty Acids.
Mol Pharmacol
; 89(3): 388-98, 2016 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-26719580
7.
CB(1) receptor allosteric modulators display both agonist and signaling pathway specificity.
Mol Pharmacol
; 83(2): 322-38, 2013 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-23160940
8.
Phosphorylation bar-coding of free fatty acid receptor 2 is generated in a tissue-specific manner.
Elife
; 122023 Dec 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-38085667
9.
Chemogenetics defines a short-chain fatty acid receptor gut-brain axis.
Elife
; 112022 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35229717
10.
Metabolic and inflammatory functions of short-chain fatty acid receptors.
Curr Opin Endocr Metab Res
; 16: 1-9, 2021 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-32835130
11.
Adaptation of NS cells growth and differentiation to high-throughput screening-compatible plates.
BMC Neurosci
; 11: 7, 2010 Jan 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-20085655
12.
In vitro and in vivo pharmacological characterization of two novel selective cannabinoid CB(2) receptor inverse agonists.
Pharmacol Res
; 61(4): 349-54, 2010 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-19961936
13.
On-target and off-target effects of novel orthosteric and allosteric activators of GPR84.
Sci Rep
; 9(1): 1861, 2019 02 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30755705
14.
Discovery of a Potent Thiazolidine Free Fatty Acid Receptor 2 Agonist with Favorable Pharmacokinetic Properties.
J Med Chem
; 61(21): 9534-9550, 2018 11 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-30247908
15.
A single extracellular amino acid in Free Fatty Acid Receptor 2 defines antagonist species selectivity and G protein selection bias.
Sci Rep
; 7(1): 13741, 2017 10 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-29061999
16.
Cannabidiol, a non-psychoactive cannabinoid compound, inhibits proliferation and invasion in U87-MG and T98G glioma cells through a multitarget effect.
PLoS One
; 8(10): e76918, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-24204703
17.
AM630 behaves as a protean ligand at the human cannabinoid CB2 receptor.
Br J Pharmacol
; 165(8): 2561-74, 2012 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-21615724
18.
Investigations on the 4-quinolone-3-carboxylic acid motif. 6. Synthesis and pharmacological evaluation of 7-substituted quinolone-3-carboxamide derivatives as high affinity ligands for cannabinoid receptors.
Eur J Med Chem
; 58: 30-43, 2012 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-23085772
19.
Investigations on the 4-quinolone-3-carboxylic acid motif part 5: modulation of the physicochemical profile of a set of potent and selective cannabinoid-2 receptor ligands through a bioisosteric approach.
ChemMedChem
; 7(5): 920-34, 2012 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-22383251
20.
Structural and pharmacological analysis of O-2050, a putative neutral cannabinoid CB(1) receptor antagonist.
Eur J Pharmacol
; 651(1-3): 96-105, 2011 Jan 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-21114999