Detalhe da pesquisa
1.
Unprecedented reactivity of polyamines with aldehydic DNA modifications: structural determinants of reactivity, characterization and enzymatic stability of adducts.
Nucleic Acids Res
; 51(20): 10846-10866, 2023 11 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37850658
2.
Light-Activatable Photocaged UNC2025 for Triggering TAM Kinase Inhibition in Bladder Cancer.
Chembiochem
; 25(8): e202300855, 2024 Apr 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-38363151
3.
A G-quadruplex-binding platinum complex induces cancer mitochondrial dysfunction through dual-targeting mitochondrial and nuclear G4 enriched genome.
J Biomed Sci
; 31(1): 50, 2024 May 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-38741159
4.
Photoactivatable V-Shaped Bifunctional Quinone Methide Precursors as a New Class of Selective G-quadruplex Alkylating Agents.
Chemistry
; 28(35): e202200734, 2022 Jun 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-35441438
5.
Nucleolin Discriminates Drastically between Long-Loop and Short-Loop Quadruplexes.
Biochemistry
; 59(12): 1261-1272, 2020 03 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-32191439
6.
Interaction of Functionalized Naphthalenophanes with Abasic Sites in DNA: DNA Cleavage, DNA Cleavage Inhibition, and Formation of Ligand-DNA Adducts.
Chemistry
; 25(8): 1949-1962, 2019 Feb 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-30508326
7.
Probing ligand and cation binding sites in G-quadruplex nucleic acids by mass spectrometry and electron photodetachment dissociation sequencing.
Analyst
; 144(11): 3518-3524, 2019 Jun 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-31020955
8.
Selectivity of Terpyridine Platinum Anticancer Drugs for G-quadruplex DNA.
Molecules
; 24(3)2019 01 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-30678027
9.
Platinum Complexes Can Bind to Telomeres by Coordination.
Int J Mol Sci
; 19(7)2018 Jul 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29970863
10.
Association of a Platinum Complex to a G-Quadruplex Ligand Enhances Telomere Disruption.
Chem Res Toxicol
; 30(8): 1629-1640, 2017 08 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-28657713
11.
Identification of human telomerase assembly inhibitors enabled by a novel method to produce hTERT.
Nucleic Acids Res
; 43(15): e99, 2015 Sep 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-25958399
12.
Linking of Antitumor trans NHC-Pt(II) Complexes to G-Quadruplex DNA Ligand for Telomeric Targeting.
Bioconjug Chem
; 27(6): 1456-70, 2016 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27115175
13.
Insights into the structure-activity relationships of chiral 1,2-diaminophenylalkane platinum(II) anticancer derivatives.
J Biol Inorg Chem
; 20(5): 841-53, 2015 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-25982100
14.
Interactions of Pt-ttpy with G-Quadruplexes Originating from Promoter Region of the c-myc Gene Deciphered by NMR and Gel Electrophoresis Analysis.
Chemistry
; 21(21): 7798-807, 2015 May 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-25847573
15.
Photo-cross-linking probes for trapping G-quadruplex DNA.
Angew Chem Int Ed Engl
; 53(4): 994-8, 2014 Jan 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-24338872
16.
Study of the synthesis, antiproliferative properties, and interaction with DNA and polynucleotides of cisplatin-like Pt(II) complexes containing carcinogenic polyaromatic amines.
J Biol Inorg Chem
; 18(7): 791-801, 2013 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-23873259
17.
Anti-Cancer and Radio-Sensitizing Properties of New Bimetallic (N-Heterocyclic Carbene)-Amine-Pt(II) Complexes.
J Med Chem
; 66(10): 6836-6848, 2023 05 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-37191470
18.
Acridine-O6-benzylguanine hybrids: Synthesis, DNA binding, MGMT inhibition and antiproliferative activity.
Eur J Med Chem
; 227: 113909, 2022 Jan 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-34731767
19.
Pt-ttpy, a G-quadruplex binding platinum complex, induces telomere dysfunction and G-rich regions DNA damage.
Metallomics
; 13(6)2021 06 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34021581
20.
Platination of telomeric DNA by cisplatin disrupts recognition by TRF2 and TRF1.
J Biol Inorg Chem
; 15(5): 641-54, 2010 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-20191372