Detalhe da pesquisa
1.
Configurational reassignment and improved preparation of the competitive IL-6 receptor antagonist 20R,21R-epoxyresibufogenin-3-formate.
J Nat Prod
; 75(4): 661-8, 2012 Apr 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-22360661
2.
Design and synthesis of promiscuous high-affinity monoamine transporter ligands: unraveling transporter selectivity.
J Med Chem
; 49(5): 1766-72, 2006 Mar 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-16509591
3.
In vivo evaluation of [123I]-4-(2-(bis(4-fluorophenyl)methoxy)ethyl)-1-(4-iodobenzyl)piperidine, an iodinated SPECT tracer for imaging the P-gp transporter.
Nucl Med Biol
; 37(4): 469-77, 2010 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-20447559
4.
Reversal of pancreatitis-induced pain by an orally available, small molecule interleukin-6 receptor antagonist.
Pain
; 151(2): 257-265, 2010 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-20599324
5.
3-O-Formyl-20R,21-epoxyresibufogenin suppresses IL-6-type cytokine actions by targeting the glycoprotein 130 subunit: potential clinical implications.
J Allergy Clin Immunol
; 120(2): 437-44, 2007 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-17451794
6.
DAT/SERT selectivity of flexible GBR 12909 analogs modeled using 3D-QSAR methods.
Bioorg Med Chem
; 15(2): 1146-59, 2007 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-17127069
7.
Structure-activity relationships of substituted N-benzyl piperidines in the GBR series: Synthesis of 4-(2-(bis(4-fluorophenyl)methoxy)ethyl)-1-(2-trifluoromethylbenzyl)piperidine, an allosteric modulator of the serotonin transporter.
Bioorg Med Chem
; 14(11): 3967-73, 2006 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-16563775
8.
Studies of the biogenic amine transporters. XI. Identification of a 1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazine (GBR12909) analog that allosterically modulates the serotonin transporter.
J Pharmacol Exp Ther
; 314(2): 906-15, 2005 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-15860577