Detalhe da pesquisa
1.
Directional ΔG Neural Network (DrΔG-Net): A Modular Neural Network Approach to Binding Free Energy Prediction.
J Chem Inf Model
; 64(6): 1907-1918, 2024 Mar 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-38470995
2.
On Ternary Complex Stability in Protein Degradation: In Silico Molecular Glue Binding Affinity Calculations.
J Chem Inf Model
; 63(8): 2382-2392, 2023 04 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-37037192
3.
Crystal structure of the GLP-1 receptor bound to a peptide agonist.
Nature
; 546(7657): 254-258, 2017 06 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-28562585
4.
Corrigendum: Crystal structure of the GLP-1 receptor bound to a peptide agonist.
Nature
; 548(7665): 122, 2017 08 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-28700581
5.
Extra-helical binding site of a glucagon receptor antagonist.
Nature
; 533(7602): 274-7, 2016 05 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-27111510
6.
Deconstructing the Pharmacological Contribution of Sphingosine-1 Phosphate Receptors to Mouse Models of Multiple Sclerosis Using the Species Selectivity of Ozanimod, a Dual Modulator of Human Sphingosine 1-Phosphate Receptor Subtypes 1 and 5.
J Pharmacol Exp Ther
; 379(3): 386-399, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34535564
7.
Mechanical thrombectomy in a pediatric patient with sedation aided by contralateral intra-arterial propofol injection: feasibility in an extreme condition.
Childs Nerv Syst
; 37(5): 1785-1789, 2021 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32856130
8.
Continuous stellate ganglion block in delayed cerebral ischemia: A possible supplementary approach to traditional therapy?
J Anaesthesiol Clin Pharmacol
; 36(2): 265-267, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-33013046
9.
Identification of a novel allosteric GLP-1R antagonist HTL26119 using structure- based drug design.
Bioorg Med Chem Lett
; 29(20): 126611, 2019 10 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31447084
10.
Reaction-Based Enumeration, Active Learning, and Free Energy Calculations To Rapidly Explore Synthetically Tractable Chemical Space and Optimize Potency of Cyclin-Dependent Kinase 2 Inhibitors.
J Chem Inf Model
; 59(9): 3782-3793, 2019 09 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-31404495
11.
Structure of class B GPCR corticotropin-releasing factor receptor 1.
Nature
; 499(7459): 438-43, 2013 Jul 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-23863939
12.
GPCR-Bench: A Benchmarking Set and Practitioners' Guide for G Protein-Coupled Receptor Docking.
J Chem Inf Model
; 56(4): 642-51, 2016 04 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-26958710
13.
Decoding the Role of Water Dynamics in Ligand-Protein Unbinding: CRF1R as a Test Case.
J Chem Inf Model
; 55(9): 1857-66, 2015 Sep 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-26335976
14.
Water network perturbation in ligand binding: adenosine A(2A) antagonists as a case study.
J Chem Inf Model
; 53(7): 1700-13, 2013 Jul 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-23725291
15.
The perils of dental vacation: possible anaesthetic and medicolegal consequences.
Med Sci Law
; 53(1): 19-23, 2013 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-23065683
16.
Thoracic epidural analgesia for type B aortic dissection.
J Anaesthesiol Clin Pharmacol
; 33(2): 260-261, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-28781458
17.
Competitive Binding of Ozanimod and Other Sphingosine 1-Phosphate Receptor Modulators at Receptor Subtypes 1 and 5.
Front Pharmacol
; 13: 892097, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35784713
18.
Novel Macrocyclic Antagonists of the Calcitonin Gene-Related Peptide Receptor: Design, Realization, and Structural Characterization of Protein-Ligand Complexes.
ACS Chem Neurosci
; 13(6): 751-765, 2022 03 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-35245037
19.
Making structural sense of dimerization interfaces of delta opioid receptor homodimers.
Biochemistry
; 50(10): 1682-90, 2011 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21261298
20.
Carbazole-containing arylcarboxamides as BACE1 inhibitors.
Bioorg Med Chem Lett
; 21(22): 6657-61, 2011 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21986588