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Comput Biol Med ; 167: 107635, 2023 12.
Artigo em Inglês | MEDLINE | ID: mdl-37952306

RESUMO

This study aims to examine geometric models of the corneal surface that can be used to reduce in reasonable time the dimensionality of datasets of normal anterior corneas. Polynomial models (P) like Zernike polynomials (ZP) and spherical harmonic polynomials (SHP) were obvious candidates along with their rational function (R) counterparts, namely Zernike rational functions (ZR) and spherical harmonic rational functions (SHR, new model). Knowing that both SHP and ZR were more accurate than ZP for the modeling of normal and keratoconus corneas, it was expected that both spherical harmonic (SH) models (SHP and SHR) would be more accurate than their Zernike (Z) counterparts (ZP and ZR, respectively), and both rational (R) models (SHR and ZR) more accurate than their polynomial counterparts (SHP and ZP, respectively) for a low dimensional space (coefficient number J < 30). This was the case. The SH factor contributed more to accuracy than the R factor. Considering the corneal processing time as a function of J, P models were processed in quasi-linear time with a quasi-null slope and rational models in polynomial time. Z models were faster than SH models, and increasingly so in their R version. In sum, for corneal dimensionality reduction, SHR is the most accurate model, but its processing time is increasingly prohibitive unless the best coefficient combination is identified beforehand. ZP is the fastest model and is reasonably accurate with normal corneas for exploratory tasks. SHP is the best compromise between accuracy and speed.


Assuntos
Córnea , Ceratocone , Humanos , Topografia da Córnea/métodos , Algoritmos , Modelos Estatísticos
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