Detalhe da pesquisa
1.
Profiling rhythmicity of bile salt hydrolase activity in the gut lumen with a rapid fluorescence assay.
Org Biomol Chem
; 21(19): 4028-4038, 2023 05 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-36810586
2.
AI-Accelerated Design of Targeted Covalent Inhibitors for SARS-CoV-2.
J Chem Inf Model
; 63(5): 1438-1453, 2023 03 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-36808989
3.
Integrated data-driven and experimental approaches to accelerate lead optimization targeting SARS-CoV-2 main protease.
J Comput Aided Mol Des
; 37(8): 339-355, 2023 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37314632
4.
Profiling How the Gut Microbiome Modulates Host Xenobiotic Metabolism in Response to Benzo[a]pyrene and 1-Nitropyrene Exposure.
Chem Res Toxicol
; 35(4): 585-596, 2022 04 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-35347982
5.
Activity-Based Protein Profiling of Bile Salt Hydrolysis in the Human Gut Microbiome with Beta-Lactam or Acrylamide-Based Probes.
Chembiochem
; 22(8): 1448-1455, 2021 04 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-33314683
6.
Simple Analysis of Primary and Secondary Bile Salt Hydrolysis in Mouse and Human Gut Microbiome Samples by Using Fluorogenic Substrates.
Chembiochem
; 21(24): 3539-3543, 2020 12 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32761683
7.
Bile salt hydrolase profiling by fluorogenic probes in the human gut microbiome.
Methods Enzymol
; 664: 243-265, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35331377
8.
Who Is Metabolizing What? Discovering Novel Biomolecules in the Microbiome and the Organisms Who Make Them.
Front Cell Infect Microbiol
; 10: 388, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32850487
9.
A continuous fluorescence assay for simple quantification of bile salt hydrolase activity in the gut microbiome.
Sci Rep
; 9(1): 1359, 2019 02 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30718677
10.
Conformation-Selective Analogues of Dasatinib Reveal Insight into Kinase Inhibitor Binding and Selectivity.
ACS Chem Biol
; 11(5): 1296-304, 2016 05 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-26895387
11.
UM-164: A Potent c-Src/p38 Kinase Inhibitor with In Vivo Activity against Triple-Negative Breast Cancer.
Clin Cancer Res
; 22(20): 5087-5096, 2016 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27154914
12.
The Chemical Biology of Molecular Chaperones--Implications for Modulation of Proteostasis.
J Mol Biol
; 427(18): 2931-47, 2015 Sep 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-26003923
13.
Exquisitely specific bisubstrate inhibitors of c-Src kinase.
ACS Chem Biol
; 10(6): 1387-91, 2015 Jun 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-25793938
14.
Retraction: UM-164: A Potent c-Src/p38 Kinase Inhibitor with In Vivo Activity against Triple-Negative Breast Cancer.
Clin Cancer Res
; 26(7): 1777, 2020 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32238414
15.
Development of a chimeric c-Src kinase and HDAC inhibitor.
ACS Med Chem Lett
; 4(8): 779-783, 2013 Aug 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-24015327
16.
Development of a highly selective c-Src kinase inhibitor.
ACS Chem Biol
; 7(8): 1393-8, 2012 Aug 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-22594480