Detalhe da pesquisa
1.
Monocyte NLRP3 inflammasome and interleukin-1ß activation modulated by alpha-1 antitrypsin therapy in deficient individuals.
Thorax
; 2024 Feb 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-38418195
2.
Lung Inflammation in alpha-1-antitrypsin deficient individuals with normal lung function.
Respir Res
; 24(1): 40, 2023 Feb 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36732772
3.
Chemokine signaling axis between endothelial and myeloid cells regulates development of pulmonary hypertension associated with pulmonary fibrosis and hypoxia.
Am J Physiol Lung Cell Mol Physiol
; 317(4): L434-L444, 2019 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31364370
4.
Analysis of the MILES cohort reveals determinants of disease progression and treatment response in lymphangioleiomyomatosis.
Eur Respir J
; 53(4)2019 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30846465
5.
Transcription factor Bcl11b sustains iNKT1 and iNKT2 cell programs, restricts iNKT17 cell program, and governs iNKT cell survival.
Proc Natl Acad Sci U S A
; 113(27): 7608-13, 2016 07 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-27330109
6.
Myeloid-derived Suppressor Cells Are Necessary for Development of Pulmonary Hypertension.
Am J Respir Cell Mol Biol
; 58(2): 170-180, 2018 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-28862882
7.
Whole-Genome Sequencing in Severe Chronic Obstructive Pulmonary Disease.
Am J Respir Cell Mol Biol
; 59(5): 614-622, 2018 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-29949718
8.
MZ Alpha-1 Antitrypsin Deficiency.
Am J Respir Crit Care Med
; 205(7): P13-P14, 2022 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35361070
9.
Alpha-1 Antitrypsin-Deficient Macrophages Have Increased Matriptase-Mediated Proteolytic Activity.
Am J Respir Cell Mol Biol
; 57(2): 238-247, 2017 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-28362108
10.
Bioequivalence of a Liquid Formulation of Alpha1-Proteinase Inhibitor Compared with Prolastin®-C (Lyophilized Alpha1-PI) in Alpha1-Antitrypsin Deficiency.
COPD
; 14(6): 590-596, 2017 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-28985109
11.
Genome-wide study of percent emphysema on computed tomography in the general population. The Multi-Ethnic Study of Atherosclerosis Lung/SNP Health Association Resource Study.
Am J Respir Crit Care Med
; 189(4): 408-18, 2014 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24383474
12.
Efficacy and safety of sirolimus in lymphangioleiomyomatosis.
N Engl J Med
; 364(17): 1595-606, 2011 Apr 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-21410393
13.
Serum Vascular Endothelial Growth Factor D in Cystic Lung Disease.
JAMA
; 321(4): 401-402, 2019 Jan 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-30605217
14.
Safety and pharmacokinetics of 120 mg/kg versus 60 mg/kg weekly intravenous infusions of alpha-1 proteinase inhibitor in alpha-1 antitrypsin deficiency: a multicenter, randomized, double-blind, crossover study (SPARK).
COPD
; 10(6): 687-95, 2013 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-23862647
15.
Novel SERPINA1 Alleles Identified through a Large Alpha-1 Antitrypsin Deficiency Screening Program and Review of Known Variants.
Chronic Obstr Pulm Dis
; 10(1): 7-21, 2023 Jan 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-36367950
16.
Multiplexing AAV Serotype-Specific Neutralizing Antibodies in Preclinical Animal Models and Humans.
Biomedicines
; 11(2)2023 Feb 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-36831059
17.
Development of a risk score to increase detection of severe alpha-1 antitrypsin deficiency.
ERJ Open Res
; 9(5)2023 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-37727673
18.
Association of IREB2 and CHRNA3 polymorphisms with airflow obstruction in severe alpha-1 antitrypsin deficiency.
Respir Res
; 13: 16, 2012 Feb 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-22356581
19.
Sustained transgene expression despite T lymphocyte responses in a clinical trial of rAAV1-AAT gene therapy.
Proc Natl Acad Sci U S A
; 106(38): 16363-8, 2009 Sep 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-19706466
20.
The prevalence of alpha-1 antitrypsin deficiency among patients found to have airflow obstruction.
COPD
; 9(4): 352-8, 2012 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-22506682