Detalhe da pesquisa
1.
Tetrameric c-di-GMP mediates effective transcription factor dimerization to control Streptomyces development.
Cell
; 158(5): 1136-1147, 2014 Aug 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-25171413
2.
Structural Basis for Virulence Activation of Francisella tularensis.
Mol Cell
; 81(1): 139-152.e10, 2021 01 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-33217319
3.
c-di-GMP Arms an Anti-σ to Control Progression of Multicellular Differentiation in Streptomyces.
Mol Cell
; 77(3): 586-599.e6, 2020 02 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-31810759
4.
A Predictive Model of Vaccine Reactogenicity Using Data from an In Vitro Human Innate Immunity Assay System.
J Immunol
; 212(5): 904-916, 2024 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38276072
5.
Dissection of the molecular circuitry controlling virulence in Francisella tularensis.
Genes Dev
; 31(15): 1549-1560, 2017 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28864445
6.
The nucleotide messenger (p)ppGpp is an anti-inducer of the purine synthesis transcription regulator PurR in Bacillus.
Nucleic Acids Res
; 50(2): 847-866, 2022 01 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-34967415
7.
Evolution of a σ-(c-di-GMP)-anti-σ switch.
Proc Natl Acad Sci U S A
; 118(30)2021 07 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-34290147
8.
Structures of Neisseria gonorrhoeae MtrR-operator complexes reveal molecular mechanisms of DNA recognition and antibiotic resistance-conferring clinical mutations.
Nucleic Acids Res
; 49(7): 4155-4170, 2021 04 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-33784401
9.
Crystal structure of an Escherichia coli Hfq Core (residues 2-69)-DNA complex reveals multifunctional nucleic acid binding sites.
Nucleic Acids Res
; 48(7): 3987-3997, 2020 04 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-32133526
10.
Glutathione activates virulence gene expression of an intracellular pathogen.
Nature
; 517(7533): 170-3, 2015 Jan 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-25567281
11.
HipBA-promoter structures reveal the basis of heritable multidrug tolerance.
Nature
; 524(7563): 59-64, 2015 Aug 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-26222023
12.
Optimization of a Noncanonical Anti-infective: Interrogation of the Target Binding Pocket for a Small-Molecule Inhibitor of Escherichia coli Polysaccharide Capsule Expression.
Antimicrob Agents Chemother
; 65(1)2020 12 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-33077659
13.
Tackling health emergencies in complex settings: the role of national public health institutes in the Eastern Mediterranean region.
Lancet
; 403(10421): 8-10, 2024 Jan 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-38081194
14.
Structural, Biochemical, and In Vivo Characterization of MtrR-Mediated Resistance to Innate Antimicrobials by the Human Pathogen Neisseria gonorrhoeae.
J Bacteriol
; 201(20)2019 10 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31331979
15.
Health can contribute to peace in the Eastern Mediterranean Region-what should be done to make it happen?
Lancet
; 402(10413): 1601-1603, 2023 11 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-37689076
16.
The Streptomyces master regulator BldD binds c-di-GMP sequentially to create a functional BldD2-(c-di-GMP)4 complex.
Nucleic Acids Res
; 45(11): 6923-6933, 2017 Jun 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-28449057
17.
Structures of trehalose-6-phosphate phosphatase from pathogenic fungi reveal the mechanisms of substrate recognition and catalysis.
Proc Natl Acad Sci U S A
; 113(26): 7148-53, 2016 06 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-27307435
18.
Responding to health emergencies in the Eastern Mediterranean region in times of conflict.
Lancet
; 399(10332): e20-e22, 2022 04 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-32135078
19.
Preparing for future pandemics in the Eastern Mediterranean region.
Lancet
; 399(10329): 1032-1033, 2022 03 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34895469
20.
New COVID-19 resurgence in the WHO Eastern Mediterranean region.
Lancet
; 397(10282): 1348-1349, 2021 04 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-33773609