Detalhe da pesquisa
1.
Acute inhibition of 11beta-hydroxysteroid dehydrogenase type-1 improves memory in rodent models of cognition.
J Neurosci
; 31(14): 5406-13, 2011 Apr 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-21471376
2.
Pharmacological properties and procognitive effects of ABT-288, a potent and selective histamine H3 receptor antagonist.
J Pharmacol Exp Ther
; 343(1): 233-45, 2012 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-22815533
3.
PARP inhibitors attenuate chemotherapy-induced painful neuropathy.
J Peripher Nerv Syst
; 17(3): 324-30, 2012 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-22971094
4.
Design, synthesis and evaluation of constrained tetrahydroimidazopyrimidine derivatives as antagonists of corticotropin-releasing factor type 1 receptor (CRF1R).
Bioorg Med Chem Lett
; 20(6): 1905-9, 2010 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20185312
5.
Synthesis, potency, and in vivo profiles of quinoline containing histamine H3 receptor inverse agonists.
J Med Chem
; 50(22): 5439-48, 2007 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-17918921
6.
Novel heterocyclic-substituted benzofuran histamine H3 receptor antagonists: in vitro properties, drug-likeness, and behavioral activity.
Biochem Pharmacol
; 73(8): 1243-55, 2007 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-17371699
7.
The drug-induced helplessness test: an animal assay for assessing behavioral despair in response to neuroleptic treatment.
Psychopharmacology (Berl)
; 190(1): 1-11, 2007 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-17093979
8.
Effect of dopamine D3 antagonists on PPI in DBA/2J mice or PPI deficit induced by neonatal ventral hippocampal lesions in rats.
Neuropsychopharmacology
; 31(7): 1382-92, 2006 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-16395300
9.
Effects of histamine H3 receptor antagonists in two models of spatial learning.
Behav Brain Res
; 159(2): 295-300, 2005 Apr 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-15817192
10.
A-412997, a selective dopamine D4 agonist, improves cognitive performance in rats.
Pharmacol Biochem Behav
; 82(1): 148-55, 2005 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-16154186
11.
H3 receptor blockade by thioperamide enhances cognition in rats without inducing locomotor sensitization.
Psychopharmacology (Berl)
; 167(4): 363-72, 2003 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-12682709
12.
Enhancement of prepulse inhibition of startle in mice by the H3 receptor antagonists thioperamide and ciproxifan.
Behav Brain Res
; 153(1): 69-76, 2004 Aug 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-15219708
13.
Assessment of the abuse liability of ABT-288, a novel histamine H3 receptor antagonist.
Psychopharmacology (Berl)
; 228(2): 187-97, 2013 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-23455597
14.
Behavioral characterization of a mutant mouse strain lacking D-amino acid oxidase activity.
Behav Brain Res
; 217(1): 81-7, 2011 Feb 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-20933022
15.
ABT-594 improves performance in the 5-choice serial reaction time task under conditions of increased difficulty, sub-chronic dosing, and in poorly-performing subjects.
Pharmacol Biochem Behav
; 95(2): 146-57, 2010 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-20064548
16.
Mice expressing the Swedish APP mutation on a 129 genetic background demonstrate consistent behavioral deficits and pathological markers of Alzheimer's disease.
Brain Res
; 1311: 136-47, 2010 Jan 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-19944081
17.
The alkaloid conessine and analogues as potent histamine H3 receptor antagonists.
J Med Chem
; 51(17): 5423-30, 2008 Sep 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-18683917
18.
Preclinical characterization of A-582941: a novel alpha7 neuronal nicotinic receptor agonist with broad spectrum cognition-enhancing properties.
CNS Neurosci Ther
; 14(1): 65-82, 2008.
Artigo
em Inglês
| MEDLINE | ID: mdl-18482100
19.
An orally active corticotropin releasing factor 1 receptor antagonist from 8-aryl-1,3a,7,8-tetraaza-cyclopenta[a]indenes.
Bioorg Med Chem Lett
; 17(7): 2026-30, 2007 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-17258456
20.
Synthesis, structure-activity relationships, and anxiolytic activity of 7-aryl-6,7-dihydroimidazoimidazole corticotropin-releasing factor 1 receptor antagonists.
Bioorg Med Chem Lett
; 15(17): 3870-3, 2005 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-15990298