Detalhe da pesquisa
1.
From structure to clinic: Design of a muscarinic M1 receptor agonist with potential to treatment of Alzheimer's disease.
Cell
; 184(24): 5886-5901.e22, 2021 11 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-34822784
2.
Oxygenation During Venoarterial Extracorporeal Membrane Oxygenation: Physiology, Current Evidence, and a Pragmatic Approach to Oxygen Titration.
Crit Care Med
; 52(4): 637-648, 2024 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38059745
3.
Frequency of and associations with alterations of medical emergency team calling criteria in a teaching hospital emergency department.
Aust Crit Care
; 37(2): 301-308, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-37716882
4.
Crystal structure of the GLP-1 receptor bound to a peptide agonist.
Nature
; 546(7657): 254-258, 2017 06 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-28562585
5.
Corrigendum: Crystal structure of the GLP-1 receptor bound to a peptide agonist.
Nature
; 548(7665): 122, 2017 08 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-28700581
6.
Extra-helical binding site of a glucagon receptor antagonist.
Nature
; 533(7602): 274-7, 2016 05 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-27111510
7.
Safety, pharmacokinetics and pharmacodynamics of HTL0009936, a selective muscarinic M1 -acetylcholine receptor agonist: A randomized cross-over trial.
Br J Clin Pharmacol
; 87(11): 4439-4449, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-33891333
8.
First-in-man study to investigate safety, pharmacokinetics and exploratory pharmacodynamics of HTL0018318, a novel M1 -receptor partial agonist for the treatment of dementias.
Br J Clin Pharmacol
; 87(7): 2945-2955, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-33351971
9.
Exploring the appropriateness of antibiotic prescribing for common respiratory tract infections in UK primary care.
J Antimicrob Chemother
; 75(1): 236-242, 2020 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31637421
10.
Identification of a novel allosteric GLP-1R antagonist HTL26119 using structure- based drug design.
Bioorg Med Chem Lett
; 29(20): 126611, 2019 10 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31447084
11.
Glucagon-Like Peptide-1 and Its Class B G Protein-Coupled Receptors: A Long March to Therapeutic Successes.
Pharmacol Rev
; 68(4): 954-1013, 2016 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-27630114
12.
The lack of anti-PF4 antibodies in convalescent plasma from COVID-19 infected blood donor.
Transfus Med
; 33(3): 272-273, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36994550
13.
Metabolic costs imposed by hydrostatic pressure constrain bathymetric range in the lithodid crab Lithodes maja.
J Exp Biol
; 220(Pt 21): 3916-3926, 2017 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29093188
14.
The Effects of Temperature and Hydrostatic Pressure on Metal Toxicity: Insights into Toxicity in the Deep Sea.
Environ Sci Technol
; 51(17): 10222-10231, 2017 Sep 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-28708382
15.
Hyperoxia during venoarterial ECMO: Culprit or co-variate? A comment from the BLENDER investigators.
Crit Care
; 26(1): 345, 2022 11 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-36348428
16.
A planetary health perspective on COVID-19: a call for papers.
Lancet
; 395(10230): 1099, 2020 04 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32247382
17.
Virtual consultations: Providing alternative ways of supporting patients with inherited bleeding disorders.
Haemophilia
; 27(4): e498-e501, 2021 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-33245838
18.
Recommendations of the 2006 Human Variome Project meeting.
Nat Genet
; 39(4): 433-6, 2007 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-17392799
19.
The role of ontogeny in physiological tolerance: decreasing hydrostatic pressure tolerance with development in the northern stone crab Lithodes maja.
Proc Biol Sci
; 282(1809): 20150577, 2015 06 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-26041343
20.
The effects of changing climate on faunal depth distributions determine winners and losers.
Glob Chang Biol
; 21(1): 173-80, 2015 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-25044552