Detalhe da pesquisa
1.
TDP-43 loss and ALS-risk SNPs drive mis-splicing and depletion of UNC13A.
Nature
; 603(7899): 131-137, 2022 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35197628
2.
RNA aptamer reveals nuclear TDP-43 pathology is an early aggregation event that coincides with STMN-2 cryptic splicing and precedes clinical manifestation in ALS.
Acta Neuropathol
; 147(1): 50, 2024 Mar 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-38443601
3.
Unexpected frequency of the pathogenic AR CAG repeat expansion in the general population.
Brain
; 146(7): 2723-2729, 2023 07 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36797998
4.
Correlates of Auditory Decision-Making in Prefrontal, Auditory, and Basal Lateral Amygdala Cortical Areas.
J Neurosci
; 41(6): 1301-1316, 2021 02 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-33303679
5.
FUS ALS-causative mutations impair FUS autoregulation and splicing factor networks through intron retention.
Nucleic Acids Res
; 48(12): 6889-6905, 2020 07 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32479602
6.
HnRNP K mislocalisation is a novel protein pathology of frontotemporal lobar degeneration and ageing and leads to cryptic splicing.
Acta Neuropathol
; 142(4): 609-627, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34274995
7.
Morphological variability is greater at developing than mature mouse neuromuscular junctions.
J Anat
; 237(4): 603-617, 2020 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32533580
8.
Finding driver mutations in cancer: Elucidating the role of background mutational processes.
PLoS Comput Biol
; 15(4): e1006981, 2019 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-31034466
9.
Blocking incidental frustration during bargaining.
Cogn Emot
; 33(2): 146-156, 2019 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29419354
10.
TDP-43 loss induces extensive cryptic polyadenylation in ALS/FTD.
bioRxiv
; 2024 Jan 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-38313254
11.
Mis-spliced transcripts generate de novo proteins in TDP-43-related ALS/FTD.
Sci Transl Med
; 16(734): eadg7162, 2024 02 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-38277467
12.
The era of cryptic exons: implications for ALS-FTD.
Mol Neurodegener
; 18(1): 16, 2023 03 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-36922834
13.
Creation of de novo cryptic splicing for ALS/FTD precision medicine.
bioRxiv
; 2023 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-38014203
14.
Mis-spliced transcripts generate de novo proteins in TDP-43-related ALS/FTD.
bioRxiv
; 2023 Jan 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-36747793
15.
NOS1AP is a novel molecular target and critical factor in TDP-43 pathology.
Brain Commun
; 4(5): fcac242, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36267332
16.
Cell environment shapes TDP-43 function with implications in neuronal and muscle disease.
Commun Biol
; 5(1): 314, 2022 04 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35383280
17.
Notch signaling and efficacy of PD-1/PD-L1 blockade in relapsed small cell lung cancer.
Nat Commun
; 12(1): 3880, 2021 06 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-34162872
18.
Clonal Evolution and Heterogeneity of Osimertinib Acquired Resistance Mechanisms in EGFR Mutant Lung Cancer.
Cell Rep Med
; 1(1)2020 04 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-32483558
19.
Truncated stathmin-2 is a marker of TDP-43 pathology in frontotemporal dementia.
J Clin Invest
; 130(11): 6080-6092, 2020 11 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-32790644
20.
APOBEC Mutagenesis and Copy-Number Alterations Are Drivers of Proteogenomic Tumor Evolution and Heterogeneity in Metastatic Thoracic Tumors.
Cell Rep
; 26(10): 2651-2666.e6, 2019 03 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30840888