Detalhe da pesquisa
1.
Survey of pharmaceutical industry's best practices around in vitro transporter assessment and Implications for Drug Development: Considerations from the IQ Transporter Working Group.
Drug Metab Dispos
; 2024 May 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-38697852
2.
Assessment of Skin Toxicity in an in Vitro Reconstituted Human Epidermis Model Using Deep Learning.
Am J Pathol
; 192(4): 687-700, 2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35063406
3.
In vitro assessment of farnesoid X receptor antagonism to predict drug-induced liver injury risk.
Arch Toxicol
; 94(9): 3185-3200, 2020 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32583097
4.
An Automated Image Analysis Method to Quantify Veterinary Bone Marrow Cellularity on H&E Sections.
Toxicol Pathol
; 46(3): 324-335, 2018 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-29683091
5.
Effect of varying degrees of renal impairment on the pharmacokinetics and tolerability of taspoglutide.
Diabetes Obes Metab
; 19(4): 537-544, 2017 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-27981717
6.
Effects of dalcetrapib in patients with a recent acute coronary syndrome.
N Engl J Med
; 367(22): 2089-99, 2012 Nov 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-23126252
7.
Analysis of cellularity in H&E-stained rat bone marrow tissue via deep learning.
J Pathol Inform
; 14: 100333, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37743975
8.
Introducing dendritic cell antibody internalization as an immunogenicity risk assessment tool.
Bioanalysis
; 14(10): 703-713, 2022 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-35593734
9.
Immunogenicity risk assessment for biotherapeutics through in vitro detection of CD134 and CD137 on T helper cells.
MAbs
; 13(1): 1898831, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33729092
10.
An integrated approach for characterizing immunogenic responses toward a bispecific antibody.
MAbs
; 13(1): 1944017, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34225571
11.
A Comprehensive Analysis of the Stability of Blood Eosinophil Levels.
Ann Am Thorac Soc
; 18(12): 1978-1987, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33891831
12.
Assessment of Drug-Drug Interactions between Taspoglutide, a Glucagon-Like Peptide-1 Agonist, and Drugs Commonly Used in Type 2 Diabetes Mellitus: Results of Five Phase I Trials.
Clin Pharmacokinet
; 58(9): 1205-1214, 2019 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-30968335
13.
Establishment of neurofilament light chain Simoa assay in cerebrospinal fluid and blood.
Bioanalysis
; 11(15): 1405-1418, 2019 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-31401845
14.
Phase I study of the anti-FcRH5 antibody-drug conjugate DFRF4539A in relapsed or refractory multiple myeloma.
Blood Cancer J
; 9(2): 17, 2019 02 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30718503
15.
Single cell-produced and in vitro-assembled anti-FcRH5/CD3 T-cell dependent bispecific antibodies have similar in vitro and in vivo properties.
MAbs
; 11(2): 422-433, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-30550367
16.
2019 White Paper on Recent Issues in Bioanalysis: FDA Immunogenicity Guidance, Gene Therapy, Critical Reagents, Biomarkers and Flow Cytometry Validation (Part 3 - Recommendations on 2019 FDA Immunogenicity Guidance, Gene Therapy Bioanalytical Challenges, Strategies for Critical Reagent Management, Biomarker Assay Validation, Flow Cytometry Validation & CLSI H62).
Bioanalysis
; 11(24): 2207-2244, 2019 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-31820675
17.
oPOSSUM: identification of over-represented transcription factor binding sites in co-expressed genes.
Nucleic Acids Res
; 33(10): 3154-64, 2005.
Artigo
em Inglês
| MEDLINE | ID: mdl-15933209
18.
Interleukin-13 in Asthma and Other Eosinophilic Disorders.
Front Med (Lausanne)
; 4: 139, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-29034234
19.
Evaluation of in-study cut points to enable appropriate interpretation of clinical immunogenicity results.
Bioanalysis
; 11(17): 1539-1541, 2019 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-31208203
20.
Discovery and expansion of gene modules by seeking isolated groups in a random graph process.
PLoS One
; 3(10): e3358, 2008.
Artigo
em Inglês
| MEDLINE | ID: mdl-18843375