Detalhe da pesquisa
1.
Synthesis of the Marine Alkaloid Cylindricine C and Serendipitous Synthesis of Its 2,13-Di-epi Stereoisomer.
J Org Chem
; 88(19): 13813-13824, 2023 Oct 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37722076
2.
NBI-921352, a first-in-class, NaV1.6 selective, sodium channel inhibitor that prevents seizures in Scn8a gain-of-function mice, and wild-type mice and rats.
Elife
; 112022 03 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-35234610
3.
Identification of CNS-Penetrant Aryl Sulfonamides as Isoform-Selective NaV1.6 Inhibitors with Efficacy in Mouse Models of Epilepsy.
J Med Chem
; 62(21): 9618-9641, 2019 11 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-31525968
4.
Discovery of a Novel Small-Molecule Modulator of C-X-C Chemokine Receptor Type 7 as a Treatment for Cardiac Fibrosis.
J Med Chem
; 61(8): 3685-3696, 2018 04 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-29627981
5.
The effect of host structure on the selectivity and mechanism of supramolecular catalysis of Prins cyclizations.
Chem Sci
; 6(2): 1383-1393, 2015 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29560226
6.
Expedient synthesis of α-(2-azaheteroaryl) acetates via the addition of silyl ketene acetals to azine-N-oxides.
Org Lett
; 16(12): 3336-9, 2014 Jun 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-24885646