Assuntos
Anemia Hemolítica Autoimune/complicações , Infecções por Coronavirus/complicações , Pneumonia Viral/complicações , Trombocitopenia/complicações , Corticosteroides , Adulto , Anemia Hemolítica Autoimune/terapia , Betacoronavirus , COVID-19 , Infecções por Coronavirus/terapia , Hemorragia/terapia , Humanos , Imunoglobulinas Intravenosas/uso terapêutico , Terapia de Imunossupressão , Masculino , Pandemias , Pneumonia Viral/terapia , SARS-CoV-2 , Trombocitopenia/terapiaRESUMO
We present a case of a 58-year-old male patient who presented to his primary care clinic with complaints of eye swelling and fatigue. Workup ultimately led to a diagnosis of AL amyloidosis secondary to myeloma based on SLiM-CRAB criteria. We discuss his diagnostic workup, treatment, and subsequent relapse.
RESUMO
Older women experience a large share of breast cancer incidence and death. With the projected rise in the number of older cancer patients, adjuvant chemo-, radiation and endocrine therapy management will become a key component of breast cancer treatment in older women. Many factors influence adjuvant treatment decisions including patient preferences, life expectancy and tumor biology. Geriatric assessment predicts important outcomes, identifies key deficits, and can aid in the decision making process. This review utilizes clinical vignettes to illustrate core principles in adjuvant management of breast cancer in older women and suggests an approach incorporating life expectancy and geriatric assessment.