Detalhe da pesquisa
1.
Cell-type- and region-specific modulation of cocaine seeking by micro-RNA-1 in striatal projection neurons.
Mol Psychiatry
; 27(2): 918-928, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34785784
2.
Npas4 regulates medium spiny neuron physiology and gates cocaine-induced hyperlocomotion.
EMBO Rep
; 22(12): e51882, 2021 12 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-34661342
3.
Cell-Type Specific Regulation of Cholesterogenesis by CYP46A1 Re-Expression in zQ175 HD Mouse Striatum.
Int J Mol Sci
; 24(13)2023 Jul 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-37446179
4.
Early epigenomic and transcriptional changes reveal Elk-1 transcription factor as a therapeutic target in Huntington's disease.
Proc Natl Acad Sci U S A
; 116(49): 24840-24851, 2019 12 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31744868
5.
CYP46A1 gene therapy deciphers the role of brain cholesterol metabolism in Huntington's disease.
Brain
; 142(8): 2432-2450, 2019 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31286142
6.
Cocaine conditioned place preference: unexpected suppression of preference due to testing combined with strong conditioning.
Addict Biol
; 24(3): 364-375, 2019 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29318708
7.
Coupling of D2R Short but not D2R Long receptor isoform to the Rho/ROCK signaling pathway renders striatal neurons vulnerable to mutant huntingtin.
Eur J Neurosci
; 45(1): 198-206, 2017 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27717053
8.
CYP46A1, the rate-limiting enzyme for cholesterol degradation, is neuroprotective in Huntington's disease.
Brain
; 139(Pt 3): 953-70, 2016 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-26912634
9.
Dopamine signaling leads to loss of Polycomb repression and aberrant gene activation in experimental parkinsonism.
PLoS Genet
; 10(9): e1004574, 2014 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-25254549
10.
Mitogen- and stress-activated protein kinase 1-induced neuroprotection in Huntington's disease: role on chromatin remodeling at the PGC-1-alpha promoter.
Hum Mol Genet
; 20(12): 2422-34, 2011 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21493629
11.
Alterations of molecular and behavioral responses to cocaine by selective inhibition of Elk-1 phosphorylation.
J Neurosci
; 31(40): 14296-307, 2011 Oct 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-21976515
12.
Altered Cholesterol Homeostasis in Huntington's Disease.
Front Aging Neurosci
; 14: 797220, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35517051
13.
A positive allosteric modulator of mGlu4 receptors restores striatal plasticity in an animal model of l-Dopa-induced dyskinesia.
Neuropharmacology
; 218: 109205, 2022 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35940348
14.
Disrupting D1-NMDA or D2-NMDA receptor heteromerization prevents cocaine's rewarding effects but preserves natural reward processing.
Sci Adv
; 7(43): eabg5970, 2021 Oct 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-34669474
15.
Endocytosis controls glutamate-induced nuclear accumulation of ERK.
Mol Cell Neurosci
; 41(3): 325-36, 2009 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-19398002
16.
Huntington's disease.
Adv Exp Med Biol
; 685: 45-63, 2010.
Artigo
em Inglês
| MEDLINE | ID: mdl-20687494
17.
From Signaling Molecules to Circuits and Behaviors: Cell-Type-Specific Adaptations to Psychostimulant Exposure in the Striatum.
Biol Psychiatry
; 87(11): 944-953, 2020 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31928716
18.
The cholesterol 24-hydroxylase activates autophagy and decreases mutant huntingtin build-up in a neuroblastoma culture model of Huntington's disease.
BMC Res Notes
; 13(1): 210, 2020 Apr 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32276655
19.
Role of the ERK/MSK1 signalling pathway in chromatin remodelling and brain responses to drugs of abuse.
J Neurochem
; 108(6): 1323-35, 2009 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-19183268
20.
Mitogen- and stress-activated protein kinase-1 deficiency is involved in expanded-huntingtin-induced transcriptional dysregulation and striatal death.
FASEB J
; 22(4): 1083-93, 2008 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-18029446