Detalhe da pesquisa
1.
Profiling interactions of vaborbactam with metallo-ß-lactamases.
Bioorg Med Chem Lett
; 29(15): 1981-1984, 2019 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31171422
2.
Structural/mechanistic insights into the efficacy of nonclassical ß-lactamase inhibitors against extensively drug resistant Stenotrophomonas maltophilia clinical isolates.
Mol Microbiol
; 106(3): 492-504, 2017 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-28876489
3.
Cyclic Boronates Inhibit All Classes of ß-Lactamases.
Antimicrob Agents Chemother
; 61(4)2017 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-28115348
4.
Applications of structure-based design to antibacterial drug discovery.
Bioorg Chem
; 55: 69-76, 2014 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-24962384
5.
Discovery of Novel UDP-N-Acetylglucosamine Acyltransferase (LpxA) Inhibitors with Activity against Pseudomonas aeruginosa.
J Med Chem
; 64(19): 14377-14425, 2021 10 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-34569791
6.
Anti-biofilm efficacy of a medieval treatment for bacterial infection requires the combination of multiple ingredients.
Sci Rep
; 10(1): 12687, 2020 07 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-32724094
7.
Bicyclic Boronates as Potent Inhibitors of AmpC, the Class C ß-Lactamase from Escherichia coli.
Biomolecules
; 10(6)2020 06 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-32545682
8.
Structure-Guided Enhancement of Selectivity of Chemical Probe Inhibitors Targeting Bacterial Seryl-tRNA Synthetase.
J Med Chem
; 62(21): 9703-9717, 2019 11 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-31626547
9.
Studies on the inhibition of AmpC and other ß-lactamases by cyclic boronates.
Biochim Biophys Acta Gen Subj
; 1863(4): 742-748, 2019 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30738906
10.
In Silico Fragment-Based Design Identifies Subfamily B1 Metallo-ß-lactamase Inhibitors.
J Med Chem
; 61(3): 1255-1260, 2018 02 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29271657
11.
A chemical genomics approach to drug reprofiling in oncology: Antipsychotic drug risperidone as a potential adenocarcinoma treatment.
Cancer Lett
; 393: 16-21, 2017 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28188816
12.
Structural basis of metallo-ß-lactamase, serine-ß-lactamase and penicillin-binding protein inhibition by cyclic boronates.
Nat Commun
; 7: 12406, 2016 08 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-27499424
13.
Computational methods to identify new antibacterial targets.
Chem Biol Drug Des
; 85(1): 22-9, 2015 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-24974974
14.
Anabolic and catabolic bone effects of human parathyroid hormone (1-34) are predicted by duration of hormone exposure.
Bone
; 33(3): 372-9, 2003 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-13678779
15.
Assay platform for clinically relevant metallo-ß-lactamases.
J Med Chem
; 56(17): 6945-53, 2013 Sep 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-23898798
16.
Novel and selective small molecule stimulators of osteoprotegerin expression inhibit bone resorption.
J Pharmacol Exp Ther
; 309(1): 369-79, 2004 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-14718597