Detalhe da pesquisa
1.
A dimer-monomer switch controls CHIP-dependent substrate ubiquitylation and processing.
Mol Cell
; 82(17): 3239-3254.e11, 2022 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36027913
2.
A heterotypic assembly mechanism regulates CHIP E3 ligase activity.
EMBO J
; 41(15): e109566, 2022 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35762422
3.
A peptidomimetic modulator of the CaV2.2 N-type calcium channel for chronic pain.
Proc Natl Acad Sci U S A
; 120(47): e2305215120, 2023 Nov 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-37972067
4.
Author Correction: A heterotypic assembly mechanism regulates CHIP E3 ligase activity.
EMBO J
; 43(6): 1110-1111, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38388749
5.
Defining the Kv2.1-syntaxin molecular interaction identifies a first-in-class small molecule neuroprotectant.
Proc Natl Acad Sci U S A
; 116(31): 15696-15705, 2019 07 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-31308225
6.
Electrophilic fatty acids impair RAD51 function and potentiate the effects of DNA-damaging agents on growth of triple-negative breast cells.
J Biol Chem
; 294(2): 397-404, 2019 01 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30478172
7.
A combined computational and experimental approach reveals the structure of a C/EBPß-Spi1 interaction required for IL1B gene transcription.
J Biol Chem
; 293(52): 19942-19956, 2018 12 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-30355733
8.
Predicting protein targets for drug-like compounds using transcriptomics.
PLoS Comput Biol
; 14(12): e1006651, 2018 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30532261
9.
Optimal affinity ranking for automated virtual screening validated in prospective D3R grand challenges.
J Comput Aided Mol Des
; 32(1): 287-297, 2018 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28918599
10.
Extensive Citrullination Promotes Immunogenicity of HSP90 through Protein Unfolding and Exposure of Cryptic Epitopes.
J Immunol
; 197(5): 1926-36, 2016 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27448590
11.
Peroxidase activation of cytoglobin by anionic phospholipids: Mechanisms and consequences.
Biochim Biophys Acta
; 1861(5): 391-401, 2016 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-26928591
12.
Structure Guided Chemical Modifications of Propylthiouracil Reveal Novel Small Molecule Inhibitors of Cytochrome b5 Reductase 3 That Increase Nitric Oxide Bioavailability.
J Biol Chem
; 290(27): 16861-72, 2015 Jul 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-26001785
13.
Restricted protein phosphatase 2A targeting by Merkel cell polyomavirus small T antigen.
J Virol
; 89(8): 4191-200, 2015 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-25631078
14.
Choosing the Optimal Rigid Receptor for Docking and Scoring in the CSAR 2013/2014 Experiment.
J Chem Inf Model
; 56(6): 1004-12, 2016 06 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-26222931
15.
Optimal strategies for virtual screening of induced-fit and flexible target in the 2015 D3R Grand Challenge.
J Comput Aided Mol Des
; 30(9): 695-706, 2016 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-27573981
16.
Indexing Volumetric Shapes with Matching and Packing.
Knowl Inf Syst
; 43(1): 157-180, 2015 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26085707
17.
Discovery of a Potent Allosteric Kinase Modulator by Combining Computational and Synthetic Methods.
Angew Chem Int Ed Engl
; 54(47): 13933-6, 2015 Nov 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-26385475
18.
Shape-based virtual screening with volumetric aligned molecular shapes.
J Comput Chem
; 35(25): 1824-34, 2014 Sep 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-25049193
19.
PocketQuery: protein-protein interaction inhibitor starting points from protein-protein interaction structure.
Nucleic Acids Res
; 40(Web Server issue): W387-92, 2012 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-22523085
20.
ZINCPharmer: pharmacophore search of the ZINC database.
Nucleic Acids Res
; 40(Web Server issue): W409-14, 2012 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-22553363