Detalhe da pesquisa
1.
A global in vivo Drosophila RNAi screen identifies NOT3 as a conserved regulator of heart function.
Cell
; 141(1): 142-53, 2010 Apr 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-20371351
2.
TNNT2 mutations in the tropomyosin binding region of TNT1 disrupt its role in contractile inhibition and stimulate cardiac dysfunction.
Proc Natl Acad Sci U S A
; 117(31): 18822-18831, 2020 08 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32690703
3.
Myofibril orientation as a metric for characterizing heart disease.
Biophys J
; 121(4): 565-574, 2022 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35032456
4.
The R369 Myosin Residue within Loop 4 Is Critical for Actin Binding and Muscle Function in Drosophila.
Int J Mol Sci
; 23(5)2022 Feb 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-35269675
5.
Lysine acetylation of F-actin decreases tropomyosin-based inhibition of actomyosin activity.
J Biol Chem
; 295(46): 15527-15539, 2020 11 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-32873710
6.
Site-specific acetyl-mimetic modification of cardiac troponin I modulates myofilament relaxation and calcium sensitivity.
J Mol Cell Cardiol
; 139: 135-147, 2020 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31981571
7.
The actin 'A-triad's' role in contractile regulation in health and disease.
J Physiol
; 598(14): 2897-2908, 2020 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-30770548
8.
Myosin storage myopathy mutations yield defective myosin filament assembly in vitro and disrupted myofibrillar structure and function in vivo.
Hum Mol Genet
; 26(24): 4799-4813, 2017 12 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28973424
9.
Fropofol decreases force development in cardiac muscle.
FASEB J
; 32(8): 4203-4213, 2018 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29522375
10.
Conservation of cardiac L-type Ca2+ channels and their regulation in Drosophila: A novel genetically-pliable channelopathic model.
J Mol Cell Cardiol
; 119: 64-74, 2018 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29684406
11.
A Drosophila melanogaster model of diastolic dysfunction and cardiomyopathy based on impaired troponin-T function.
Circ Res
; 114(2): e6-17, 2014 Jan 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-24221941
12.
The NADPH metabolic network regulates human αB-crystallin cardiomyopathy and reductive stress in Drosophila melanogaster.
PLoS Genet
; 9(6): e1003544, 2013 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-23818860
13.
Measuring passive myocardial stiffness in Drosophila melanogaster to investigate diastolic dysfunction.
J Cell Mol Med
; 16(8): 1656-62, 2012 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-22225769
14.
Myosin Transducer Inter-Strand Communication Is Critical for Normal ATPase Activity and Myofibril Structure.
Biology (Basel)
; 11(8)2022 Jul 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-36009764
15.
In situ mechanical analysis of myofibrillar perturbation and aging on soft, bilayered Drosophila myocardium.
Biophys J
; 101(11): 2629-37, 2011 Dec 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-22261050
16.
Cardiomyopathic troponin mutations predominantly occur at its interface with actin and tropomyosin.
J Gen Physiol
; 153(3)2021 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33492345
17.
Acoustotactic response of mosquitoes in untethered flight to incidental sound.
Sci Rep
; 11(1): 1884, 2021 01 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-33479423
18.
Myosin dilated cardiomyopathy mutation S532P disrupts actomyosin interactions, leading to altered muscle kinetics, reduced locomotion, and cardiac dilation in Drosophila.
Mol Biol Cell
; 32(18): 1690-1706, 2021 08 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-34081531
19.
CaMKII oxidation is a critical performance/disease trade-off acquired at the dawn of vertebrate evolution.
Nat Commun
; 12(1): 3175, 2021 05 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-34039988
20.
Electron microscopy and persistence length analysis of semi-rigid smooth muscle tropomyosin strands.
Biophys J
; 99(3): 862-8, 2010 Aug 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-20682264