Detalhe da pesquisa
1.
Small molecule inhibits α-synuclein aggregation, disrupts amyloid fibrils, and prevents degeneration of dopaminergic neurons.
Proc Natl Acad Sci U S A
; 115(41): 10481-10486, 2018 10 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-30249646
2.
Environmental and genetic factors support the dissociation between α-synuclein aggregation and toxicity.
Proc Natl Acad Sci U S A
; 113(42): E6506-E6515, 2016 10 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-27708160
3.
Computational Assessment of Bacterial Protein Structures Indicates a Selection Against Aggregation.
Cells
; 8(8)2019 08 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31398930
4.
ZPD-2, a Small Compound That Inhibits α-Synuclein Amyloid Aggregation and Its Seeded Polymerization.
Front Mol Neurosci
; 12: 306, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31920537
5.
Biasing the native α-synuclein conformational ensemble towards compact states abolishes aggregation and neurotoxicity.
Redox Biol
; 22: 101135, 2019 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30769283
6.
Evaluation of the Impact of Protein Aggregation on Cellular Oxidative Stress in Yeast.
J Vis Exp
; (136)2018 06 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-29985335
7.
Protein aggregation into insoluble deposits protects from oxidative stress.
Redox Biol
; 12: 699-711, 2017 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-28410533
8.
Data on correlation between Aß42 structural aggregation propensity and toxicity in bacteria.
Data Brief
; 7: 143-7, 2016 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-27408907
9.
A fast and specific method to screen for intracellular amyloid inhibitors using bacterial model systems.
Eur J Med Chem
; 121: 785-792, 2016 Oct 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-26608003
10.
The effects of the novel A53E alpha-synuclein mutation on its oligomerization and aggregation.
Acta Neuropathol Commun
; 4(1): 128, 2016 12 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-27938414