Detalhe da pesquisa
1.
IL-1 induces mitochondrial translocation of IRAK2 to suppress oxidative metabolism in adipocytes.
Nat Immunol
; 21(10): 1219-1231, 2020 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32778760
2.
The psoriasis-associated D10N variant of the adaptor Act1 with impaired regulation by the molecular chaperone hsp90.
Nat Immunol
; 14(1): 72-81, 2013 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-23202271
3.
Selective IRAK4 Inhibition Attenuates Disease in Murine Lupus Models and Demonstrates Steroid Sparing Activity.
J Immunol
; 198(3): 1308-1319, 2017 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28003376
4.
HuR is required for IL-17-induced Act1-mediated CXCL1 and CXCL5 mRNA stabilization.
J Immunol
; 191(2): 640-9, 2013 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23772036
5.
Cytotoxic CD8+ T cells target citrullinated antigens in rheumatoid arthritis.
Nat Commun
; 14(1): 319, 2023 01 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-36658110
6.
Optimization of Nicotinamides as Potent and Selective IRAK4 Inhibitors with Efficacy in a Murine Model of Psoriasis.
ACS Med Chem Lett
; 11(7): 1402-1409, 2020 Jul 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32676146
7.
Abatacept does not induce direct gene expression changes in antigen-presenting cells.
J Clin Immunol
; 29(4): 479-89, 2009 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-19259798
8.
Autoimmune pathways in mice and humans are blocked by pharmacological stabilization of the TYK2 pseudokinase domain.
Sci Transl Med
; 11(502)2019 07 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-31341059
9.
Development of a Molecular Signature to Monitor Pharmacodynamic Responses Mediated by In Vivo Administration of Glucocorticoids.
Arthritis Rheumatol
; 70(8): 1331-1342, 2018 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29534336
10.
Circulating T Cell Subpopulations Correlate With Immune Responses at the Tumor Site and Clinical Response to PD1 Inhibition in Non-Small Cell Lung Cancer.
Front Immunol
; 9: 1613, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-30123214
11.
IL-17 induced NOTCH1 activation in oligodendrocyte progenitor cells enhances proliferation and inflammatory gene expression.
Nat Commun
; 8: 15508, 2017 05 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-28561022
12.
IRAK2 directs stimulus-dependent nuclear export of inflammatory mRNAs.
Elife
; 62017 10 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-28990926
13.
Direct association of tristetraprolin with the nucleoporin CAN/Nup214.
Biochem Biophys Res Commun
; 315(2): 445-9, 2004 Mar 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-14766228