Detalhe da pesquisa
1.
Optimization of medium with perfusion microbioreactors for high density CHO cell cultures at very low renewal rate aided by design of experiments.
Biotechnol Bioeng
; 120(9): 2523-2541, 2023 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37079436
2.
Integrated continuous biomanufacturing on pilot scale for acid-sensitive monoclonal antibodies.
Biotechnol Bioeng
; 119(8): 2152-2166, 2022 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35470430
3.
Control of IgG glycosylation in CHO cell perfusion cultures by GReBA mathematical model supported by a novel targeted feed, TAFE.
Metab Eng
; 65: 135-145, 2021 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33161144
4.
Probabilistic model by Bayesian network for the prediction of antibody glycosylation in perfusion and fed-batch cell cultures.
Biotechnol Bioeng
; 118(9): 3447-3459, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-33788254
5.
Glycan Residues Balance Analysis - GReBA: A novel model for the N-linked glycosylation of IgG produced by CHO cells.
Metab Eng
; 57: 118-128, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31539564
6.
Hydrocyclones as cell retention device for CHO perfusion processes in single-use bioreactors.
Biotechnol Bioeng
; 117(7): 1915-1928, 2020 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32181883
7.
Rapid development of clone-specific, high-performing perfusion media from established feed supplements.
Biotechnol Prog
; 36(2): e2933, 2020 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31680446
8.
Model-based design and control of a small-scale integrated continuous end-to-end mAb platform.
Biotechnol Prog
; 36(4): e2995, 2020 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32233078
9.
Combined effects of glycosylation precursors and lactate on the glycoprofile of IgG produced by CHO cells.
J Biotechnol
; 289: 71-79, 2019 Jan 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-30423367
10.
Repurposing fed-batch media and feeds for highly productive CHO perfusion processes.
Biotechnol Prog
; 35(4): e2821, 2019 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-30985083
11.
Bioprocessing of Recombinant CHO-K1, CHO-DG44, and CHO-S: CHO Expression Hosts Favor Either mAb Production or Biomass Synthesis.
Biotechnol J
; 14(3): e1700686, 2019 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-29701329
12.
Label-free independent quantitation of viable and non-viable cells using a multivariable multi-resonant sensor.
Bioelectrochemistry
; 125: 97-104, 2019 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-30342232
13.
Differential gene expression of a feed-spiked super-producing CHO cell line.
J Biotechnol
; 285: 23-37, 2018 Nov 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-30157452
14.
Biphasic cultivation strategy to avoid Epo-Fc aggregation and optimize protein expression.
J Biotechnol
; 227: 3-9, 2016 Jun 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-27050504
15.
Influence of bioreactor scale and complex medium on probing control of glucose feeding in cultivations of recombinant strains of Escherichia coli.
Biotechnol Bioeng
; 97(4): 816-24, 2007 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-17163511
16.
Formate accumulation due to DNA release in aerobic cultivations of Escherichia coli.
Biotechnol Bioeng
; 77(3): 324-8, 2002 Feb 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-11753941