Detalhe da pesquisa
1.
Redox Properties of Bacillus subtilis Ferredoxin:NADP+ Oxidoreductase: Potentiometric Characteristics and Reactions with Pro-Oxidant Xenobiotics.
Int J Mol Sci
; 25(10)2024 May 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-38791410
2.
The Catalysis Mechanism of E. coli Nitroreductase A, a Candidate for Gene-Directed Prodrug Therapy: Potentiometric and Substrate Specificity Studies.
Int J Mol Sci
; 25(8)2024 Apr 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-38673999
3.
Enzymatic Redox Properties and Cytotoxicity of Irreversible Nitroaromatic Thioredoxin Reductase Inhibitors in Mammalian Cells.
Int J Mol Sci
; 24(15)2023 Aug 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37569833
4.
Redox Proteomic Profile of Tirapazamine-Resistant Murine Hepatoma Cells.
Int J Mol Sci
; 24(7)2023 Apr 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37047836
5.
The Crystal Structure of Engineered Nitroreductase NTR 2.0 and Impact of F70A and F108Y Substitutions on Substrate Specificity.
Int J Mol Sci
; 24(7)2023 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37047605
6.
Reactions of Recombinant Neuronal Nitric Oxide Synthase with Redox Cycling Xenobiotics: A Mechanistic Study.
Int J Mol Sci
; 23(2)2022 Jan 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-35055166
7.
Single- and Two-Electron Reduction of Nitroaromatic Compounds by Flavoenzymes: Mechanisms and Implications for Cytotoxicity.
Int J Mol Sci
; 22(16)2021 Aug 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34445240
8.
Reactions of Plasmodium falciparum Ferredoxin:NADP+ Oxidoreductase with Redox Cycling Xenobiotics: A Mechanistic Study.
Int J Mol Sci
; 21(9)2020 May 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-32370303
9.
Aerobic Cytotoxicity of Aromatic N-Oxides: The Role of NAD(P)H:Quinone Oxidoreductase (NQO1).
Int J Mol Sci
; 21(22)2020 Nov 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-33228195
10.
Kinetics of Flavoenzyme-Catalyzed Reduction of Tirapazamine Derivatives: Implications for Their Prooxidant Cytotoxicity.
Int J Mol Sci
; 20(18)2019 Sep 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-31533349
11.
Antiplasmodial Activity of Nitroaromatic Compounds: Correlation with Their Reduction Potential and Inhibitory Action on Plasmodium falciparum Glutathione Reductase.
Molecules
; 24(24)2019 Dec 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31835450
12.
Mechanism of Two-/Four-Electron Reduction of Nitroaromatics by Oxygen-Insensitive Nitroreductases: The Role of a Non-Enzymatic Reduction Step.
Molecules
; 23(7)2018 Jul 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-29987261
13.
Quantitative proteomic analysis of anticancer drug RH1 resistance in liver carcinoma.
Biochim Biophys Acta
; 1864(2): 219-32, 2016 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-26596252
14.
Reduction of quinones and nitroaromatic compounds by Escherichia coli nitroreductase A (NfsA): Characterization of kinetics and substrate specificity.
Arch Biochem Biophys
; 614: 14-22, 2017 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27986535
15.
Study of Bioreductive Anticancer Agent RH-1-Induced Signals Leading the Wild-Type p53-Bearing Lung Cancer A549 Cells to Apoptosis.
Chem Res Toxicol
; 29(1): 26-39, 2016 Jan 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-26630137
16.
Naphtho[1',2':4,5]imidazo[1,2-a]pyridine-5,6-diones: Synthesis, enzymatic reduction and cytotoxic activity.
Bioorg Med Chem Lett
; 26(2): 512-517, 2016 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26681508
17.
The study of NADPH-dependent flavoenzyme-catalyzed reduction of benzo[1,2-c]1,2,5-oxadiazole N-oxides (benzofuroxans).
Int J Mol Sci
; 15(12): 23307-31, 2014 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25517035
18.
Modified quantum mechanical approach for the estimation of single-electron reduction potential of nitroaromatic compounds in aqueous medium.
Free Radic Res
; 57(3): 153-160, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-37171206
19.
Quinone- and nitroreductase reactions of Thermotoga maritima peroxiredoxin-nitroreductase hybrid enzyme.
Arch Biochem Biophys
; 528(1): 50-6, 2012 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22982531
20.
Thioredoxin Reductase-Type Ferredoxin: NADP+ Oxidoreductase of Rhodopseudomonas palustris: Potentiometric Characteristics and Reactions with Nonphysiological Oxidants.
Antioxidants (Basel)
; 11(5)2022 May 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-35624864