Detalhe da pesquisa
1.
Omics analyses of a somatic Trp53R245W/+ breast cancer model identify cooperating driver events activating PI3K/AKT/mTOR signaling.
Proc Natl Acad Sci U S A
; 119(45): e2210618119, 2022 Nov 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-36322759
2.
FZR1 loss increases sensitivity to DNA damage and consequently promotes murine and human B-cell acute leukemia.
Blood
; 129(14): 1958-1968, 2017 04 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-28143883
3.
Preclinical activity of the novel B-cell-specific Moloney murine leukemia virus integration site 1 inhibitor PTC-209 in acute myeloid leukemia: Implications for leukemia therapy.
Cancer Sci
; 106(12): 1705-13, 2015 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-26450753
4.
Unique Transcriptional Profiles Underlie Osteosarcomagenesis Driven by Different p53 Mutants.
Cancer Res
; 83(14): 2297-2311, 2023 07 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-37205631
5.
In silico analysis of DND1 and its co-expressed genes in human cancers.
Biochem Biophys Rep
; 29: 101206, 2022 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-35059511
6.
Differential Gain-of-Function Activity of Three p53 Hotspot Mutants In Vivo.
Cancer Res
; 82(10): 1926-1936, 2022 05 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-35320355
7.
Inhibition of translation initiation factor eIF4a inactivates heat shock factor 1 (HSF1) and exerts anti-leukemia activity in AML.
Leukemia
; 35(9): 2469-2481, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34127794
8.
Predictive Gene Signatures Determine Tumor Sensitivity to MDM2 Inhibition.
Cancer Res
; 78(10): 2721-2731, 2018 05 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29490944
9.
ATF4 induction through an atypical integrated stress response to ONC201 triggers p53-independent apoptosis in hematological malignancies.
Sci Signal
; 9(415): ra17, 2016 Feb 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-26884599
10.
Mitochondrial Profiling of Acute Myeloid Leukemia in the Assessment of Response to Apoptosis Modulating Drugs.
PLoS One
; 10(9): e0138377, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-26375587