Detalhe da pesquisa
1.
Potent and selective inhibitors of PI3Kδ: obtaining isoform selectivity from the affinity pocket and tryptophan shelf.
Bioorg Med Chem Lett
; 22(13): 4296-302, 2012 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22672799
2.
A crucial role for the p110delta subunit of phosphatidylinositol 3-kinase in B cell development and activation.
J Exp Med
; 196(6): 753-63, 2002 Sep 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-12235209
3.
Targeting of colony-stimulating factor 1 receptor (CSF1R) in the CLL microenvironment yields antineoplastic activity in primary patient samples.
Oncotarget
; 9(37): 24576-24589, 2018 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29872489
4.
CCR4-bearing T cells participate in autoimmune diabetes.
J Clin Invest
; 110(11): 1675-86, 2002 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-12464673
5.
Pexmetinib: A Novel Dual Inhibitor of Tie2 and p38 MAPK with Efficacy in Preclinical Models of Myelodysplastic Syndromes and Acute Myeloid Leukemia.
Cancer Res
; 76(16): 4841-4849, 2016 08 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27287719
6.
Inflammation Research Association: 12th international conference.
Expert Opin Emerg Drugs
; 10(1): 219-24, 2005 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-15757413
7.
Chemokines in allergy.
Curr Drug Targets Inflamm Allergy
; 1(1): 109-16, 2002 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-14561210
8.
HIV entry and fusion inhibitors.
Expert Opin Emerg Drugs
; 9(1): 1-7, 2004 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-15155132
9.
Potent and highly selective benzimidazole inhibitors of PI3-kinase delta.
J Med Chem
; 55(17): 7686-95, 2012 Sep 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-22877085
10.
G protein-coupled receptors: from ligand identification to drug targets. 14-16 October 2002, San Diego, CA, USA.
Expert Opin Emerg Drugs
; 8(1): 273-6, 2003 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-14610927
11.
Discovery and SAR of trisubstituted thiazolidinones as CCR4 antagonists.
Bioorg Med Chem Lett
; 14(7): 1619-24, 2004 Apr 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-15026036
12.
Racemic and chiral lactams as potent, selective and functionally active CCR4 antagonists.
Bioorg Med Chem Lett
; 14(22): 5537-42, 2004 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-15482919
13.
Presence of high contents of thymus and activation-regulated chemokine in platelets and elevated plasma levels of thymus and activation-regulated chemokine and macrophage-derived chemokine in patients with atopic dermatitis.
J Allergy Clin Immunol
; 110(1): 139-46, 2002 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-12110833
14.
IFN-gamma-inducible expression of thymus and activation-regulated chemokine/CCL17 and macrophage-derived chemokine/CCL22 in epidermal keratinocytes and their roles in atopic dermatitis.
Int Immunol
; 14(7): 767-73, 2002 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-12096036