Detalhe da pesquisa
1.
Structural insight into allosteric modulation of protease-activated receptor 2.
Nature
; 545(7652): 112-115, 2017 05 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-28445455
2.
Structure of class B GPCR corticotropin-releasing factor receptor 1.
Nature
; 499(7459): 438-43, 2013 Jul 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-23863939
3.
Crystal structure of adenosine A2A receptor in complex with clinical candidate Etrumadenant reveals unprecedented antagonist interaction.
Commun Chem
; 6(1): 106, 2023 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37264098
4.
Cryo-EM structures of a LptDE transporter in complex with Pro-macrobodies offer insight into lipopolysaccharide translocation.
Nat Commun
; 13(1): 1826, 2022 04 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35383177
5.
Crystal Structure and Subsequent Ligand Design of a Nonriboside Partial Agonist Bound to the Adenosine A2A Receptor.
J Med Chem
; 64(7): 3827-3842, 2021 04 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-33764785
6.
HCV NS5B polymerase inhibitors 2: Synthesis and in vitro activity of (1,1-dioxo-2H-[1,2,4]benzothiadiazin-3-yl) azolo[1,5-a]pyridine and azolo[1,5-a]pyrimidine derivatives.
Bioorg Med Chem Lett
; 19(15): 4480-3, 2009 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19500983
7.
Crystal Structure of CC Chemokine Receptor 2A in Complex with an Orthosteric Antagonist Provides Insights for the Design of Selective Antagonists.
Structure
; 27(3): 427-438.e5, 2019 03 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30581043
8.
Towards high throughput GPCR crystallography: In Meso soaking of Adenosine A2A Receptor crystals.
Sci Rep
; 8(1): 41, 2018 01 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29311713
9.
X-ray free electron laser: opportunities for drug discovery.
Essays Biochem
; 61(5): 529-542, 2017 11 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29118098
10.
Decoding Corticotropin-Releasing Factor Receptor Type 1 Crystal Structures.
Curr Mol Pharmacol
; 10(4): 334-344, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-28183242
11.
Structures of Human A1 and A2A Adenosine Receptors with Xanthines Reveal Determinants of Selectivity.
Structure
; 25(8): 1275-1285.e4, 2017 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28712806
12.
Controlling the Dissociation of Ligands from the Adenosine A2A Receptor through Modulation of Salt Bridge Strength.
J Med Chem
; 59(13): 6470-9, 2016 07 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-27312113
13.
Discovery and structure-activity relationship of potent and selective covalent inhibitors of transglutaminase 2 for Huntington's disease.
J Med Chem
; 55(3): 1021-46, 2012 Feb 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-22224594
14.
Fragment-based identification of Hsp90 inhibitors.
ChemMedChem
; 4(6): 963-6, 2009 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-19301319