Detalhe da pesquisa
1.
Investigation of the activity of a novel tropolone in osteosarcoma.
Drug Dev Res
; 85(1): e22129, 2024 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-37961833
2.
Two distinct amphipathic peptide antibiotics with systemic efficacy.
Proc Natl Acad Sci U S A
; 117(32): 19446-19454, 2020 08 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32723829
3.
LC-MS/MS method for the quantitation of a dual PI3K/BRD4 inhibitor SF2523 in mouse plasma: Application to plasma protein binding and metabolism studies.
Biomed Chromatogr
; 37(8): e5643, 2023 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-37042063
4.
Evaluation of geranylgeranyl diphosphate synthase inhibition as a novel strategy for the treatment of osteosarcoma and Ewing sarcoma.
Drug Dev Res
; 84(1): 62-74, 2023 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36433690
5.
A Simultaneous Extraction/Derivatization Strategy for Quantitation of Vitamin D in Dried Blood Spots Using LC-MS/MS: Application to Biomarker Study in Subjects Tested for SARS-CoV-2.
Int J Mol Sci
; 24(6)2023 Mar 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-36982565
6.
A simple, high-throughput and validated LC-MS/MS method for the determination of azithromycin in human plasma and its application to a clinical pharmacokinetic study.
Biomed Chromatogr
; 36(10): e5443, 2022 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-35789011
7.
A Concise Review of Liquid Chromatography-Mass Spectrometry-Based Quantification Methods for Short Chain Fatty Acids as Endogenous Biomarkers.
Int J Mol Sci
; 23(21)2022 Nov 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36362272
8.
ZIP8-Mediated Intestinal Dysbiosis Impairs Pulmonary Host Defense against Bacterial Pneumonia.
Int J Mol Sci
; 23(3)2022 Jan 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-35162945
9.
Population Pharmacokinetics of Diethylcarbamazine in Patients with Lymphatic Filariasis and Healthy Individuals.
Antimicrob Agents Chemother
; 65(10): e0031721, 2021 09 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-34310218
10.
Pharmacokinetic and safety study of co-administration of albendazole, diethylcarbamazine, Ivermectin and azithromycin for the integrated treatment of Neglected Tropical Diseases.
Clin Infect Dis
; 2020 Aug 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-32818264
11.
A rapid and sensitive bioanalytical LC-MS/MS method for the quantitation of a novel CDK5 inhibitor 20-223 (CP668863) in plasma: Application to in vitro metabolism and plasma protein-binding studies.
Biomed Chromatogr
; 34(8): e4859, 2020 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-32307720
12.
Simultaneous Quantitation of S(+)- and R(-)-Baclofen and Its Metabolite in Human Plasma and Cerebrospinal Fluid using LC-APCI-MS/MS: An Application for Clinical Studies.
Molecules
; 25(2)2020 Jan 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31936209
13.
Assessment of Tissue Distribution and Metabolism of MP1, a Novel Pyrrolomycin, in Mice Using a Validated LC-MS/MS Method.
Molecules
; 25(24)2020 Dec 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-33322110
14.
In Vivo Evaluation of Isoprenoid Triazole Bisphosphonate Inhibitors of Geranylgeranyl Diphosphate Synthase: Impact of Olefin Stereochemistry on Toxicity and Biodistribution.
J Pharmacol Exp Ther
; 371(2): 327-338, 2019 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31420526
15.
Effects of novel pyrrolomycin MP1 in MYCN amplified chemoresistant neuroblastoma cell lines alone and combined with temsirolimus.
BMC Cancer
; 19(1): 837, 2019 Aug 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-31455317
16.
Bioanalytical method development and validation of moxidectin in plasma by LC-MS/MS: Application to in vitro metabolism.
Biomed Chromatogr
; 33(2): e4389, 2019 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-30238696
17.
Preclinical investigation of a potent geranylgeranyl diphosphate synthase inhibitor.
Invest New Drugs
; 36(5): 810-818, 2018 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-29497895
18.
Simultaneous LC-MS/MS analysis of eicosanoids and related metabolites in human serum, sputum and BALF.
Biomed Chromatogr
; 32(3)2018 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-28975688
19.
Simultaneous Quantitation of Isoprenoid Pyrophosphates in Plasma and Cancer Cells Using LC-MS/MS.
Molecules
; 23(12)2018 Dec 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30544938
20.
Simultaneous quantitation of acetylsalicylic acid and clopidogrel along with their metabolites in human plasma using liquid chromatography tandem mass spectrometry.
Biomed Chromatogr
; 30(3): 466-73, 2016 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-26230053