Detalhe da pesquisa
1.
Intrathecal Gene Therapy for Giant Axonal Neuropathy.
N Engl J Med
; 390(12): 1092-1104, 2024 03 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-38507752
2.
High-dose systemic adeno-associated virus vector administration causes liver and sinusoidal endothelial cell injury.
Mol Ther
; 32(4): 952-968, 2024 Apr 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-38327046
3.
Prednisolone and rapamycin reduce the plasma cell gene signature and may improve AAV gene therapy in cynomolgus macaques.
Gene Ther
; 31(3-4): 128-143, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-37833563
4.
Phase I study of liver depot gene therapy in late-onset Pompe disease.
Mol Ther
; 31(7): 1994-2004, 2023 07 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-36805083
5.
Engineering and expression of a RhoA peptide against respiratory syncytial virus infection in plants.
Planta
; 243(2): 451-8, 2016 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-26474991
6.
Stabilization of HAC1 influenza vaccine by spray drying: formulation development and process scale-up.
Pharm Res
; 31(11): 3006-18, 2014 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-24858396
7.
Neonatal Fc Receptor Inhibition Enables Adeno-Associated Virus Gene Therapy Despite Pre-Existing Humoral Immunity.
Hum Gene Ther
; 34(19-20): 1022-1032, 2023 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-36719773
8.
Engineering of a plant-produced virus-like particle to improve the display of the Plasmodium falciparum Pfs25 antigen and transmission-blocking activity of the vaccine candidate.
Vaccine
; 41(4): 938-944, 2023 01 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-36585278
9.
Immune transgene-dependent myocarditis in macaques after systemic administration of adeno-associated virus expressing human acid alpha-glucosidase.
Front Immunol
; 14: 1094279, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37033976
10.
Integrated vector genomes may contribute to long-term expression in primate liver after AAV administration.
Nat Biotechnol
; 2023 Nov 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37932420
11.
Erratum: Intravenous immunoglobulin prevents peripheral liver transduction of intrathecally delivered AAV vectors.
Mol Ther Methods Clin Dev
; 27: 450-451, 2022 Dec 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-36419470
12.
Intravenous immunoglobulin prevents peripheral liver transduction of intrathecally delivered AAV vectors.
Mol Ther Methods Clin Dev
; 27: 272-280, 2022 Dec 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-36320416
13.
Prednisolone reduces the interferon response to AAV in cynomolgus macaques and may increase liver gene expression.
Mol Ther Methods Clin Dev
; 24: 292-305, 2022 Mar 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35211641
14.
Safety and immunogenicity of a plant-derived recombinant protective antigen (rPA)-based vaccine against Bacillus anthracis: A Phase 1 dose-escalation study in healthy adults.
Vaccine
; 40(12): 1864-1871, 2022 03 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35153091
15.
A non-glycosylated, plant-produced human monoclonal antibody against anthrax protective antigen protects mice and non-human primates from B. anthracis spore challenge.
Hum Vaccin
; 7 Suppl: 183-90, 2011.
Artigo
em Inglês
| MEDLINE | ID: mdl-21270531
16.
Plant-based rapid production of recombinant subunit hemagglutinin vaccines targeting H1N1 and H5N1 influenza.
Hum Vaccin
; 7 Suppl: 41-50, 2011.
Artigo
em Inglês
| MEDLINE | ID: mdl-21266846
17.
An influenza N1 neuraminidase-specific monoclonal antibody with broad neuraminidase inhibition activity against H5N1 HPAI viruses.
Hum Vaccin
; 7 Suppl: 199-204, 2011.
Artigo
em Inglês
| MEDLINE | ID: mdl-21922687
18.
Antibodies to plant-produced Plasmodium falciparum sexual stage protein Pfs25 exhibit transmission blocking activity.
Hum Vaccin
; 7 Suppl: 191-8, 2011.
Artigo
em Inglês
| MEDLINE | ID: mdl-21266847
19.
An AAV-based, room-temperature-stable, single-dose COVID-19 vaccine provides durable immunogenicity and protection in non-human primates.
Cell Host Microbe
; 29(9): 1437-1453.e8, 2021 09 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34428428
20.
Immunogenicity of an AAV-based, room-temperature stable, single dose COVID-19 vaccine in mice and non-human primates.
bioRxiv
; 2021 Jan 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-33442684