[Sclerosing pulmonary hemangioma]. / Skleroziruiushchaia gemangioma legkogo.

The paper presents an observation of a 33-year-old female patient with pulmonary hemangioma followed by hemoptysis in hospital and detected by roentgenofluorography. Sclerosing hemangioma is a rarely occurring benign tumor of the lung.

[Relation of the prolongation of life of radically operated lung cancer patients to the state of steroid balance]. / Zavisimost' prodolzhitel'nosti zhizni radikal'no operirovannykh bol'nykh rakom legkogo ot sostoianiia steroidnogo balansa.

An analysis of the rates of steroid hormone excretion and survival time in patients who had undergone radical surgery for lung cancer showed that the said rates may be used as a prognostic variable. Excretion rates of total 17-hydroxycorticosteroids and hydrocortisone proved to be of the highest prognostic value in patients aged 41-50, while in an older age bracket the best results were obtained with androsterone and estrone level measurements.

[Prognostic value of the level of glucocorticoids and androgens in lung cancer patients]. / Prognosticheskoe znachenie urovnia gliukokortikoidnykh i androgennykh gormonov u bol'nykh rakom legkogo.

Under study was the excretion of 17-OCS and 17-KS in 2 male groups operated upon for lung cancer. The first group comprised 25 patients with the postoperative survival for less than a year. The second group-28 patients, whose survival was over 5 years postoperatively. In terms of 17-OCS excretion both groups were found to be identical: the level of 17OCS in them was normal. The excretion of 17-KS in patients of both groups proved to be considerably lower than normal values. However, in patients of the second group the level of 17-KS was higher, compared with the first group, mainly on account of androsterone. Thus, the balance of steroid hormones of glucocorticoid and androgenic series as well as the correlation between them may serve as a criterion of the prognosis for operated lung cancer patients.

[Value of hormone studies for the control of the treatment effectiveness of squamous-cell cancer of the lung]. / Znachenie gormonal'nykh issledovanii dlia kontrolia za éffektivnost'iu lecheniia bol'nykh ploskokletochnym rakom legkogo.

The results of studying the steroid hormones excretion in 90 patients with lung squamous-cell cancer under chemo-radiation therapy are reported. It is shown that an effective treatment is associated with certain changes in the excretion of androsterone, 11 OH 17KS, estradiol, cortisol and pregnanediol.

[Effect of complex treatment on the level of steroid and thyroid hormones in lung cancer]. / Vliianie kompleksnogo lecheniia na uroven' steroidnykh i tireoidnykh gormonov u bol'nykh rakom legkogo

Following the termination of chemoradiation therapy of patients with lung cancer a decreased level of 17-OCS and 17-KS with the urine is observed. A combination of chemoradiation therapy with testosterone-propionate or prednisolone renders a stabilizing effect on the level of corticosteroids excretion. Chemoradiation therapy, used simultabolism. The application of the hormones involved lessens the number of complications during chemoradiation therapy and increases the survival rate in these patients.

[Hormonal balance in women with lung cancer and its changes after combined treatment]. / Gormonal'nyi balans u zhenshchin, bol'nykh rakom legkogo, i ego izmenenie pod vliianiem kombinirovannogo lecheniia.

A relatively more favorable course of lung cancer and higher survival rates observed in female patients than in males make the case for further study of the problem. Endocrine system study group included female lung cancer patients. Blood-ACTH, FSH, LH, STH, T3 and T4 as well as F, 17-CS and estrogen excretion with urine were followed prior to, immediately and long after treatment in 25 menopausal and 11 premenopausal cases (at folliculin phase). Most patients revealed increased levels of free hydrocortisone in blood and urine matched by a lowered excretion of 17-CS. Hyperproduction of ACTH was registered in 40%, whereas 60% showed subnormal concentrations of said hormone. On the average, the levels of estrogens were increased, gonadotropin--decreased, T3--below normal concentrations and T4 and STH--within norm. TTH levels showed a wide-range variation: half that in healthy females-20%, and much higher than in healthy one-65%. Concentration of F was close to normal 15-20 days after surgery while ACTH and 17-CS--after one year. The levels of the other hormones remained virtually unchanged within 1-3 years.

[Morphological criteria of lung cancer regression under the effect of magnetotherapy]. / Morfologischeskie kriterii regressii raka legkogo pod vliianiem magnitoterapii.

The complex investigation (histological, histochemical, morphological, electrone microscopy) of lung cancerous tumors from 20 patients, subjected preoperatively to the action of magnetic fields enhancing the antitumor resistance by developing general nonspecific adaptation reactions: activation and training, has revealed a number of morphological changes which indicate a marked antitumor effect of magnetic fields. These changes were maximum manifest after 20-30 sessions. High-differentiated adenocarcinoma proved to be mostly sensitive to the magnetic field action.

[Impaired synthesis of thyroid hormones in patients with lung cancer]. / Narushenie sinteza tireoidnykh gormonov u bol'nykh rakom legkogo.

Based on cytological assays of the sputum and biochemical analysis of blood in lung cancer patients, it was found that the character of cells of inflammatory series and the intensity of macrophage reaction in association with the altered level of sialic acid, and the presence of C-reactive protein in blood serum may serve for prognostication of the affection course.

[Effectiveness of immunomodulators in multimodal treatment of patients with lung cancer]. / Effektivnost' immunomoduliatorov pri kompleksnom lechenii bol'nykh rakom legkogo.

The analysis of clinical and immunologic findings indicate that retinol and decaris influence functional activity of immune cells at stage II of lung cancer irrespective of histological structure. In stage III, retinol induced changes in proportion of lymphocyte subpopulations, more evident in glandular cancer. Both immunomodulators lowered the number of purulent complications after surgical interventions. It is only retinol that influenced metastatic dissemination in lung cancer stage II-III.

[Pneumonectomy with mediastinal lymphadenectomy in lung cancer]. / Pnevmonéktomiia s mediastinal'noi limfadenéktomiei po povodu raka legkogo.

The authors describe a method for removal of lymph nodes of the anterior and posterior mediastinum during pneumonectomy, which increases considerably the radical character of the operation. The necessity of separate removal of the lung and the mediastinal fat is emphasized. The anterior and posterior mediastinum are opened by a horseshoe-shaped incision. The described operative technique was used in 613 patients. The control group was made up of 240 patients. Three-year and five-year survival in the group of patients studied was 50.2 and 43.6%, respectively, which was higher than in the control group (38.4 and 27.8%, respectively).