Detalhe da pesquisa
1.
Modulation of SETDB1 activity by APQ ameliorates heterochromatin condensation, motor function, and neuropathology in a Huntington's disease mouse model.
J Enzyme Inhib Med Chem
; 36(1): 856-868, 2021 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-33771089
2.
Identification of Optically Active Pyrimidine Derivatives as Selective 5-HT2C Modulators.
Molecules
; 22(9)2017 Aug 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-28846591
3.
Synthesis and biological evaluation of picolinamides and thiazole-2-carboxamides as mGluR5 (metabotropic glutamate receptor 5) antagonists.
Bioorg Med Chem Lett
; 26(1): 140-4, 2016 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26598462
4.
Synthesis and biological evaluation of aryl isoxazole derivatives as metabotropic glutamate receptor 1 antagonists: a potential treatment for neuropathic pain.
Bioorg Med Chem Lett
; 25(6): 1324-8, 2015 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25677662
5.
Facile diverted synthesis of pyrrolidinyl triazoles using organotrifluoroborate: discovery of potential mPTP blockers.
Org Biomol Chem
; 12(47): 9674-82, 2014 Dec 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-25348904
6.
Efficient synthesis of mibefradil analogues: an insight into in vitro stability.
Org Biomol Chem
; 12(30): 5669-81, 2014 Aug 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-24964394
7.
Synthesis and biological evaluation of 2-substituted quinoline 6-carboxamides as potential mGluR1 antagonists for the treatment of neuropathic pain.
Chem Pharm Bull (Tokyo)
; 62(6): 508-18, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-24881656
8.
Crystal structure of (E)-N-[(E)-3-(4-meth-oxy-phen-yl)allyl-idene]naphthalen-1-amine.
Acta Crystallogr Sect E Struct Rep Online
; 70(Pt 11): o1174, 2014 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25484813
9.
Synthesis and biological evaluation of 2-(arylethynyl)quinoline derivatives as mGluR5 antagonists for the treatment of neuropathic pain.
Bioorg Med Chem Lett
; 23(5): 1472-6, 2013 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23333207
10.
(E)-2,2'-[3-(4-Fluoro-phen-yl)prop-2-ene-1,1-di-yl]bis-(3-hy-droxy-5,5-dimethyl-cyclo-hex-2-en-1-one).
Acta Crystallogr Sect E Struct Rep Online
; 69(Pt 3): o397, 2013 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23476580
11.
(E)-N-[(E)-3-(4-Nitro-phen-yl)allyl-idene]naphthalen-1-amine.
Acta Crystallogr Sect E Struct Rep Online
; 69(Pt 4): o548, 2013 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23634087
12.
(E)-2,2'-[3-(4-Chloro-phen-yl)prop-2-ene-1,1-di-yl]bis-(3-hy-droxy-5,5-di-methyl-cyclo-hex-2-en-1-one).
Acta Crystallogr Sect E Struct Rep Online
; 69(Pt 8): o1347, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-24109413
13.
9-[(E)-2-(4-Chloro-phen-yl)ethen-yl]-3,3,6,6-tetra-methyl-2,3,4,5,6,7,8,9-octa-hydro-1H-xanthene-1,8-dione.
Acta Crystallogr Sect E Struct Rep Online
; 69(Pt 10): o1542, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-24098228
14.
(E)-9-(4-Fluoro-styr-yl)-3,3,6,6-tetra-methyl-3,4,5,6,7,9-hexa-hydro-2H-xanthene-1,8-dione.
Acta Crystallogr Sect E Struct Rep Online
; 69(Pt 6): o985, 2013 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23795137
15.
(E)-N-(3,3-Di-phenyl-allyl-idene)-2-(tri-fluoro-meth-yl)aniline.
Acta Crystallogr Sect E Struct Rep Online
; 69(Pt 5): o757, 2013 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23723903
16.
(E)-N-(3,3-Di-phenyl-allyl-idene)naph-thal-en-1-amine.
Acta Crystallogr Sect E Struct Rep Online
; 69(Pt 7): o1025, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-24046605
17.
5-HT2c receptor selectivity and structure-activity relationship of N-methyl-N-(1-methylpiperidin-4-yl)benzenesulfonamide analogs.
Bioorg Med Chem Lett
; 22(1): 347-52, 2012 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22153942
18.
(E)-N-(3,3-Diphenyl-allyl-idene)-3-nitro-aniline.
Acta Crystallogr Sect E Struct Rep Online
; 68(Pt 10): o3030, 2012 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23125797
19.
(E)-N-(3,3-Diphenyl-allyl-idene)-4-nitro-aniline.
Acta Crystallogr Sect E Struct Rep Online
; 68(Pt 10): o3031, 2012 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23125798
20.
(E)-2,2'-[3-(2-Nitro-phen-yl)prop-2-ene-1,1-di-yl]bis-(3-hy-droxy-cyclo-hex-2-en-1-one).
Acta Crystallogr Sect E Struct Rep Online
; 68(Pt 1): o245, 2012 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-22259527