Detalhe da pesquisa
1.
ez-ADiCon: A novel glyco-remodeling based strategy that enables preparation of homogenous antibody-drug conjugates via one-step enzymatic transglycosylation with payload-preloaded bi-antennary glycan complexes.
Bioorg Med Chem Lett
; 80: 129117, 2023 01 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-36584791
2.
RNase H2-initiated ribonucleotide excision repair.
Mol Cell
; 47(6): 980-6, 2012 Sep 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-22864116
3.
Abasic and oxidized ribonucleotides embedded in DNA are processed by human APE1 and not by RNase H2.
Nucleic Acids Res
; 45(19): 11193-11212, 2017 Nov 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-28977421
4.
Crystal structures of RNase H2 in complex with nucleic acid reveal the mechanism of RNA-DNA junction recognition and cleavage.
Mol Cell
; 40(4): 658-70, 2010 Nov 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-21095591
5.
RNase H2 roles in genome integrity revealed by unlinking its activities.
Nucleic Acids Res
; 41(5): 3130-43, 2013 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23355612
6.
The structural and biochemical characterization of human RNase H2 complex reveals the molecular basis for substrate recognition and Aicardi-Goutières syndrome defects.
J Biol Chem
; 286(12): 10540-50, 2011 Mar 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-21177858
7.
Contributions of the two accessory subunits, RNASEH2B and RNASEH2C, to the activity and properties of the human RNase H2 complex.
Nucleic Acids Res
; 37(1): 96-110, 2009 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-19015152
8.
Evolution and thermodynamics of the slow unfolding of hyperstable monomeric proteins.
BMC Evol Biol
; 10: 207, 2010 Jul 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-20615256
9.
Effect of the disease-causing mutations identified in human ribonuclease (RNase) H2 on the activities and stabilities of yeast RNase H2 and archaeal RNase HII.
FEBS J
; 275(19): 4836-49, 2008 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-18721139
10.
Two RNase H2 Mutants with Differential rNMP Processing Activity Reveal a Threshold of Ribonucleotide Tolerance for Embryonic Development.
Cell Rep
; 25(5): 1135-1145.e5, 2018 10 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-30380406
11.
Conformational contagion in a protein: structural properties of a chameleon sequence.
Proteins
; 68(3): 617-25, 2007 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-17510955
12.
Identification of the gene encoding a type 1 RNase H with an N-terminal double-stranded RNA binding domain from a psychrotrophic bacterium.
FEBS J
; 274(14): 3715-3727, 2007 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-17608717
13.
Crystal structure and structure-based mutational analyses of RNase HIII from Bacillus stearothermophilus: a new type 2 RNase H with TBP-like substrate-binding domain at the N terminus.
J Mol Biol
; 356(1): 165-78, 2006 Feb 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-16343535
14.
R-Loop Depletion by Over-expressed RNase H1 in Mouse B Cells Increases Activation-Induced Deaminase Access to the Transcribed Strand without Altering Frequency of Isotype Switching.
J Mol Biol
; 429(21): 3255-3263, 2017 10 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-28065739
15.
Identification of RNase HII from psychrotrophic bacterium, Shewanella sp. SIB1 as a high-activity type RNase H.
FEBS J
; 273(10): 2264-75, 2006 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-16650002
16.
Structure of amyloid beta fragments in aqueous environments.
FEBS J
; 273(1): 150-8, 2006 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-16367755
17.
Crystallization and preliminary crystallographic analysis of type 1 RNase H from the hyperthermophilic archaeon Sulfolobus tokodaii 7.
Acta Crystallogr Sect F Struct Biol Cryst Commun
; 62(Pt 8): 781-4, 2006 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-16880556
18.
Crystallization and preliminary X-ray diffraction study of an active-site mutant of pro-Tk-subtilisin from a hyperthermophilic archaeon.
Acta Crystallogr Sect F Struct Biol Cryst Commun
; 62(Pt 9): 902-5, 2006 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-16946475
19.
RNase H2 catalytic core Aicardi-Goutières syndrome-related mutant invokes cGAS-STING innate immune-sensing pathway in mice.
J Exp Med
; 213(3): 329-36, 2016 Mar 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-26880576
20.
Crystallization and preliminary X-ray diffraction study of thermostable RNase HIII from Bacillus stearothermophilus.
Acta Crystallogr Sect F Struct Biol Cryst Commun
; 61(Pt 3): 293-5, 2005 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-16511022