Detalhe da pesquisa
1.
Force-induced tail-autotomy mitochondrial fission and biogenesis of matrix-excluded mitochondrial-derived vesicles for quality control.
Proc Natl Acad Sci U S A
; 121(14): e2217019121, 2024 Apr 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-38547062
2.
CAG RNAs induce DNA damage and apoptosis by silencing NUDT16 expression in polyglutamine degeneration.
Proc Natl Acad Sci U S A
; 118(19)2021 05 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-33947817
3.
Clinical characteristics of unvaccinated or incompletely vaccinated children with neurological manifestations due to SARS-CoV-2 Omicron infection.
J Med Virol
; 95(7): e28895, 2023 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-37403902
4.
Insulin stimulates atypical protein kinase C-mediated phosphorylation of the neuronal adaptor FE65 to potentiate neurite outgrowth by activating ARF6-Rac1 signaling.
FASEB J
; 36(11): e22594, 2022 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-36250347
5.
Selective loss of 5hmC promotes neurodegeneration in the mouse model of Alzheimer's disease.
FASEB J
; 34(12): 16364-16382, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33058355
6.
ATM and ATR play complementary roles in the behavior of excitatory and inhibitory vesicle populations.
Proc Natl Acad Sci U S A
; 115(2): E292-E301, 2018 01 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-29279380
7.
Genomic integrity and the ageing brain.
Nat Rev Neurosci
; 16(11): 672-84, 2015 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-26462757
8.
CDK5 activator protein p25 preferentially binds and activates GSK3ß.
Proc Natl Acad Sci U S A
; 111(45): E4887-95, 2014 Nov 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-25331900
9.
A critical review of ethanol effects on neuronal firing: A metabolic perspective.
Alcohol Clin Exp Res (Hoboken)
; 48(3): 450-458, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38217065
10.
Chronic alcohol metabolism results in DNA repair infidelity and cell cycle-induced senescence in neurons.
Aging Cell
; 22(2): e13772, 2023 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36691110
11.
A peptide inhibitor that rescues polyglutamine-induced synaptic defects and cell death through suppressing RNA and protein toxicities.
Mol Ther Nucleic Acids
; 29: 102-115, 2022 Sep 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-35795484
12.
Microglial hexokinase 2 deficiency increases ATP generation through lipid metabolism leading to ß-amyloid clearance.
Nat Metab
; 4(10): 1287-1305, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-36203054
13.
Cytosolic delivery of CDK4/6 inhibitor p16 protein using engineered protein crystals for cancer therapy.
Acta Biomater
; 135: 582-592, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34496285
14.
ATM loss disrupts the autophagy-lysosomal pathway.
Autophagy
; 17(8): 1998-2010, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32757690
15.
Low-Density Lipoprotein Receptor-Related Protein 6 Cell Surface Availability Regulates Fuel Metabolism in Astrocytes.
Adv Sci (Weinh)
; 8(16): e2004993, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34180138
16.
Cyclin-Dependent Kinase 5-Dependent BAG3 Degradation Modulates Synaptic Protein Turnover.
Biol Psychiatry
; 87(8): 756-769, 2020 04 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31955914
17.
ATM is activated by ATP depletion and modulates mitochondrial function through NRF1.
J Cell Biol
; 218(3): 909-928, 2019 03 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30642892
18.
Age-related hyperinsulinemia leads to insulin resistance in neurons and cell-cycle-induced senescence.
Nat Neurosci
; 22(11): 1806-1819, 2019 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31636448
19.
Author Correction: Microglial hexokinase 2 deficiency increases ATP generation through lipid metabolism leading to ß-amyloid clearance.
Nat Metab
; 4(10): 1420, 2022 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-36241712
20.
Loopholes in the DNA contract kill neurons.
Nat Neurosci
; 20(9): 1192-1194, 2017 08 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-28849789