Detalhe da pesquisa
1.
Biographical Feature: Marc S. Collett (23 May 1951-11 June 2022): the Battle against Viral Disease Has Lost a Valiant Warrior, and the World Has Lost a Splendid Human Being.
J Virol
; 97(1): e0164322, 2023 01 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-36468860
2.
A phase 2, double-blinded, placebo-controlled trial of toll-like receptor 7/8/9 antagonist, IMO-8400, in dermatomyositis.
J Am Acad Dermatol
; 84(4): 1160-1162, 2021 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-32781178
3.
Negative feedback regulation of NF-κB-inducing kinase is proteasome-dependent but does not require cellular inhibitors of apoptosis.
Biochem Biophys Res Commun
; 450(1): 341-6, 2014 Jul 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-24942881
4.
Smac mimetics activate the E3 ligase activity of cIAP1 protein by promoting RING domain dimerization.
J Biol Chem
; 286(19): 17015-28, 2011 May 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-21393245
5.
Tilsotolimod Exploits the TLR9 Pathway to Promote Antigen Presentation and Type 1 IFN Signaling in Solid Tumors: A Multicenter International Phase I/II Trial (ILLUMINATE-101).
Clin Cancer Res
; 28(23): 5079-5087, 2022 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35917516
6.
Sensitization of human bladder tumor cells to TNF-related apoptosis-inducing ligand (TRAIL)-induced apoptosis with a small molecule IAP antagonist.
Apoptosis
; 16(1): 13-26, 2011 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-20734142
7.
The discovery and structure-activity relationships of pyrano[3,4-b]indole-based inhibitors of hepatitis C virus NS5B polymerase.
Bioorg Med Chem Lett
; 21(11): 3227-31, 2011 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21550237
8.
Tilsotolimod with Ipilimumab Drives Tumor Responses in Anti-PD-1 Refractory Melanoma.
Cancer Discov
; 11(8): 1996-2013, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-33707233
9.
The discovery and structure-activity relationships of pyrano[3,4-b]indole based inhibitors of hepatitis C virus NS5B polymerase.
Bioorg Med Chem Lett
; 20(9): 2968-73, 2010 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20347591
10.
Molecular mechanism of hepatitis C virus replicon variants with reduced susceptibility to a benzofuran inhibitor, HCV-796.
Antimicrob Agents Chemother
; 52(9): 3327-38, 2008 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-18559648
11.
Combination of IAP antagonist and IFNγ activates novel caspase-10- and RIPK1-dependent cell death pathways.
Cell Death Differ
; 24(3): 481-491, 2017 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-28106882
12.
Birinapant (TL32711), a bivalent SMAC mimetic, targets TRAF2-associated cIAPs, abrogates TNF-induced NF-κB activation, and is active in patient-derived xenograft models.
Mol Cancer Ther
; 13(4): 867-79, 2014 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-24563541
13.
Birinapant, a smac-mimetic with improved tolerability for the treatment of solid tumors and hematological malignancies.
J Med Chem
; 57(9): 3666-77, 2014 May 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-24684347
14.
The novel SMAC mimetic birinapant exhibits potent activity against human melanoma cells.
Clin Cancer Res
; 19(7): 1784-94, 2013 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23403634
15.
Smac mimetic enables the anticancer action of BCG-stimulated neutrophils through TNF-α but not through TRAIL and FasL.
J Leukoc Biol
; 92(1): 233-44, 2012 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-22517918
16.
Smac mimetic reverses resistance to TRAIL and chemotherapy in human urothelial cancer cells.
Cancer Biol Ther
; 10(9): 885-92, 2010 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20814238
17.
TWEAK-FN14 signaling induces lysosomal degradation of a cIAP1-TRAF2 complex to sensitize tumor cells to TNFalpha.
J Cell Biol
; 182(1): 171-84, 2008 Jul 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-18606850
18.
IAP antagonists target cIAP1 to induce TNFalpha-dependent apoptosis.
Cell
; 131(4): 682-93, 2007 Nov 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-18022363
19.
Molecular mechanism of a thumb domain hepatitis C virus nonnucleoside RNA-dependent RNA polymerase inhibitor.
Antimicrob Agents Chemother
; 50(12): 4103-13, 2006 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-16940072
20.
Newly synthesized hepatitis C virus replicon RNA is protected from nuclease activity by a protease-sensitive factor(s).
J Virol
; 78(18): 10202-5, 2004 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-15331754