Detalhe da pesquisa
1.
A light-inducible protein clustering system for in vivo analysis of α-synuclein aggregation in Parkinson disease.
PLoS Biol
; 20(3): e3001578, 2022 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35263320
2.
Reducing huntingtin by immunotherapy delays disease progression in a mouse model of Huntington disease.
Neurobiol Dis
; 190: 106376, 2024 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-38092268
3.
Tau: a biomarker of Huntington's disease.
Mol Psychiatry
; 28(10): 4070-4083, 2023 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-37749233
4.
Detection of antibodies against the huntingtin protein in human plasma.
Cell Mol Life Sci
; 80(2): 45, 2023 Jan 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-36651994
5.
Understanding the role of the hematopoietic niche in Huntington's disease's phenotypic expression: in vivo evidence using a parabiosis model.
Neurobiol Dis
; 180: 106091, 2023 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-36967065
6.
Prion-like properties of the mutant huntingtin protein in living organisms: the evidence and the relevance.
Mol Psychiatry
; 27(1): 269-280, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34711942
7.
Passive immunization against phosphorylated tau improves features of Huntington's disease pathology.
Mol Ther
; 30(4): 1500-1522, 2022 04 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35051614
8.
Current and future applications of induced pluripotent stem cell-based models to study pathological proteins in neurodegenerative disorders.
Mol Psychiatry
; 26(7): 2685-2706, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-33495544
9.
Shedding a new light on Huntington's disease: how blood can both propagate and ameliorate disease pathology.
Mol Psychiatry
; 26(9): 5441-5463, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32514103
10.
MS-275 (Entinostat) Promotes Radio-Sensitivity in PAX3-FOXO1 Rhabdomyosarcoma Cells.
Int J Mol Sci
; 22(19)2021 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34639012
11.
Beneficial effects of cysteamine in Thy1-α-Syn mice and induced pluripotent stem cells with a SNCA gene triplication.
Neurobiol Dis
; 145: 105042, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32798729
12.
Use of adeno-associated virus-mediated delivery of mutant huntingtin to study the spreading capacity of the protein in mice and non-human primates.
Neurobiol Dis
; 141: 104951, 2020 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32439599
13.
Evidence for the spread of human-derived mutant huntingtin protein in mice and non-human primates.
Neurobiol Dis
; 141: 104941, 2020 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32422281
14.
Inhibiting cellular uptake of mutant huntingtin using a monoclonal antibody: Implications for the treatment of Huntington's disease.
Neurobiol Dis
; 141: 104943, 2020 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32407769
15.
Microglial physiological properties and interactions with synapses are altered at presymptomatic stages in a mouse model of Huntington's disease pathology.
J Neuroinflammation
; 17(1): 98, 2020 Apr 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-32241286
16.
Are immunotherapies for Huntington's disease a realistic option?
Mol Psychiatry
; 24(3): 364-377, 2019 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29487401
17.
Antibody-based therapies for Huntington's disease: current status and future directions.
Neurobiol Dis
; 132: 104569, 2019 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31398458
18.
Corrigendum to "Reducing huntingtin by immunotherapy delays disease progression in a mouse model of Huntington disease" [Neurobiology of Disease, 2024 Jan:190:106376].
Neurobiol Dis
; 193: 106444, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-38402018
19.
Portrait of blood-derived extracellular vesicles in patients with Parkinson's disease.
Neurobiol Dis
; 124: 163-175, 2019 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30408591
20.
Outcome of cell suspension allografts in a patient with Huntington's disease.
Ann Neurol
; 84(6): 950-956, 2018 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30286516