Detalhe da pesquisa
1.
International Union of Basic and Clinical Pharmacology. CIX. Differences and Similarities between Human and Rodent Prostaglandin E2 Receptors (EP1-4) and Prostacyclin Receptor (IP): Specific Roles in Pathophysiologic Conditions.
Pharmacol Rev
; 72(4): 910-968, 2020 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32962984
2.
Interaction between PGI2 and ET-1 pathways in vascular smooth muscle from Group-III pulmonary hypertension patients.
Prostaglandins Other Lipid Mediat
; 146: 106388, 2020 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31672620
3.
Prostanoid EP2 Receptors Are Up-Regulated in Human Pulmonary Arterial Hypertension: A Key Anti-Proliferative Target for Treprostinil in Smooth Muscle Cells.
Int J Mol Sci
; 19(8)2018 Aug 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30103548
4.
Inotropic Effects of Prostacyclins on the Right Ventricle Are Abolished in Isolated Rat Hearts With Right-Ventricular Hypertrophy and Failure.
J Cardiovasc Pharmacol
; 69(1): 1-12, 2017 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-27652910
5.
Inhibition of phosphodiesterase 2 augments cGMP and cAMP signaling to ameliorate pulmonary hypertension.
Circulation
; 130(6): 496-507, 2014 Aug 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-24899690
6.
The mechanistic basis of prostacyclin and its stable analogues in pulmonary arterial hypertension: Role of membrane versus nuclear receptors.
Prostaglandins Other Lipid Mediat
; 120: 56-71, 2015 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-25917921
7.
Ex vivo relaxations of pulmonary arteries induced by prostacyclin mimetics are highly dependent of the precontractile agents.
Prostaglandins Other Lipid Mediat
; 121(Pt A): 46-52, 2015 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-26362969
8.
Attenuated vascular responsiveness to K+ channel openers in diabetes mellitus: the differential role of reactive oxygen species.
Gen Physiol Biophys
; 32(4): 527-34, 2013 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-23940092
9.
Relative Recovery of Non-Alcoholic Fatty Liver Disease (NAFLD) in Diet-Induced Obese Rats.
Nutrients
; 16(1)2023 Dec 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-38201945
10.
Prostacyclin mimetics inhibit DRP1-mediated pro-proliferative mitochondrial fragmentation in pulmonary arterial hypertension.
Vascul Pharmacol
; 151: 107194, 2023 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37442283
11.
The Concise Guide to PHARMACOLOGY 2023/24: G protein-coupled receptors.
Br J Pharmacol
; 180 Suppl 2: S23-S144, 2023 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-38123151
12.
Inhibition of vascular adenosine triphosphate-sensitive potassium channels by sympathetic tone during sepsis.
Crit Care Med
; 40(4): 1261-8, 2012 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-22425821
13.
Therapeutic potential of inhibiting histone 3 lysine 27 demethylases: a review of the literature.
Clin Epigenetics
; 14(1): 98, 2022 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35915507
14.
Smooth muscle proliferation and role of the prostacyclin (IP) receptor in idiopathic pulmonary arterial hypertension.
Am J Respir Crit Care Med
; 182(9): 1161-70, 2010 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20622039
15.
The Prostacyclin Analogue, Treprostinil, Used in the Treatment of Pulmonary Arterial Hypertension, is a Potent Antagonist of TREK-1 and TREK-2 Potassium Channels.
Front Pharmacol
; 12: 705421, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34267666
16.
THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: G protein-coupled receptors.
Br J Pharmacol
; 178 Suppl 1: S27-S156, 2021 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-34529832
17.
The large-conductance Ca2+-activated K+ channel is essential for innate immunity.
Nature
; 427(6977): 853-8, 2004 Feb 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-14985765
18.
Bronchodilation induced by PGE2 is impaired in Group III pulmonary hypertension.
Br J Pharmacol
; 177(1): 161-174, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31476020
19.
Selexipag in the management of pulmonary arterial hypertension: an update.
Drug Healthc Patient Saf
; 11: 55-64, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31496830
20.
Adverse Events of Prostacyclin Mimetics in Pulmonary Arterial Hypertension: A Systematic Review and Meta-Analysis.
J Clin Med
; 8(4)2019 04 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-30970653