Detalhe da pesquisa
1.
hRpn13 shapes the proteome and transcriptome through epigenetic factors HDAC8, PADI4, and transcription factor NF-κB p50.
Mol Cell
; 84(3): 522-537.e8, 2024 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38151017
2.
Saturation genome editing of 11 codons and exon 13 of BRCA2 coupled with chemotherapeutic drug response accurately determines pathogenicity of variants.
PLoS Genet
; 19(9): e1010940, 2023 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37713444
3.
A structurally conserved site in AUP1 binds the E2 enzyme UBE2G2 and is essential for ER-associated degradation.
PLoS Biol
; 19(12): e3001474, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34879065
4.
dbGuide: a database of functionally validated guide RNAs for genome editing in human and mouse cells.
Nucleic Acids Res
; 49(D1): D871-D876, 2021 01 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-33051688
5.
A structure-based designed small molecule depletes hRpn13Pru and a select group of KEN box proteins.
Nat Commun
; 15(1): 2485, 2024 Mar 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-38509117