Detalhe da pesquisa
1.
Benzoxazolinone aryl sulfonamides as potent, selective Nav1.7 inhibitors with in vivo efficacy in a preclinical pain model.
Bioorg Med Chem Lett
; 27(12): 2683-2688, 2017 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28465103
2.
2-Aminopyridines as Potent and Selective Nav1.8 Inhibitors Exhibiting Efficacy in a Nonhuman Primate Pain Model.
ACS Med Chem Lett
; 15(6): 917-923, 2024 Jun 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-38894930
3.
Association of respiratory failure with inhibition of NaV1.6 in the phrenic nerve.
Channels (Austin)
; 16(1): 230-243, 2022 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-36239534
4.
Nav1.7 target modulation and efficacy can be measured in nonhuman primate assays.
Sci Transl Med
; 13(594)2021 05 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-34011626
5.
Identification, localization and receptor characterization of novel mammalian substance P-like peptides.
Gene
; 296(1-2): 205-12, 2002 Aug 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-12383518
6.
A novel selective positive allosteric modulator of metabotropic glutamate receptor subtype 5 has in vivo activity and antipsychotic-like effects in rat behavioral models.
J Pharmacol Exp Ther
; 313(1): 199-206, 2005 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-15608073
7.
Allosteric modulation of group III metabotropic glutamate receptor 4: a potential approach to Parkinson's disease treatment.
Proc Natl Acad Sci U S A
; 100(23): 13668-73, 2003 Nov 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-14593202