Detalhe da pesquisa
1.
Neurexin 2 p.G849D variant, implicated in Parkinson's disease, increases reactive oxygen species, and reduces cell viability and mitochondrial membrane potential in SH-SY5Y cells.
J Neural Transm (Vienna)
; 129(12): 1435-1446, 2022 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-36242655
2.
Interaction analysis of statistically enriched mutations identified in Cameroon recombinant subtype CRF02_AG that can influence the development of Dolutegravir drug resistance mutations.
BMC Infect Dis
; 21(1): 379, 2021 Apr 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-33892628
3.
Designing a course model for distance-based online bioinformatics training in Africa: The H3ABioNet experience.
PLoS Comput Biol
; 13(10): e1005715, 2017 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-28981516
4.
Resistance related metabolic pathways for drug target identification in Mycobacterium tuberculosis.
BMC Bioinformatics
; 17: 75, 2016 Feb 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-26856535
5.
Molecular Modeling of Subtype-Specific Tat Protein Signatures to Predict Tat-TAR Interactions That May Be Involved in HIV-Associated Neurocognitive Disorders.
Front Microbiol
; 13: 866611, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35464972
6.
The determination of the effect(s) of solute carrier family 22-member 2 (SLC22A2) haplotype variants on drug binding via molecular dynamic simulation systems.
Sci Rep
; 12(1): 16936, 2022 10 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-36209293
7.
The Flexible, Extended Coil of the PDZ-Binding Motif of the Three Deadly Human Coronavirus E Proteins Plays a Role in Pathogenicity.
Viruses
; 14(8)2022 08 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36016329
8.
Proteomics analysis of the p.G849D variant in neurexin 2 alpha may reveal insight into Parkinson's disease pathobiology.
Front Aging Neurosci
; 14: 1002777, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36533174
9.
Emerging evidence implicating a role for neurexins in neurodegenerative and neuropsychiatric disorders.
Open Biol
; 11(10): 210091, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34610269
10.
In silico repurposing of a Novobiocin derivative for activity against latency associated Mycobacterium tuberculosis drug target nicotinate-nucleotide adenylyl transferase (Rv2421c).
PLoS One
; 16(11): e0259348, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34727137
11.
Short Communication: HIV-1 Drug Resistance Mutation Analyses of Cameroon-Derived Integrase Sequences.
AIDS Res Hum Retroviruses
; 37(1): 54-56, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32640829
12.
Prioritization of candidate genes for a South African family with Parkinson's disease using in-silico tools.
PLoS One
; 16(3): e0249324, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33770142
13.
Aptamer-Based Diagnostic Systems for the Rapid Screening of TB at the Point-of-Care.
Diagnostics (Basel)
; 11(8)2021 Jul 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-34441287
14.
Molecular dynamic simulations to investigate the structural impact of known drug resistance mutations on HIV-1C Integrase-Dolutegravir binding.
PLoS One
; 15(5): e0223464, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32379830
15.
Correction: Molecular dynamic simulations to investigate the structural impact of known drug resistance mutations on HIV-1C Integrase-Dolutegravir binding.
PLoS One
; 15(6): e0234581, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32502198
16.
Structural Comparison of Diverse HIV-1 Subtypes using Molecular Modelling and Docking Analyses of Integrase Inhibitors.
Viruses
; 12(9)2020 08 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-32858802
17.
Drug Resistance Mutations Against Protease, Reverse Transcriptase and Integrase Inhibitors in People Living With HIV-1 Receiving Boosted Protease Inhibitors in South Africa.
Front Microbiol
; 11: 438, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32265875
18.
HIV-1 Integrase Diversity and Resistance-Associated Mutations and Polymorphisms Among Integrase Strand Transfer Inhibitor-Naive HIV-1 Patients from Cameroon.
AIDS Res Hum Retroviruses
; 36(5): 450-455, 2020 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-31830799
19.
Genome Sequencing of a Severe Acute Respiratory Syndrome Coronavirus 2 Isolate Obtained from a South African Patient with Coronavirus Disease 2019.
Microbiol Resour Announc
; 9(27)2020 Jul 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-32616644
20.
Structure based identification of novel inhibitors against ATP synthase of Mycobacterium tuberculosis: A combined in silico and in vitro study.
Int J Biol Macromol
; 135: 582-590, 2019 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31121229